Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Carolin K Koss"'
Autor:
David Kind, Praveen Baskaran, Fidel Ramirez, Martin Giner, Michael Hayes, Diana Santacruz, Carolin K. Koss, Karim C. el Kasmi, Bhagya Wijayawardena, Coralie Viollet
Publikováno v:
SLAS Technology, Vol 27, Iss 2, Pp 135-142 (2022)
Next-generation sequencing (NGS) has revolutionized genomics, decreasing sequencing costs and allowing researchers to draw correlations between diseases and DNA or RNA changes. Technical advances have enabled the analysis of RNA expression changes be
Externí odkaz:
https://doaj.org/article/446dbb9790314867b3b4a9a1f0e0d35c
Autor:
Jonathan R. Baker, Peter S. Fenwick, Carolin K. Koss, Harriet B. Owles, Sarah L. Elkin, Jay Fine, Matthew Thomas, Karim C. El Kasmi, Peter J. Barnes, Louise E. Donnelly
Publikováno v:
JCI Insight, Vol 7, Iss 15 (2022)
Current treatments fail to modify the underlying pathophysiology and disease progression of chronic obstructive pulmonary disease (COPD), necessitating alternative therapies. Here, we show that COPD subjects have increased IL-36γ and decreased IL-36
Externí odkaz:
https://doaj.org/article/bfbbfa894e21493c8e3cf8438e35c9e1
Autor:
Carolin K. Koss, Christian T. Wohnhaas, Jonathan R. Baker, Cornelia Tilp, Michèl Przibilla, Carmen Lerner, Silvia Frey, Martina Keck, Cara M. M. Williams, Daniel Peter, Meera Ramanujam, Jay Fine, Florian Gantner, Matthew Thomas, Peter J. Barnes, Louise E. Donnelly, Karim C. El Kasmi
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Carolin Koss et al. show that IL-36 produced from neutrophils is a key amplifier of lung inflammation in mice by activating neutrophils, macrophages and fibroblasts in cooperation with GM-CSF and the viral mimic poly(I:C). This study suggests that ta
Externí odkaz:
https://doaj.org/article/807afab62a534fbbbb0ab4d532e4b447
Autor:
Praveen Baskaran, Bhagya Wijayawardena, Coralie Viollet, Martin Giner, David Kind, Michael Hayes, Diana Santacruz, Carolin K. Koss, Fidel Ramirez, Karim C. El Kasmi
Publikováno v:
SLAS technology. 27(2)
Next-generation sequencing (NGS) has revolutionized genomics, decreasing sequencing costs and allowing researchers to draw correlations between diseases and DNA or RNA changes. Technical advances have enabled the analysis of RNA expression changes be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::141bdb5f93c9bd693bc61623558e7a22
https://pubmed.ncbi.nlm.nih.gov/35058211
https://pubmed.ncbi.nlm.nih.gov/35058211
Autor:
Stefanie Dichtl, David E Sanin, Carolin K Koss, Sebastian Willenborg, Andreas Petzold, Maria C Tanzer, Andreas Dahl, Agnieszka M Kabat, Laura Lindenthal, Leonie Zeitler, Sabrina Satzinger, Alexander Strasser, Matthias Mann, Axel Roers, Sabine A Eming, Karim C El Kasmi, Edward J Pearce, Peter J Murray
Publikováno v:
Life science alliance
Life Science Alliance
Life Science Alliance
Pro-inflammatory TNF is a highly gene-selective inhibitor of the gene expression program of tissue repair and wound healing macrophages.
Anti-TNF therapies are a core anti-inflammatory approach for chronic diseases such as rheumatoid arthritis a
Anti-TNF therapies are a core anti-inflammatory approach for chronic diseases such as rheumatoid arthritis a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e45144e5db41308cf90fc2f15244db4d
https://hdl.handle.net/21.11116/0000-000D-15D2-E21.11116/0000-000D-15D0-0
https://hdl.handle.net/21.11116/0000-000D-15D2-E21.11116/0000-000D-15D0-0
Autor:
Jonathan R. Baker, Peter S. Fenwick, Carolin K. Koss, Harriet B. Owles, Sarah L. Elkin, Jay Fine, Matthew Thomas, Karim C. El Kasmi, Peter J. Barnes, Louise E. Donnelly
Publikováno v:
JCI insight. 7(15)
Current treatments fail to modify the underlying pathophysiology and disease progression of chronic obstructive pulmonary disease (COPD), necessitating alternative therapies. Here, we show that COPD subjects have increased IL-36γ and decreased IL-36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::059928190bd94e234af850a41c6e36a2
https://pubmed.ncbi.nlm.nih.gov/35763349
https://pubmed.ncbi.nlm.nih.gov/35763349
Autor:
Carolin K. Koss, Peter J. Barnes, Karim El-Kasmi, Jonathan R. Baker, Louise E. Donnelly, Peter Fenwick, Harriet Owles
Publikováno v:
Airway cell biology and immunopathology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4d1358eeffdf8943b84ea5e543e0087
https://doi.org/10.1183/13993003.congress-2021.pa678
https://doi.org/10.1183/13993003.congress-2021.pa678
Autor:
Cornelia Tilp, M.J. Thomas, Katrin Fundel-Clemens, K C El Kasmi, Carmen Lerner, Carolin K. Koss, Peter J. Murray, Daniela Schlösser, Fidel Ramirez, Heinrich J. Huber, Coralie Viollet, Silvia Frey, Wioletta Skronska-Wasek, Florian Gantner, Stefanie Dichtl, Christian T. Wohnhaas
Publikováno v:
12.01 - Idiopathic interstitial pneumonias.
Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive fibrosing interstitial lung disease with poor prognosis. The current standard-of-care for IPF is the kinase inhibitor nintedanib, which has a distinct inhibitory profile targeting a ran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f95b8d3d37521e2f930510d621ce4f8a
https://doi.org/10.1183/23120541.lsc-2021.92
https://doi.org/10.1183/23120541.lsc-2021.92
Autor:
Karim C. El Kasmi, Florian Gantner, Cara M. M. Williams, Silvia Frey, Michèl Przibilla, Meera Ramanujam, Louise E Donnelly, Cornelia Tilp, Carolin K. Koss, Peter J. Barnes, Martina Keck, Jay S. Fine, Daniel Peter, Jonathan R. Baker, Carmen Lerner, M.J. Thomas, Christian T. Wohnhaas
Publikováno v:
Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
IL-36, which belongs to the IL-1 superfamily, is increasingly linked to neutrophilic inflammation. Here, we combined in vivo and in vitro approaches using primary mouse and human cells, as well as, acute and chronic mouse models of lung inflammation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7f46ac5112d428123cf8b853b50701c
https://doi.org/10.1038/s42003-021-01703-3
https://doi.org/10.1038/s42003-021-01703-3