Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Carolina E. Pardo"'
Autor:
Kevin D. Brown, Erin M. Siegel, Coy D. Heldermon, Michael P. Kladde, W. Stratford May, Shigetsugu Hatakeyama, Carolina E. Pardo, Ming Tang, Merve Alpay, Wan-Ju Kim, Lingbao Ai
Table S1: Oligonucleotide primer sequences. Table S2: Data obtained from the Cox model. Figure S1: Detailed structure of the human TRIM29 gene locus. Figure S2: Additional TRIM29 gene methylation and transcript abundance analysis. Figure S3: Analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::090308728f31f8018f3e3af1dcaee91f
https://doi.org/10.1158/0008-5472.22403669.v1
https://doi.org/10.1158/0008-5472.22403669.v1
Autor:
Eliza Morton, Hadley Browder, Kevin Kapadia, Carolina E. Pardo, Parker Knight, Alberto Riva, Marie-Pierre L. Gauthier, Michael P. Kladde, Russell P. Darst, Rhonda Bacher
Publikováno v:
Bioinformatics
Summary Differential DNA methylation and chromatin accessibility are associated with disease development, particularly cancer. Methods that allow profiling of these epigenetic mechanisms in the same reaction and at the single-molecule or single-cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89d28c7b1e5e9450883447e40eb3da50
https://pubmed.ncbi.nlm.nih.gov/34125875
https://pubmed.ncbi.nlm.nih.gov/34125875
Autor:
Tomoki Sunose, Michael P. Kladde, Kazuhiko Igarashi, Suming Huang, Jared R. Stees, Yasushi Kudo, Carolina E. Pardo, Mir A. Hossain, Nancy H. Nabilsi, Jörg Bungert, Russell P. Darst, Rosha Poudyal
Publikováno v:
Molecular and Cellular Biology. 36:238-250
Enhancers and promoters assemble protein complexes that ultimately regulate the recruitment and activity of RNA polymerases. Previous work has shown that at least some enhancers form stable protein complexes, leading to the formation of enhanceosomes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3bcdb388f320eb4da0da4fdfbb76b8e
https://doi.org/10.1128/mcb.00723-15
https://doi.org/10.1128/mcb.00723-15
Autor:
Albert G. Tsai, Chih-Lin Hsieh, Michael P. Kladde, Michael R. Lieber, Markus Müschen, Zhengfei Lu, Carolina E. Pardo
Publikováno v:
Molecular and Cellular Biology. 35:1209-1222
Chromosomal translocations are a hallmark of hematopoietic malignancies. CG motifs within translocation fragile zones (typically 20 to 600 bp in size) are prone to chromosomal translocation in lymphomas. Here we demonstrate that the CG motifs in huma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1500dbf99b8d7c33ac4524616ca1c6c5
https://doi.org/10.1128/mcb.01085-14
https://doi.org/10.1128/mcb.01085-14
Autor:
Naohiro Terada, Takashi Hamazaki, Carolina E. Pardo, Katherine E. Santostefano, Michael P. Kladde
Publikováno v:
Journal of Biological Chemistry. 287:30507-30517
Nanog or Gata6-positive cells co-exist and are convertible within the inner cell mass of murine blastocysts and embryonic stem (ES) cells. Previous studies demonstrate fibroblast growth factor receptor 2 (FGFR2) triggers Nanog gene down-regulation an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5abb0bfe37f0066f71bc3e6840680af8
https://doi.org/10.1074/jbc.m112.388181
https://doi.org/10.1074/jbc.m112.388181
Autor:
Amber L. Delmas, Russell P. Darst, Erin M. Siegel, Eugene Izumchenko, Bridget Riggs, Lisa Dyer, Michael P. Kladde, Carolina E. Pardo, Mänette Monroe, Ardeshir Hakam, Kevin D. Brown
Publikováno v:
Carcinogenesis. 32:1625-1633
Aberrant activation of the Wnt/β-catenin signaling axis is a prominent oncogenic mechanism in numerous cancers including cervical cancer. Wnt inhibitory factor-1 (WIF1) is a secreted protein that binds Wnt and antagonizes Wnt activity. While the WIF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a0b3777595eab8dfd3e3eaebdd9bae8
https://doi.org/10.1093/carcin/bgr193
https://doi.org/10.1093/carcin/bgr193
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1288
Chromatin limits the accessibility of DNA to trans-acting factors in transcription, replication, and repair. Although transcriptional variation between cells in a population may contribute to survival and disease, most assays of chromatin structure r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::924f60a1e57bdac7daf0bb06a3325354
https://pubmed.ncbi.nlm.nih.gov/25827879
https://pubmed.ncbi.nlm.nih.gov/25827879
Publikováno v:
Methods in Molecular Biology ISBN: 9781493924738
Chromatin limits the accessibility of DNA to trans-acting factors in transcription, replication, and repair. Although transcriptional variation between cells in a population may contribute to survival and disease, most assays of chromatin structure r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc4ff7b695449abab6ec190e965fc1aa
https://doi.org/10.1007/978-1-4939-2474-5_9
https://doi.org/10.1007/978-1-4939-2474-5_9
Autor:
Coy D. Heldermon, Merve Alpay, Michael P. Kladde, Ming Tang, Carolina E. Pardo, Erin M. Siegel, W. Stratford May, Shigetsugu Hatakeyama, Lingbao Ai, Wan Ju Kim, Kevin D. Brown
TRIM29 (ATDC) exhibits a contextual function in cancer, but seems to exert a tumor-suppressor role in breast cancer. Here, we show that TRIM29 is often silenced in primary breast tumors and cultured tumor cells as a result of aberrant gene hypermethy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4299bcc9510b9e0da634285b0a62f238
https://aperta.ulakbim.gov.tr/record/63399
https://aperta.ulakbim.gov.tr/record/63399
Publikováno v:
Nucleic Acids Research
Spontaneous lytic reactivation of Kaposi's sarcoma-associated herpesvirus (KSHV) occurs at a low rate in latently infected cells in disease and culture. This suggests imperfect epigenetic maintenance of viral transcription programs, perhaps due to va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8e9381b64b7f20541194b9013a228cf
https://pubmed.ncbi.nlm.nih.gov/23361465
https://pubmed.ncbi.nlm.nih.gov/23361465