Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Carolin T Haas"'
Autor:
Jack Robertson, Laetitia C. Pele, Juan C. Hernández-Garrido, Rachel E. Hewitt, Nuno Jorge Rodrigues Faria, Helen F. Chappell, Andy Brown, Jeremy N. Skepper, Jonathan J. Powell, Paul A. Midgley, Carolin T Haas
Publikováno v:
Nanomedicine
Amorphous magnesium-substituted calcium phosphate (AMCP) nanoparticles (75-150 nm) form constitutively in large numbers in the mammalian gut. Collective evidence indicates that they trap and deliver luminal macromolecules to mucosal antigen presentin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22bd3e00b9f852e7ed40f2e8791990be
https://doi.org/10.1016/j.nano.2016.07.008
https://doi.org/10.1016/j.nano.2016.07.008
Autor:
Geoffrey W. Grime, Andy Brown, Richard P. H. Thompson, David S. Donaldson, Karen J. Kirkby, I. Gomez-Morilla, Carolin T Haas, Neil A. Mabbott, Daniel Rios, Yakup Tanriver, Ifor R. Williams, Robert I. Lechler, Jeremy N. Skepper, Jack Robertson, Rachel E. Hewitt, Jonathan J. Powell, Giovanna Lombardi, Vinay Thoree, Paul A. Midgley, Emma Thomas-Mckay, Juan C. Hernández-Garrido, Sylvaine Francoise Aline Bruggraber, Jon D. Laman, Stephen E. Girardin, Laetitia C. Pele
Publikováno v:
Nature Nanotechnology, 10(4), 361-369. Nature Publishing Group
Nature nanotechnology
Nature nanotechnology
In humans and other mammals it is known that calcium and phosphate ions are secreted from the distal small intestine into the lumen. However, why this secretion occurs is unclear. Here, we show that the process leads to the formation of amorphous mag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::806abb78c8eaa10f528cb5abf16cc92f
https://doi.org/10.1038/nnano.2015.19
https://doi.org/10.1038/nnano.2015.19
Naturally occurring intestinal nanomineral particles constituently form in the mammalian gut and trap luminal protein and microbial components. These cargo loaded nanominerals are actively scavenged by M cells of intestinal immune follicles, such as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0433bf9a3e006a2de6d1f3c6dc690aa5
Publikováno v:
Frontiers in Immunology
Naturally occurring intestinal nanomineral particles constituently form in the mammalian gut and trap luminal protein and microbial components. These cargo loaded nanominerals are actively scavenged by M cells of intestinal immune follicles, such as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1e9749587e71c975d8a5fb4b0a669d63
https://pubmed.ncbi.nlm.nih.gov/28367148
https://pubmed.ncbi.nlm.nih.gov/28367148
Autor:
Rhiannon, Kundu, Aikaterini, Theodoraki, Carolin T, Haas, Yanjing, Zhang, Benjamin, Chain, Janos, Kriston-Vizi, Mahdad, Noursadeghi, Bernard, Khoo
Publikováno v:
Immunology
Summary Vitamin D is widely reported to inhibit innate immune signalling and dendritic cell (DC) maturation as a potential immunoregulatory mechanism. It is not known whether vitamin D has global or gene‐specific effects on transcriptional response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1c0816e89698cf47e7220fe6c24995e4
https://pubmed.ncbi.nlm.nih.gov/27608289
https://pubmed.ncbi.nlm.nih.gov/27608289
Autor:
Laetitia C. Pele, Carolin T Haas, Jonathan J. Powell, Tom P. Monie, Charles Charalambos, Jack Robertson, Rachel E. Hewitt, Miles Parkes
Publikováno v:
Scientific Reports
Crohn’s disease is a chronic inflammatory condition most commonly affecting the ileum and colon. The aetiology of Crohn’s disease is complex and may include defects in peptidoglycan recognition, and/or failures in the establishment of intestinal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e3abf202a82dee5dbbff329ca7772a8
Publikováno v:
Rheumatology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5491dd50d01bf9e2c1d6d06d4b4cfbf4
https://doi.org/10.1093/rheumatology/kew176
https://doi.org/10.1093/rheumatology/kew176
Publikováno v:
BMC Medicine
The decision to treat active tuberculosis (TB) is dependent on microbiological tests for the organism or evidence of disease compatible with TB in people with a high demographic risk of exposure. The tuberculin skin test and peripheral blood interfer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b30307251b47c530d2a34a718c53212
https://doi.org/10.1186/s12916-016-0583-9
https://doi.org/10.1186/s12916-016-0583-9
Autor:
Christopher Thrasivoulou, David L. Becker, Sarah S. Zaher, Thabo Lapp, Daniel F P Larkin, Carolin T. Haas, Benjamin M. Chain, Mahdad Noursadeghi
Publikováno v:
Investigative ophthalmologyvisual science. 56(12)
Purpose We sought to test the hypothesis that monocytes contribute to the immunopathogenesis of corneal allograft rejection and identify therapeutic targets to inhibit monocyte recruitment. Methods Monocytes and proinflammatory mediators within anter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0088d7d15ed34982f8dedb77780ca95
https://pubmed.ncbi.nlm.nih.gov/26544793
https://pubmed.ncbi.nlm.nih.gov/26544793
Autor:
Laetitia C. Pele, Nuno Jorge Rodrigues Faria, Carolin T Haas, Rachel E. Hewitt, Jonathan J. Powell, Andy Brown
Aim: To determine whether in vitro experimental conditions dictate cellular activation of the inflammasome by apatitic calcium phosphate nanoparticles. Material & methods: The responses of blood-derived primary human cells to in situ-formed apatite w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f5d9b8ab68218a090c82aab194685f0
https://www.repository.cam.ac.uk/handle/1810/295096
https://www.repository.cam.ac.uk/handle/1810/295096