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pro vyhledávání: '"Carolin B. Wagner"'
Autor:
Vanessa Borges Pires, Nina Lohner, Tina Wagner, Carolin B. Wagner, Maya Wilkens, Mona Hajikazemi, Katrin Paeschke, Falk Butter, Brian Luke
Publikováno v:
Cell Reports, Vol 42, Iss 2, Pp 112077- (2023)
Summary: At critically short telomeres, stabilized TERRA RNA-DNA hybrids drive homology-directed repair (HDR) to delay replicative senescence. However, even at long- and intermediate-length telomeres, not subject to HDR, transient TERRA RNA-DNA hybri
Externí odkaz:
https://doaj.org/article/9324f7a21b5344ca97c728a2a0a845d6
Publikováno v:
Nucleic Acids Research. 50:12829-12843
Cancer cells achieve immortality by employing either homology-directed repair (HDR) or the telomerase enzyme to maintain telomeres. ALT (alternative lengthening of telomeres) refers to the subset of cancer cells that employ HDR. Many ALT features are
Autor:
Carolin B, Wagner, Brian, Luke
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2528
It has recently been demonstrated that budding yeast telomeres are transcribed into TERRA, a long noncoding RNA. Due to the G-rich nature of the coding strand, TERRA has a tendency to form DNA-RNA hybrids and potentially R-loops, which in turn, promo
Autor:
Max C. Lemme, H. Ulrich Göringer, Christian Damm, Mario Mueh, Robert Knieß, Ulrich Plachetka, Simon Sawallich, Carolin B. Wagner, Bartos Chmielak
Publikováno v:
Frequenz. 72:101-111
Human African trypanosomiasis (HAT) is a neglected tropical disease (NTD) for which adequate therapeutic and diagnostic measures are still lacking. Causative agent of HAT is the African trypanosome, a single-cell parasite, which propagates in the blo