Data from Test Performance of Immunologic Fecal Occult Blood Testing and Sigmoidoscopy Compared with Primary Colonoscopy Screening for Colorectal Advanced Adenomas

Autor: Ad A.M. Masclee, Reinhold W. Stockbrügger, Manon van Engeland, Jan B.M.J. Janssen, Gerrit A. Meijer, Adriaan P. de Bruïne, Silvia Sanduleanu, Daisy M.A.E. Jonkers, Carolina A.J. Khalid-de Bakker

Given the current increase in colorectal cancer screening, information on performance of screening tests is needed, especially in groups with a presumed lower test performance. We compared test performance of immunologic fecal occult blood testing (F

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9f6689b07c49e53db42cea1147985f44
https://doi.org/10.1158/1940-6207.c.6545114.v1

Perspective on This Article from Test Performance of Immunologic Fecal Occult Blood Testing and Sigmoidoscopy Compared with Primary Colonoscopy Screening for Colorectal Advanced Adenomas

Autor: Ad A.M. Masclee, Reinhold W. Stockbrügger, Manon van Engeland, Jan B.M.J. Janssen, Gerrit A. Meijer, Adriaan P. de Bruïne, Silvia Sanduleanu, Daisy M.A.E. Jonkers, Carolina A.J. Khalid-de Bakker

Perspective on This Article from Test Performance of Immunologic Fecal Occult Blood Testing and Sigmoidoscopy Compared with Primary Colonoscopy Screening for Colorectal Advanced Adenomas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a8eca8b8f5521ed89cbe837697012e5
https://doi.org/10.1158/1940-6207.22526489

Data from GATA4 and GATA5 are Potential Tumor Suppressors and Biomarkers in Colorectal Cancer

Autor: Manon van Engeland, Adriaan P. de Bruïne, James G. Herman, Stephen B. Baylin, Gerrit A. Meijer, Beatriz Carvalho, Wim van Criekinge, Joost Louwagie, Matty P. Weijenberg, Daisy Jonkers, Carolina A.J. Khalid-de Bakker, Silvia Sanduleanu, Yasuhito Yuasa, Yoshimitsu Akiyama, Kim M. Smits, Kathleen L.J. Daenen, Kim A.D. Wouters, Veerle Melotte, Sandra M. van den Bosch, Marjolein H.F.M. Lentjes, Debby M.E.I. Hellebrekers

Purpose: The transcription factors GATA4 and GATA5 are involved in gastrointestinal development and are inactivated by promoter hypermethylation in colorectal cancer. Here, we evaluated GATA4/5 promoter methylation as potential biomarkers for noninva

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https://doi.org/10.1158/1078-0432.c.6517879

Data from Methylation of TFPI2 in Stool DNA: A Potential Novel Biomarker for the Detection of Colorectal Cancer

Autor: Nita Ahuja, Kornel E. Schuebel, Manon Van Engeland, Stephen B. Baylin, James G. Herman, Katja Bierau, Christine Iacobuzio-Donahue, Frank A. Oort, Gerrit A. Meijer, Reinhold W. Stockbrügger, Daisy M.A.E. Jonkers, Carolina A.J. Khalid-de Bakker, Kim M. Smits, Adriaan P. de Bruïne, Wolfram Kleeberger, Timothy A. Chan, Joost Louwagie, Leander Van Neste, Kelly E. McGarvey, Joo Mi Yi, Mashaal Dhir, Sabine C. Glöckner

We have used a gene expression array–based strategy to identify the methylation of tissue factor pathway inhibitor 2 (TFPI2), a potential tumor suppressor gene, as a frequent event in human colorectal cancers (CRC). TFPI2 belongs to the recently de

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https://doi.org/10.1158/0008-5472.c.6498350

DNA Methylation of Phosphatase and Actin Regulator 3 Detects Colorectal Cancer in Stool and Complements FIT

Autor: Chris J. J. Mulder, Maarten Neerincx, Sandra Mongera, Veerle M.H. Coupé, Linda J.W. Bosch, Daisy Jonkers, Wim Van Criekinge, Madeleine Grooteclaes, Frank A. Oort, Jochim S. Terhaar sive Droste, Carolina A.J. Khalid-de Bakker, Manon van Engeland, Beatriz Carvalho, Ad A.M. Masclee, Joost Louwagie, Gerrit A. Meijer, Veerle Melotte

Publikováno v: Cancer Prevention Research, 5(3), 464-472. American Association for Cancer Research Inc.
Cancer prevention research, 5(3), 464-472. American Association for Cancer Research Inc.
Bosch, L J W, Oort, F A, Neerincx, M, Khalid-de Bakker, C A, Terhaar sive Droste, J S, Melotte, V, Jonkers, D M A E, Masclee, A A M, Mongera, S, Grooteclaes, M, Louwagie, J, Van Criekinge, W, Coupé, V M H, Mulder, C J J, van Engeland, M, Carvalho, B & Meijer, G A 2012, ' DNA methylation of phosphatase and actin regulator 3 detects colorectal cancer in stool and complements FIT ', Cancer Prevention Research, vol. 5, no. 3, pp. 464-472 . https://doi.org/10.1158/1940-6207.CAPR-11-0315

Using a bioinformatics-based strategy, we set out to identify hypermethylated genes that could serve as biomarkers for early detection of colorectal cancer (CRC) in stool. In addition, the complementary value to a Fecal Immunochemical Test (FIT) was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41448bf87151c1d2c93d3423c7575d96
https://doi.org/10.1158/1940-6207.capr-11-0315