Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Carolina B López"'
Publikováno v:
PLoS Biology, Vol 21, Iss 11, p e3002381 (2023)
Antiviral responses are often accompanied by translation inhibition and formation of stress granules (SGs) in infected cells. However, the triggers for these processes and their role during infection remain subjects of active investigation. Copy-back
Externí odkaz:
https://doaj.org/article/ad2bec942e104146b2af82efe650e303
Autor:
Bradley E Hiller, Yongjun Yin, Yi-Chieh Perng, Ítalo de Araujo Castro, Lindsey E Fox, Marissa C Locke, Kristen J Monte, Carolina B López, David M Ornitz, Deborah J Lenschow
Publikováno v:
PLoS Pathogens, Vol 18, Iss 6, p e1010228 (2022)
Influenza A virus (IAV) preferentially infects conducting airway and alveolar epithelial cells in the lung. The outcome of these infections is impacted by the host response, including the production of various cytokines, chemokines, and growth factor
Externí odkaz:
https://doaj.org/article/a0c0e8f27fd44ecfa41112866636508b
Autor:
Yan Sun, Eun Ji Kim, Sébastien A Felt, Louis J Taylor, Divyansh Agarwal, Gregory R Grant, Carolina B López
Publikováno v:
PLoS Pathogens, Vol 15, Iss 10, p e1008099 (2019)
[This corrects the article DOI: 10.1371/journal.ppat.1007707.].
Externí odkaz:
https://doaj.org/article/0891016d0791448aaf52f6852bba3f87
Autor:
Yan Sun, Eun Ji Kim, Sébastien A Felt, Louis J Taylor, Divyansh Agarwal, Gregory R Grant, Carolina B López
Publikováno v:
PLoS Pathogens, Vol 15, Iss 4, p e1007707 (2019)
Defective viral genomes of the copy-back type (cbDVGs) are the primary initiators of the antiviral immune response during infection with respiratory syncytial virus (RSV) both in vitro and in vivo. However, the mechanism governing cbDVG generation re
Externí odkaz:
https://doaj.org/article/c9ed71e811864fa081c42fb6cc344dd6
Autor:
Carolina B López
Publikováno v:
PLoS Pathogens, Vol 15, Iss 1, p e1007450 (2019)
Externí odkaz:
https://doaj.org/article/4582f865a44f488fa891fc7c6a40a6d5
Autor:
Gaia Muallem, Sagie Wagage, Yan Sun, Jonathan H DeLong, Alex Valenzuela, David A Christian, Gretchen Harms Pritchard, Qun Fang, Elizabeth L Buza, Deepika Jain, M Merle Elloso, Carolina B López, Christopher A Hunter
Publikováno v:
PLoS Pathogens, Vol 13, Iss 1, p e1006173 (2017)
Respiratory paramyxoviruses are important causes of morbidity and mortality, particularly of infants and the elderly. In humans, a T helper (Th)2-biased immune response to these infections is associated with increased disease severity; however, littl
Externí odkaz:
https://doaj.org/article/fede9b5bf3fe4e05802f0a6a11661c92
Autor:
Naomi H Philip, Alexandra DeLaney, Lance W Peterson, Melanie Santos-Marrero, Jennifer T Grier, Yan Sun, Meghan A Wynosky-Dolfi, Erin E Zwack, Baofeng Hu, Tayla M Olsen, Anthony Rongvaux, Scott D Pope, Carolina B López, Andrew Oberst, Daniel P Beiting, Jorge Henao-Mejia, Igor E Brodsky
Publikováno v:
PLoS Pathogens, Vol 12, Iss 10, p e1005910 (2016)
Caspases regulate cell death programs in response to environmental stresses, including infection and inflammation, and are therefore critical for the proper operation of the mammalian immune system. Caspase-8 is necessary for optimal production of in
Externí odkaz:
https://doaj.org/article/f64d18916f2d4f71922dc3bc9241243c
Autor:
Yan Sun, Deepika Jain, Cynthia J Koziol-White, Emmanuelle Genoyer, Micah Gilbert, Karla Tapia, Reynold A Panettieri, Richard L Hodinka, Carolina B López
Publikováno v:
PLoS Pathogens, Vol 11, Iss 9, p e1005122 (2015)
Human respiratory syncytial virus (RSV) is a major cause of severe respiratory illness in children and susceptible adults. RSV blocks the development of the innate antiviral immune response and can grow to high titers in the respiratory tract. Here w
Externí odkaz:
https://doaj.org/article/742a0d7e96084e969b7c107ddd4c7989
Autor:
Karla Tapia, Won-Keun Kim, Yan Sun, Xiomara Mercado-López, Emily Dunay, Megan Wise, Michael Adu, Carolina B López
Publikováno v:
PLoS Pathogens, Vol 9, Iss 10, p e1003703 (2013)
The innate immune response to viruses is initiated when specialized cellular sensors recognize viral danger signals. Here we show that truncated forms of viral genomes that accumulate in infected cells potently trigger the sustained activation of the
Externí odkaz:
https://doaj.org/article/e829f6399df14ecfa75532b2aa639874
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37334 (2012)
A burst in the production of pro-inflammatory molecules characterizes the beginning of the host response to infection. Cytokines, chemokines, and growth factors work in concert to control pathogen replication and activate innate and adaptive immune r
Externí odkaz:
https://doaj.org/article/1d1d3984f3d14f1ea43686ad69c5aa9f