Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Carolin Bisterfeld"'
Autor:
Carolin Bisterfeld, Thomas Classen, Irene Küberl, Birgit Henßen, Alexander Metz, Holger Gohlke, Jörg Pietruszka
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0156525 (2016)
The 2-deoxy-d-ribose-5-phosphate aldolase (DERA) offers access to highly desirable building blocks for organic synthesis by catalyzing a stereoselective C-C bond formation between acetaldehyde and certain electrophilic aldehydes. DERA´s potential is
Externí odkaz:
https://doaj.org/article/b1c5603e429447429a670caba5849634
Autor:
Meera Haridas, Carolin Bisterfeld, Le Min Chen, Stefan R. Marsden, Fabio Tonin, Rosario Médici, Adolfo Iribarren, Elizabeth Lewkowicz, Peter-Leon Hagedoorn, Ulf Hanefeld, Eman Abdelraheem
Publikováno v:
Catalysts, Vol 10, Iss 883, p 883 (2020)
Catalysts
Volume 10
Issue 8
Catalysts, 10(8)
Catalysts
Volume 10
Issue 8
Catalysts, 10(8)
DERA (2-Deoxy-D-ribose 5-phosphate aldolase) is the only known aldolase that accepts two aldehyde substrates, which makes it an attractive catalyst for the synthesis of a chiral polyol motif that is present in several pharmaceuticals, such as atorvas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13b2c7bfaa380ee507df54647000d5a7
https://www.mdpi.com/2073-4344/10/8/883
https://www.mdpi.com/2073-4344/10/8/883
Autor:
Guzman Torrelo, Nicolas de Leeuw, Verena Resch, Emanuele Straulino, Carolin Bisterfeld, Ulf Hanefeld, Luuk Mestrom, Laura van der Weel
Publikováno v:
Advanced Synthesis & Catalysis. 360:242-249
The acyl transferase from Mycobacterium smegmatis (MsAcT) catalyses transesterification reactions in aqueous media because of its hydrophobic active site. Aliphatic cyanohydrin and alkyne esters can be synthesised in water with excellent and striking
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6dcb37b7e763ba1d15468b7ab6fa967
https://doi.org/10.1002/adsc.201701282
https://doi.org/10.1002/adsc.201701282
Publikováno v:
Nachrichten aus der Chemie. 65:632-635
Hohe Konzentrationen an Acetaldehyd hemmen die Aldolase, das Enzym arbeitet nicht mehr. NMR-Spektroskopie, Rontgenstruktur und biochemische Analysen zeigen, wie es dazu kommt. Und sie offenbaren eine Losung: Wird eine Aminosaure ausgetauscht, ist das
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1b5fe1bc17a409b98968127c9e3289f
https://doi.org/10.1002/nadc.20174055285
https://doi.org/10.1002/nadc.20174055285
The discovery of the first cyclopropyl lactone-containing marine oxylipin in 1981 revealed a new class of compounds with interesting structural motifs exhibiting different bioactive properties. The development of stereodivergent approaches, structura
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33b3521bed8dfee6868d2163ec92acfd
https://doi.org/10.1016/b978-0-444-64068-0.00005-x
https://doi.org/10.1016/b978-0-444-64068-0.00005-x
Publikováno v:
Synlett. 27:11-16
A highly sensitive, fluorescence-based selectivity screening system for 2-deoxy- d -ribose-5-phosphate aldolases was realized by installing short, straightforward syntheses to fluorophore-coupled carbohydrates as d -ribose, l -ribose, and d -xylose.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d0ec0668d45b1f183e3b86265350227
https://doi.org/10.1055/s-0035-1560723
https://doi.org/10.1055/s-0035-1560723
Autor:
Julia Bramski, Alexander Böker, Carolin Bisterfeld, Nane Vanparijs, Bruno G. De Geest, Stefan Reinicke, Jörg Pietruszka, Shuhao Zhang
Publikováno v:
Bioconjugate chemistry. 29(1)
2-Deoxy-D-ribose-5-phosphate aldolase (DERA) is a biocatalyst that is capable of converting acetaldehyde and a second aldehyde as acceptor into enantiomerically pure mono- and diyhydroxyaldehydes, which are important structural motifs in a number of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc78d79e361d610bd1c2071a8a497fd9
https://pubmed.ncbi.nlm.nih.gov/29182313
https://pubmed.ncbi.nlm.nih.gov/29182313
Publikováno v:
Journal of natural products. 80(5)
Different enzymatic and nonenzymatic approaches were tested and compared to afford enantiopure homoallylic and allylic alcohols as building blocks in a total synthesis showcase. Thereby, highly enantioselective alcohol dehydrogenases and the P450 BM3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b424a3c8f696a9bd315dd12abac019e
https://pubmed.ncbi.nlm.nih.gov/28445040
https://pubmed.ncbi.nlm.nih.gov/28445040
Autor:
Markus Dick, Gerald Brezesinski, Pieter Espeel, Filip Du Prez, Carolin Bisterfeld, Stefan Reinicke, Alexander Böker, Huw C. Rees, Nane Vanparijs, Bruno G. De Geest, Ruben R. Rosencrantz, Jörg Pietruszka
Publikováno v:
ACS Applied Materials and Interfaces
A synthetic protocol for the fabrication of ultrathin polymeric films containing the enzyme 2-deoxy-Dribose- 5-phosphate aldolase from Escherichia coli (DERAEC) is presented. Ultrathin enzymatically active films are useful for applications in which o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4df077be7bf935fe3bfa16d0c4a83a6
https://publica.fraunhofer.de/handle/publica/250790
https://publica.fraunhofer.de/handle/publica/250790
Autor:
Julia Bramski, Carolin Bisterfeld, Holger Gohlke, Thomas Classen, Markus Dick, Jörg Pietruszka, Oliver H. Weiergräber
Publikováno v:
Scientific Reports. 6
Scientific Reports 6: Article number: 17908; published online: 19 January 2016; updated: 11 November 2016
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19c09c52e5d1f24f69cbc9164c39fad1
https://doi.org/10.1038/srep36431
https://doi.org/10.1038/srep36431