Zobrazeno 1 - 10
of 138
pro vyhledávání: '"Carolina, Soriano"'
Autor:
Joan Jiménez-Balado, Isabel Fernández-Pérez, Cristina Gallego-Fábrega, Uxue Lazcano, Carolina Soriano-Tárraga, Marta Vallverdú-Prats, Marina Mola-Caminal, Lucía Rey-Álvarez, Adrià Macias-Gómez, Antoni Suárez-Pérez, Eva Giralt-Steinhauer, Ana Rodríguez-Campello, Elisa Cuadrado-Godia, Ángel Ois, Manel Esteller, Jaume Roquer, Israel Fernández-Cadenas, Jordi Jiménez-Conde
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-13 (2024)
Abstract Background and aims Stroke is the leading cause of adult-onset disability. Although clinical factors influence stroke outcome, there is a significant variability among individuals that may be attributed to genetics and epigenetics, including
Externí odkaz:
https://doaj.org/article/3f0b1b34c1ca432b9a498408bb37c80e
Autor:
Aina Medina-Dols, Guillem Cañellas, Toni Capó, Montse Solé, Marina Mola-Caminal, Natalia Cullell, Marina Jaume, Laura Nadal-Salas, Jaume Llinàs, Lluis Gómez, Silvia Tur, Carmen Jiménez, Rosa M. Díaz, Caty Carrera, Elena Muiño, Cristina Gallego-Fabrega, Carolina Soriano-Tárraga, Laura Ruiz-Guerra, Josep Pol-Fuster, Víctor Asensio, Josep Muncunill, Aarne Fleischer, Amanda Iglesias, Eva Giralt-Steinhauer, Uxue Lazcano, Isabel Fernández-Pérez, Joan Jiménez-Balado, Marina Gabriel-Salazar, Miguel Garcia-Gabilondo, Ting Lei, Nuria-Paz Torres-Aguila, Jara Cárcel-Márquez, Jerònia Lladó, Gabriel Olmos, Anna Rosell, Joan Montaner, Anna M. Planas, Raquel Rabionet, Mar Hernández-Guillamon, Jordi Jiménez-Conde, Israel Fernández-Cadenas, Cristòfol Vives-Bauzá
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-13 (2024)
Abstract Through GWAS studies we identified PATJ associated with functional outcome after ischemic stroke (IS). The aim of this study was to determine PATJ role in brain endothelial cells (ECs) in the context of stroke outcome. PATJ expression analys
Externí odkaz:
https://doaj.org/article/a3a6afd055e1410284b6f07d9b5f4bf3
Autor:
Abdallah M Eteleeb, Brenna C Novotny, Carolina Soriano Tarraga, Christopher Sohn, Eliza Dhungel, Logan Brase, Aasritha Nallapu, Jared Buss, Fabiana Farias, Kristy Bergmann, Joseph Bradley, Joanne Norton, Jen Gentsch, Fengxian Wang, Albert A Davis, John C Morris, Celeste M Karch, Richard J Perrin, Bruno A Benitez, Oscar Harari
Publikováno v:
PLoS Biology, Vol 22, Iss 4, p e3002607 (2024)
Unbiased data-driven omic approaches are revealing the molecular heterogeneity of Alzheimer disease. Here, we used machine learning approaches to integrate high-throughput transcriptomic, proteomic, metabolomic, and lipidomic profiles with clinical a
Externí odkaz:
https://doaj.org/article/c71d7c799edd465daeb99f4beb049d3a
Autor:
Hao Peng, Helena Palma-Gudiel, Carolina Soriano-Tarraga, Jordi Jimenez-Conde, Mingzhi Zhang, Yonghong Zhang, Jinying Zhao
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-15 (2023)
Abstract Background DNA methylation has previously been associated with ischemic stroke, but the specific genes and their functional roles in ischemic stroke remain to be determined. Here we aimed to identify differentially methylated genes that play
Externí odkaz:
https://doaj.org/article/704968f9ed744dce92bc825a83149d2b
Autor:
Logan Brase, Shih-Feng You, Ricardo D’Oliveira Albanus, Jorge L. Del-Aguila, Yaoyi Dai, Brenna C. Novotny, Carolina Soriano-Tarraga, Taitea Dykstra, Maria Victoria Fernandez, John P. Budde, Kristy Bergmann, John C. Morris, Randall J. Bateman, Richard J. Perrin, Eric McDade, Chengjie Xiong, Alison M. Goate, Martin Farlow, Dominantly Inherited Alzheimer Network (DIAN), Greg T. Sutherland, Jonathan Kipnis, Celeste M. Karch, Bruno A. Benitez, Oscar Harari
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Genetic studies of Alzheimer disease (AD) have prioritized variants in genes related to the amyloid cascade, lipid metabolism, and neuroimmune modulation. However, the cell-specific effect of variants in these genes is not fully understood.
Externí odkaz:
https://doaj.org/article/7041e0b0389849e49d987eee932c41c5
Akademický článek
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Autor:
Isabel Fernández-Pérez, Joan Jiménez-Balado, Uxue Lazcano, Eva Giralt-Steinhauer, Lucía Rey Álvarez, Elisa Cuadrado-Godia, Ana Rodríguez-Campello, Adrià Macias-Gómez, Antoni Suárez-Pérez, Anna Revert-Barberá, Isabel Estragués-Gázquez, Carolina Soriano-Tarraga, Jaume Roquer, Angel Ois, Jordi Jiménez-Conde
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 2759 (2023)
Age acceleration (Age-A) is a useful tool that is able to predict a broad range of health outcomes. It is necessary to determine DNA methylation levels to estimate it, and it is known that Age-A is influenced by environmental, lifestyle, and vascular
Externí odkaz:
https://doaj.org/article/58943a1bd5c44a8995322f47175dc7b8
Autor:
Carolina Soriano-Tárraga, Uxue Lazcano, Eva Giralt-Steinhauer, Carla Avellaneda-Gómez, Ángel Ois, Ana Rodríguez-Campello, Elisa Cuadrado-Godia, Alejandra Gómez-González, Alba Fernández-Sanlés, Roberto Elosua, Israel Fernández-Cadenas, Natalia Cullell, Joan Montaner, Sebastian Moran, Manel Esteller, Jordi Jiménez-Conde, Jaume Roquer
Publikováno v:
Epigenetics, Vol 15, Iss 9, Pp 988-997 (2020)
DNA methylation is dynamic, varies throughout the life course, and its levels are influenced by lifestyle and environmental factors, as well as by genetic variation. The leading genetic variants at stroke risk loci identified to date explain roughly
Externí odkaz:
https://doaj.org/article/cd7b5cf0052944f88b5bb2e56eef03c4
Autor:
Joan Jiménez-Balado, Eva Giralt-Steinhauer, Isabel Fernández-Pérez, Lucía Rey, Elisa Cuadrado-Godia, Ángel Ois, Ana Rodríguez-Campello, Carolina Soriano-Tárraga, Uxue Lazcano, Adrià Macias-Gómez, Antoni Suárez-Pérez, Anna Revert, Isabel Estragués, Brigitte Beltrán-Mármol, Santiago Medrano-Martorell, Jaume Capellades, Jaume Roquer, Jordi Jiménez-Conde
Publikováno v:
Biology, Vol 12, Iss 1, p 33 (2022)
In this manuscript we studied the relationship between WMH and biological age (B-age) in patients with acute stroke. We included in this study 247 patients with acute stroke recruited at Hospital del Mar having both epigenetic (DNA methylation) and m
Externí odkaz:
https://doaj.org/article/6a31d6b532224b41a62052d0a99e1b3f
Autor:
Angel Ois, Elisa Cuadrado-Godia, Eva Giralt-Steinhauer, Jordi Jimenez-Conde, Carolina Soriano-Tarraga, Ana Rodríguez-Campello, Carla Avellaneda, Diego Cascales, Isabel Fernandez-Perez, Jaume Roquer
Publikováno v:
Journal of Stroke, Vol 21, Iss 2, Pp 184-189 (2019)
Background and Purpose To analyze long-term stroke recurrence (SR) characteristics after transient ischemic attack (TIA) according to initial etiological classification. Methods A prospective cohort of 706 TIA patients was followed up in a single ter
Externí odkaz:
https://doaj.org/article/8be0df7a24d443c289952a0a48e041eb