Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Carolin Beuker"'
Autor:
Frederike A. Straeten, Jan-Kolja Strecker, Anna-Lena Börsch, Bastian Maus, Maike Hoppen, Birgit Schmeddes, Lucia Härtel, Ann-Katrin Fleck, Stephanie van Zyl, Tabea Straeten, Carolin Beuker, Mailin Koecke, Louisa Mueller-Miny, Cornelius Faber, Gerd Meyer zu Hörste, Luisa Klotz, Jens Minnerup, Antje Schmidt-Pogoda
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
BackgroundA dietary supplementation with conjugated linoleic acid (CLA) was shown to attenuate inflammation and increase the proportions of circulating regulatory T cells (Tregs) and M2-type macrophages in disease models such as autoimmune encephalit
Externí odkaz:
https://doaj.org/article/2305f50d3f624403be9dc53471fd871e
Autor:
Antje Schmidt-Pogoda, Johannes Kaesmacher, Nadine Bonberg, Nils Werring, Jan-Kolja Strecker, Mailin Hannah Marie Koecke, Carolin Beuker, Jan Gralla, Raphael Meier, Heinz Wiendl, Heike Minnerup, Urs Fischer, Jens Minnerup
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
BackgroundThe “translational roadblock” between successful animal stroke studies and neutral clinical trials is usually attributed to conceptual weaknesses. However, we hypothesized that rodent studies cannot inform the human disease due to intri
Externí odkaz:
https://doaj.org/article/c80e9d48620c41b7b9336f7dd2b2707c
Autor:
Mailin Hannah Marie Koecke, Jan‐Kolja Strecker, Frederike Anne Straeten, Carolin Beuker, Jens Minnerup, Antje Schmidt‐Pogoda
Publikováno v:
Brain and Behavior, Vol 14, Iss 3, Pp n/a-n/a (2024)
Abstract Aims To distinguish between the genuine cellular impact of the ischemic cascade by leukocytes and unspecific effects of edema and humoral components, two knock‐in mouse lines were utilized. Mouse lines Y731F and Y685F possess point mutatio
Externí odkaz:
https://doaj.org/article/34c106f181b74174bf5453a29971335d
Autor:
Peter B. Sporns, André Kemmling, Lennart Meyer, Christos Krogias, Volker Puetz, Kolja M. Thierfelder, Marco Duering, Carsten Lukas, Daniel Kaiser, Sönke Langner, Alex Brehm, Lukas T. Rotkopf, Wolfgang G. Kunz, Carolin Beuker, Walter Heindel, Jens Fiehler, Peter Schramm, Heinz Wiendl, Heike Minnerup, Marios Nikos Psychogios, Jens Minnerup
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
Background and purposeAutomated perfusion imaging can detect stroke patients with unknown time of symptom onset who are eligible for thrombolysis. However, the availability of this technique is limited. We, therefore, established the novel concept of
Externí odkaz:
https://doaj.org/article/aadc193dd449416f8565b01f9a71be7b
Autor:
Louisa Müller-Miny, Raoul Sauer, Andreas Schulte-Mecklenbeck, Catharina C. Gross, Stjepana Kovac, Matthias Schilling, Carolin Beuker, Heinz Wiendl, Gerd Meyer zu Hörste
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 16 (2023)
Autoantibodies against contactin-associated protein 2 (CASPR2) are usually associated with autoimmune encephalitis and neuromyotonia. Their association with inflammatory neuropathies has been described in case reports albeit all with distal symmetric
Externí odkaz:
https://doaj.org/article/67d22573ef5f4d45a4205efa98b0d812
Autor:
Carolin Beuker, David Schafflick, Jan-Kolja Strecker, Michael Heming, Xiaolin Li, Jolien Wolbert, Antje Schmidt-Pogoda, Christian Thomas, Tanja Kuhlmann, Irene Aranda-Pardos, Noelia A-Gonzalez, Praveen Ashok Kumar, Yves Werner, Ertugrul Kilic, Dirk M. Hermann, Heinz Wiendl, Ralf Stumm, Gerd Meyer zu Hörste, Jens Minnerup
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
How ischaemic stroke affects the brain borders is not fully understood. Here the authors show that a stroke-associated myeloid cell population occurs exclusively in brain parenchyma that shares features with neurodegenerative microglia and blockade o
Externí odkaz:
https://doaj.org/article/19382b9ff80a421facdf68942549d672
Autor:
Daniel Strunk, Antje Schmidt-Pogoda, Carolin Beuker, Lennart S. Milles, Catharina Korsukewitz, Sven G. Meuth, Jens Minnerup
Publikováno v:
Frontiers in Neurology, Vol 10 (2019)
Besides being affected by the rare and severe primary angiitis of the central nervous system (PACNS) the nervous system is also affected by primary systemic vasculitides (PSV). In contrast to PACNS, PSV affect not only the central but also the periph
Externí odkaz:
https://doaj.org/article/637eeeecf5e04a97a30ccd5c08c63570
Autor:
Carolin Beuker, Antje Schmidt, Daniel Strunk, Peter B. Sporns, Heinz Wiendl, Sven G. Meuth, Jens Minnerup
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 11 (2018)
Primary angiitis of the central nervous system (PACNS) represents a rare inflammatory disease affecting the brain and spinal cord. Stroke, encephalopathy, headache and seizures are major clinical manifestations. The diagnosis of PACNS is based on the
Externí odkaz:
https://doaj.org/article/5e65a593dd8343e4a7afb0b795762af7
Autor:
Frank Hoffmann, Andrea Kraft, Franz Heigl, Erich Mauch, Jürgen Koehler, Lutz Harms, Tania Kümpfel, Wolfgang Köhler, Sven Ehrlich, Antonios Bayas, Julia Weinmann-Menke, Carolin Beuker, Karl-Heinz Henn, Ilya Ayzenberg, Gisa Ellrichmann, Kerstin Hellwig, Reinhard Klingel, Cordula Marie Fassbender, Harald Fritz, Torsten Slowinski, Horst Weihprecht, Marcus Brand, Thomas Stiegler, Jan Galle, Sebastian Schimrigk
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 11 (2018)
Background: Up to every fourth woman with multiple sclerosis (MS) or neuromyelitis optica spectrum disorder (NMOSD) suffers a clinically relevant relapse during pregnancy. High doses of steroids bear some serious risks, especially within the first tr
Externí odkaz:
https://doaj.org/article/ac10befae0934ef09866fb487e90b553
Autor:
Antje Schmidt-Pogoda, Jan-Kolja Strecker, Marie Liebmann, Christina Massoth, Carolin Beuker, Uwe Hansen, Simone König, Sarah Albrecht, Stefanie Bock, Johanna Breuer, Clemens Sommer, Nicholas Schwab, Heinz Wiendl, Luisa Klotz, Jens Minnerup
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0209871 (2018)
Sodium chloride promotes vascular fibrosis, arterial hypertension, pro-inflammatory immune cell polarization and endothelial dysfunction, all of which might influence outcomes following stroke. But despite enormous translational relevance, the functi
Externí odkaz:
https://doaj.org/article/c9179475ce80422e96c1eca14defff9f