Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Carolin Cornelius"'
Autor:
Christian Lupinek, Kurt Derfler, Silvia Lee, Thomas Prikoszovich, Oliver Movadat, Eva Wollmann, Carolin Cornelius, Milena Weber, Renate Fröschl, Regina Selb, Katharina Blatt, Dubravka Smiljkovic, Volker Schoder, René Cervenka, Thomas Plaichner, Gottfried Stegfellner, Hans Huber, Rainer Henning, Justyna Kozik-Jaromin, Thomas Perkmann, Verena Niederberger, Ventzislav Petkov, Peter Valent, Adelheid Gauly, Hans Peter Leinenbach, Ingrid Uhlenbusch-Koerwer, Rudolf Valenta
Publikováno v:
EBioMedicine, Vol 17, Iss C, Pp 119-133 (2017)
Background: Prevention of IgE-binding to cellular IgE-receptors by anti-IgE (Omalizumab) is clinically effective in allergic asthma, but limited by IgE threshold-levels. To overcome this limitation, we developed a single-use IgE immunoadsorber column
Externí odkaz:
https://doaj.org/article/fc182c7678904540a33c121811dc1d3f
Autor:
Carolin Cornelius, Katrin Schöneweis, Fanny Georgi, Milena Weber, Verena Niederberger, Petra Zieglmayer, Katarzyna Niespodziana, Michael Trauner, Harald Hofer, Stephan Urban, Rudolf Valenta
Publikováno v:
EBioMedicine, Vol 11, Iss C, Pp 58-67 (2016)
Background: We have constructed and clinically evaluated a hypoallergenic vaccine for grass pollen allergy, BM32, which is based on fusion proteins consisting of peptides from the IgE binding sites of the major grass pollen allergens fused to preS (p
Externí odkaz:
https://doaj.org/article/fcc8a1eac2a04fd6b4b45b4135bf769c
Autor:
Patrick Lemell, Inna Tulaeva, Milena Weber, Rainer Henning, Alexander Karaulov, René Zieglmayer, Carolin Cornelius, Petra Zieglmayer, Margarete Focke-Tejkl, Rudolf Valenta, René Schmutz
Publikováno v:
EBioMedicine
Background Chronic hepatitis B virus (HBV) infections are a global health problem. There is a need for therapeutic strategies blocking continuous infection of liver cells. The grass pollen allergy vaccine BM32 containing the preS domain of the large
Autor:
Rosalba Siracusa, Emanuela Esposito, Michela Campolo, Salvatore Cuzzocrea, Irene Paterniti, Marika Cordaro, Michele Navarra, Carolin Cornelius
Publikováno v:
CNS & Neurological Disorders - Drug Targets. 13:1530-1541
Alzheimer's disease (AD) is the most common neurodegenerative disorder. Its neuropathological hallmarks include deposition of beta amyloid (Aβ) fibrils in senile plaques. Numerous biochemical events, leading to Aβ neurotoxicity in AD, have been pro
Autor:
Monika Praschberger, Kathrin Haider, Hans Goldenberg, Brigitte Sturm, Carolin Cornelius, Markus Schitegg, Barbara Scheiber-Mojdehkar
Publikováno v:
BioMetals. 28:35-50
Intravenous iron preparations, like iron sucrose (IS) and ferric carboxymaltose (FCM) differ in their physicochemical stability. Thus differences in storage and utilization can be expected and were investigated in a non-clinical study in liver parenc
Autor:
Fabio Dall’Antonia, Siva Charan Devanaboyina, Andreas Nandy, S. Hagen, Kerstin Fauland, Rudolph Valenta, Sabine Flicker, Christian Lupinek, Walter Keller, Carolin Cornelius
Publikováno v:
Allergy. 69:1617-1628
Background Group 2 and 3 grass pollen allergens are major allergens with high allergenic activity and exhibit structural similarity with the C-terminal portion of major group 1 allergens. In this study, we aimed to determine the crystal structure of
Autor:
Salvatore Cuzzocrea, Vittorio Calabrese, Pietro Milone, Giovanni Pennisi, Antonio Graziano, Zsolt Radak, Carolin Cornelius, Rosalia Crupi, Edward J. Calabrese
Publikováno v:
Antioxidants & Redox Signaling. 19:836-853
A vast amount of circumstantial evidence implicates high energy oxidants and oxidative stress as mediators of secondary damage associated with traumatic brain injury. The excessive production of reactive oxygen species due to excitotoxicity and exhau
Autor:
Alfio Catalano, Carolin Cornelius, Giuseppe Carpinteri, Daniela Modica, Rita Bella, Giuseppe Lanza, Manuela Pennisi, Giovanni Pennisi, Salvatore Giuffrida
Publikováno v:
World Journal of Neuroscience. :53-56
Introduction: Although anemia is not regarded as an usual vascular risk factor for stroke, it is one of the potential mechanism by which the brain does not receive adequate oxygenation. Moreover, the relationship between drop of hemoglobin and acute
Autor:
Albena T. Dinkova-Kostova, Mark P. Mattson, Vittorio Calabrese, Carolin Cornelius, Edward J. Calabrese
Publikováno v:
Antioxidants & Redox Signaling. 13:1763-1811
Despite the capacity of chaperones and other homeostatic components to restore folding equilibrium, cells appear poorly adapted for chronic oxidative stress that increases in cancer and in metabolic and neurodegenerative diseases. Modulation of endog
Autor:
Vittorio Calabrese, Carolin Cornelius, F. Di Domenico, Marzia Perluigi, David Allan Butterfield
Publikováno v:
Neurochemical Research. 35:2184-2192
Aging is characterized by a gradual and continuous loss of physiological functions and responses particularly marked in the central nervous system. Reactive oxygen species (ROS) can react with all major biological macromolecules such as carbohydrates