Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Carolin Möckel"'
Autor:
Corinna Weber-Sparenberg, Heinrich Jung, Petra Pöplau, Heiner Brookman, Carolin Möckel, Maike Rochon, Monika Nietschke
Publikováno v:
Archives of Microbiology. 186:307-316
Transport of flagellar structural proteins beyond the cytoplasmic membrane is accomplished by a type III secretory pathway [flagellar type III secretion system (fTTSS)]. The mechanism of substrate recognition by the fTTSS is still enigmatic. Using th
Publikováno v:
Nucleic Acids Research
DNA double-strand breaks (DSBs) threaten genome stability in all kingdoms of life and are linked to cancerogenic chromosome aberrations in humans. The Mre11:Rad50 (MR) complex is an evolutionarily conserved complex of two Rad50 ATPases and a dimer of
Autor:
Katja Sträßer, Sophia Hartung, Carolin Möckel, Emanuel Clausing, Derk J. Bemeleit, María Lucas, Christian B. Schiller, Alexandra Schele, Karl-Peter Hopfner, Katja Lammens, Christof Angermüller, Johannes Söding
Publikováno v:
Cell
Cell 145, 54-66 (2011). doi:10.1016/j.cell.2011.02.038
Cell 145, 54-66 (2011). doi:10.1016/j.cell.2011.02.038
Summary The MR ( M re11 nuclease and R ad50 ABC ATPase) complex is an evolutionarily conserved sensor for DNA double-strand breaks, highly genotoxic lesions linked to cancer development. MR can recognize and process DNA ends even if they are blocked