Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Carolina Bizama"'
Autor:
Javiera Obreque, Luis Vergara-Gómez, Nicolás Venegas, Helga Weber, Gareth I. Owen, Pablo Pérez-Moreno, Pamela Leal, Juan Carlos Roa, Carolina Bizama
Publikováno v:
Biological Research, Vol 56, Iss 1, Pp 1-27 (2023)
Abstract In December 2022 the US Food and Drug Administration (FDA) removed the requirement that drugs in development must undergo animal testing before clinical evaluation, a declaration that now demands the establishment and verification of ex vivo
Externí odkaz:
https://doaj.org/article/53e2cfa4a35d4a9fae6d1f662c519da0
Autor:
Lorena Rosa, Lorena Lobos‐González, Natalia Muñoz‐Durango, Patricia García, Carolina Bizama, Natalia Gómez, Ximena González, Ignacio A. Wichmann, Nicolás Saavedra, Francisca Guevara, Jaime Villegas, Marco Arrese, Catterina Ferreccio, Alexis M. Kalergis, Juan Francisco Miquel, Jaime A. Espinoza, Juan C. Roa
Publikováno v:
Molecular Oncology, Vol 14, Iss 11, Pp 2834-2852 (2020)
Gallbladder stones (cholecystolithiasis) are the main risk factor for gallbladder cancer (GBC), a lethal biliary malignancy with poor survival rates worldwide. Gallbladder stones are thought to damage the gallbladder epithelium and trigger chronic in
Externí odkaz:
https://doaj.org/article/555482fa74f1498e9ea86a122d8b51ed
Integrated genomic analysis reveals mutated ELF3 as a potential gallbladder cancer vaccine candidate
Autor:
Akhilesh Pandey, Eric W. Stawiski, Steffen Durinck, Harsha Gowda, Leonard D. Goldstein, Mustafa A. Barbhuiya, Markus S. Schröder, Sreelakshmi K. Sreenivasamurthy, Sun-Whe Kim, Sameer Phalke, Kushal Suryamohan, Kayla Lee, Papia Chakraborty, Vasumathi Kode, Xiaoshan Shi, Aditi Chatterjee, Keshava Datta, Aafaque A. Khan, Tejaswini Subbannayya, Jing Wang, Subhra Chaudhuri, Sanjiv Gupta, Braj Raj Shrivastav, Bijay S. Jaiswal, Satish S. Poojary, Shushruta Bhunia, Patricia Garcia, Carolina Bizama, Lorena Rosa, Wooil Kwon, Hongbeom Kim, Youngmin Han, Thakur Deen Yadav, Vedam L. Ramprasad, Amitabha Chaudhuri, Zora Modrusan, Juan Carlos Roa, Pramod Kumar Tiwari, Jin-Young Jang, Somasekar Seshagiri
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Gallbladder cancer incidence shows characteristic geographic patterns. Here the authors perform a genomic analysis of gallbladder cancers in patients from countries with high incidence (South Korea, India and Chile) and identify ELF3 and other signif
Externí odkaz:
https://doaj.org/article/4947118a87984a6abb9c9a6e884df1b9
Autor:
Patricia García, Carolina Bizama, Lorena Rosa, Jaime A. Espinoza, Helga Weber, Javier Cerda-Infante, Marianela Sánchez, Viviana P. Montecinos, Justo Lorenzo-Bermejo, Felix Boekstegers, Marcela Dávila-López, Francisca Alfaro, Claudia Leiva-Acevedo, Zasha Parra, Diego Romero, Sumie Kato, Pamela Leal, Marcela Lagos, Juan Carlos Roa
Publikováno v:
Biological Research, Vol 53, Iss 1, Pp 1-17 (2020)
Abstract Background Gallbladder cancer (GBC) is the most common tumor of the biliary tract. The incidence of GBC shows a large geographic variability, being particularly frequent in Native American populations. In Chile, GBC represents the second cau
Externí odkaz:
https://doaj.org/article/a26547339f234670bf41ee3ee9f7bab1
Autor:
Alejandra Sandoval-Bórquez, Iva Polakovicova, Nicolás Carrasco-Véliz, Lorena Lobos-González, Ismael Riquelme, Gonzalo Carrasco-Avino, Carolina Bizama, Enrique Norero, Gareth I. Owen, Juan C. Roa, Alejandro H. Corvalán
Publikováno v:
Clinical Epigenetics, Vol 9, Iss 1, Pp 1-16 (2017)
Abstract Background Multiple aberrant microRNA expression has been reported in gastric cancer. Among them, microRNA-335-5p (miR-335), a microRNA regulated by DNA methylation, has been reported to possess both tumor suppressor and tumor promoter activ
Externí odkaz:
https://doaj.org/article/534111e89d934e5696e16e1b2738b996
Autor:
Luis Vergara-Gómez, Carolina Bizama, Jun Zhong, Kurt Buchegger, Felipe Suárez, Lorena Rosa, Carmen Ili, Helga Weber, Javiera Obreque, Karena Espinoza, Gabriela Repetto, Juan C. Roa, Pamela Leal, Patricia García
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 8; Pages: 7238
Treatment options for advanced gallbladder cancer (GBC) are scarce and usually rely on cytotoxic chemotherapy, but the effectiveness of any regimen is limited and recurrence rates are high. Here, we investigated the molecular mechanisms of acquired r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8693d844ec1a3cd474c64810ab7d3fdb
https://doi.org/10.3390/ijms24087238
https://doi.org/10.3390/ijms24087238
Autor:
José Ignacio Erices, Carolina Bizama, Ignacio Niechi, Daniel Uribe, Arnaldo Rosales, Karen Fabres, Giovanna Navarro-Martínez, Ángelo Torres, Rody San Martín, Juan Carlos Roa, Claudia Quezada-Monrás
Publikováno v:
International Journal of Molecular Sciences. 24:7047
Glioblastoma (GBM) is the most common and malignant primary brain cancer in adults. Without treatment the mean patient survival is approximately 6 months, which can be extended to 15 months with the use of multimodal therapies. The low effectiveness
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bbe4bac58dd6876c1d2b7547e2fbb220
https://doi.org/10.3390/ijms24087047
https://doi.org/10.3390/ijms24087047
Autor:
Carolina Ibañez, De Toro G, Katherine Marcelain, Olga Barajas, Alicia Colombo, Jessica Toro, Feliu E, Miranda N, Lorenzo Bermejo J, Spencer L, Iván Gallegos, Gutierrez L, María Loreto Bravo, Patricia García, Ricardo A. Verdugo, Ricardo Armisen, Villaman C, Sanhueza, Erik Morales, Bustamante E, Maureira I, Carolina Bizama, Salvo M, Carrasco Am, Monica Ahumada
The genomic characterization of solid tumors and a rapidly growing repertoire of target drugs are revolutionizing cancer treatment. Next-generation sequencing (NGS) panels are progressively used in clinical practice for target therapy in high-income
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74b888b52de1214274ee06470952161c
https://doi.org/10.1101/2021.03.19.21253988
https://doi.org/10.1101/2021.03.19.21253988
Autor:
Carolina Bizama, Ismael Riquelme, Enrique Norero, Lorena Lobos-González, Alejandra Sandoval-Bórquez, Nicolás Carrasco-Véliz, Alejandro H. Corvalan, Iva Polakovicova, Gonzalo Carrasco-Avino, Juan Carlos Roa, Gareth I. Owen
Publikováno v:
Clinical Epigenetics. 13
An amendment to this paper has been published and can be accessed via the original article.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f436501d08972a67207c6996a50168b
https://doi.org/10.1186/s13148-021-01036-2
https://doi.org/10.1186/s13148-021-01036-2
Autor:
Marcela Lagos, Juan Carlos Roa, Claudia Leiva-Acevedo, Sumie Kato, Lorena Rosa, Marcela Dávila-López, Helga Weber, Marianela Sanchez, Diego Romero, Javier Cerda-Infante, Jaime A. Espinoza, Justo Lorenzo-Bermejo, Francisca Alfaro, Felix Boekstegers, Carolina Bizama, Patricia García, Zasha Parra, Pamela Leal, Viviana P. Montecinos
Publikováno v:
Biological Research, Volume: 53, Article number: 13, Published: 24 APR 2020
Biological Research, Vol 53, Iss 1, Pp 1-17 (2020)
Biological Research
Biological Research v.53 2020
SciELO Chile
CONICYT Chile
instacron:CONICYT
Biological Research, Vol 53, Iss 1, Pp 1-17 (2020)
Biological Research
Biological Research v.53 2020
SciELO Chile
CONICYT Chile
instacron:CONICYT
Background Gallbladder cancer (GBC) is the most common tumor of the biliary tract. The incidence of GBC shows a large geographic variability, being particularly frequent in Native American populations. In Chile, GBC represents the second cause of can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a43b599c946e435c814a8e6aff06f2b3
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602020000100211&lng=en&tlng=en
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602020000100211&lng=en&tlng=en