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pro vyhledávání: '"Carolin Lüking"'
Autor:
Martin Röcken, Elfriede Nößner, Carolin Lüking, Konrad Kronenberger, Ralph Mocikat, Bernhard Frankenberger
Publikováno v:
International Journal of Cancer. 122:2280-2285
Tumor-specific T cells are crucial for immunologic control of malignant disease. T cells can be induced in vivo by vaccination or adoptively transferred after activation ex vivo. We investigated the requirements for generating T cells with optimal an
Autor:
Carolin Lüking, Josef Mysliwietz, Ralph Mocikat, Martin Röcken, Thomas Allgeier, Susan King, Heidi Braumüller, Anja Kriegeskorte, Dirk H. Busch, Christian Adam
Publikováno v:
Blood. 106(1)
It is generally accepted that priming of antitumor CD8+ cytotoxic T lymphocytes (CTLs) needs help that can be provided by CD4+ T cells. We show that interactions between dendritic cells (DCs) and natural killer (NK) cells can bypass the T helper arm