Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Carolina Añazco"'
Autor:
Christine Kreindl, Sandra A. Soto-Alarcón, Miltha Hidalgo, Ana L. Riveros, Carolina Añazco, Rodrigo Pulgar, Omar Porras
Publikováno v:
Antioxidants, Vol 13, Iss 2, p 159 (2024)
Deficient wound healing is frequently observed in patients diagnosed with diabetes, a clinical complication that compromises mobility and leads to limb amputation, decreasing patient autonomy and family lifestyle. Fibroblasts are crucial for secretin
Externí odkaz:
https://doaj.org/article/4b2ac301fde949998a2793aa9248d842
Autor:
Paulina Araya, Armando Rojas, Ramón Perez, Ileana Gonzalez, Fernando Delgado-López, Jacqueline Romero, Carolina Añazco
Publikováno v:
Inflammation Research. 68:639-642
The hypoxic milieu at tumor microenvironment is able to drive the behavior of infiltrating tumor cells. Considering that hypoxia-mediated HMGB1 release is known to promote tumor growth, as well to enhance the pro-tumoral profile of M2 macrophages by
Autor:
Carolina Añazco, Jacqueline Romero, Armando Rojas, Fernando Delgado-López, Paulina Araya, Ileana Gonzalez, Ramón Pérez-Castro
Publikováno v:
Cancer Microenvironment. 11:97-105
Tumors are complex tissues composed of variable amounts of both non-cellular components (matrix proteins) and a multitude of stromal cell types, which are under an active cross-talk with tumor cells. Tumor-associated macrophages (TAMs) are the major
Publikováno v:
Carcinogenesis. 39:515-521
A growing body of epidemiologic evidence suggests that people with diabetes are at a significantly higher risk of many forms of cancer. However, the molecular mechanisms underlying this association are not fully understood. Cancer cells are surrounde
Autor:
Carolina Añazco, Mohamed Rafi, Alberto José López-Jiménez, Lorenzo Vega-Montoto, Billy G. Hudson, Roberto M. Vanacore, Ming-Zhi Zhang
Publikováno v:
Journal of Biological Chemistry. 291:25999-26012
The 7S dodecamer is recognized as an important structural cross-linking domain of collagen IV networks that provide mechanical stability to basement membranes, a specialized form of extracellular matrix essential for the development and maintenance o
Autor:
Armando Rojas, Paz Robert, Felipe Oyarzun-Ampuero, Ileana Gonzalez, Carolina Añazco, Maite A. Castro
Publikováno v:
Current topics in medicinal chemistry. 18(14)
Collagen, the most abundant component in mammalian tissues, has a crucial impact at skin level. Both promotion and maintenance of cross-linked collagen at the skin are critical to sustain the functionality and appearance of that tissue. Lysyl oxidase
Autor:
Erik Morales, Armando Rojas, Ramón Pérez-Castro, Carolina Añazco, Fernando Delgado-López, Jorge Llanos, Ileana Gonzalez, Paulina Araya, Israel Rojas, Jacqueline Romero
Publikováno v:
Tumor Biology. 37:3321-3329
The monocyte-macrophage lineage shows a high degree of diversity and plasticity. Once they infiltrate tissues, they may acquire two main functional phenotypes, being known as the classically activated type 1 macrophages (M1) and the alternative activ
Autor:
María Isabel Niemeyer, Carolina Añazco, Gaspar Peña-Münzenmayer, Francisco V. Sepúlveda, L. Pablo Cid, Carla Araya
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 465:1715-1726
TASK-2 (K2P5.1) is a background K(+) channel opened by extra- or intracellular alkalinisation that plays a role in renal bicarbonate handling, central chemoreception and cell volume regulation. Here, we present results that suggest that TASK-2 is als
Publikováno v:
Inflammation research : official journal of the European Histamine Research Society ... [et al.]. 66(1)
Tumor-associated macrophages (TAMs) are key elements in orchestrating host responses inside tumor stroma. This population may undergo a polarized activation process, thus rendering a heterogeneous spectrum of phenotypes, where the classically activat
Autor:
Carolina Añazco, Jacqueline Romero, Fernando Delgado-López, Erik Morales, Armando Rojas, Paulina Araya, Ramón Pérez-Castro, Ileana Gonzalez
Publikováno v:
Biomarkers in medicine. 10(9)
Gastric cancer (GC) is the fifth most frequent cancer in the world and shows the highest incidence in Latin America and Asia. An increasing amount of evidence demonstrates that lysyl oxidase isoforms, a group of extracellular matrix crosslinking enzy