Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Carolin, Gerbeth"'
Autor:
Patrick Shum, Thomas Licher, John L. Kane, Carolin Gerbeth-Kreul, Gerhard Hessler, Antje Pommereau, Sven Ruf, Christian Engel, Linli Wei, Joerg Czech, Theresa A Kuntzweiler
Publikováno v:
SLAS Discovery. 26:783-797
Classical high-throughput screening (HTS) technologies for the analysis of ionic currents across biological membranes can be performed using fluorescence-based, radioactive, and mass spectrometry (MS)-based uptake assays. These assays provide rapid r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44e4fb083c4e35d492c537df0250e79a
https://doi.org/10.1177/24725552211011180
https://doi.org/10.1177/24725552211011180
Autor:
Carolin, Gerbeth-Kreul, Antje, Pommereau, Sven, Ruf, John L, Kane, Theresa, Kuntzweiler, Gerhard, Hessler, Christian K, Engel, Patrick, Shum, LinLi, Wei, Joerg, Czech, Thomas, Licher
Publikováno v:
SLAS discovery : advancing life sciences RD. 26(6)
Classical high-throughput screening (HTS) technologies for the analysis of ionic currents across biological membranes can be performed using fluorescence-based, radioactive, and mass spectrometry (MS)-based uptake assays. These assays provide rapid r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b9160baf68ccf7faf0016023ba5f4dc1
https://pubmed.ncbi.nlm.nih.gov/33955247
https://pubmed.ncbi.nlm.nih.gov/33955247
Autor:
Magdalena Opalińska, Angelika B. Harbauer, Nikolaus Pfanner, Sanjana Rao, Carolin Gerbeth, Oliver Schmidt, Chris Meisinger, Bernard Guiard, Birgit Schönfisch, Josip S. Herman
Publikováno v:
Science. 346:1109-1113
Mitochondria play central roles in cellular energy conversion, metabolism, and apoptosis. Mitochondria import more than 1000 different proteins from the cytosol. It is unknown if the mitochondrial protein import machinery is connected to the cell div
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b60e826a762c20f3456813228fd5929
https://doi.org/10.1126/science.1261253
https://doi.org/10.1126/science.1261253
Autor:
Alexander Martin Heberle, Bettina Warscheid, Birgit Holzwarth, Sara Gelino, Miriam Langelaar-Makkinje, Malene Hansen, Chris Meisinger, Carolin Gerbeth, Ralf Baumeister, Jennifer J. Schwarz, Marcel A. T. M. van Vugt, Kathrin Thedieck, Deepti S. Wilkinson, Stefanie Ruf
Publikováno v:
Autophagy, 13(3), 486-505. Taylor & Francis Group
Autophagy
Autophagy
Mechanistic target of rapamycin complex 1 (MTORC1) and polo like kinase 1 (PLK1) are major drivers of cancer cell growth and proliferation, and inhibitors of both protein kinases are currently being investigated in clinical studies. To date, MTORC1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc92a92c9ce40bfe02f955479d1c2a34
https://research.rug.nl/en/publications/7e875278-2318-4f08-bfda-6538fdaa4f66
https://research.rug.nl/en/publications/7e875278-2318-4f08-bfda-6538fdaa4f66
Autor:
Chris Meisinger, Kaitlin E. Samocha, Prathapan Thiru, Jiahai Shi, M. Michael Harden, Nora F. Vögtle, Jürgen Ruland, Rui Song, Aliakbar Shahsafaei, Wendy Salmon, George W. Bell, Yoav D. Shaul, Marko Knoll, Harvey F. Lodish, Daniel G. MacArthur, Matthew P. Stokes, Jeffrey C. Silva, Cynthia Chen, Heide Christine Patterson, Cher X. Huang, Carolin Gerbeth, Jennifer Kao
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 113(14)
Reactive oxygen species (ROS) such as hydrogen peroxide (H2O2) govern cellular homeostasis by inducing signaling. H2O2 modulates the activity of phosphatases and many other signaling molecules through oxidation of critical cysteine residues, which le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f569b1ccac5159e8d193a428943dee19
https://pubmed.ncbi.nlm.nih.gov/26438848
https://pubmed.ncbi.nlm.nih.gov/26438848
Autor:
Jiahai Shi, Nora F. Vögtle, Marko Knoll, Harvey F. Lodish, Kaitlin E. Samocha, Cynthia Chen, Daniel G. MacArthur, Heide Christine Patterson, Prathapan Thiru, George W. Bell, Cher X. Huang, Carolin Gerbeth, Jennifer Kao, Yoav D. Shaul, Chris Meisinger, Aliakbar Shahsafaei, Jürgen Ruland, Rui Song, Wendy Salmon, M. Michael Harden, Matthew P. Stokes, Jeffrey C. Silva
Publikováno v:
Proceedings of the National Academy of Sciences. 112
Reactive oxygen species (ROS) such as hydrogen peroxide (H2O2) govern cellular homeostasis by inducing signaling. H2O2 modulates the activity of phosphatases and many other signaling molecules through oxidation of critical cysteine residues, which le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c989a88c9e8fafb49a5bb5fbcf799607
https://doi.org/10.1073/pnas.1517932112
https://doi.org/10.1073/pnas.1517932112
Autor:
Angelika B, Harbauer, Magdalena, Opalińska, Carolin, Gerbeth, Josip S, Herman, Sanjana, Rao, Birgit, Schönfisch, Bernard, Guiard, Oliver, Schmidt, Nikolaus, Pfanner, Chris, Meisinger
Publikováno v:
Science (New York, N.Y.). 346(6213)
Mitochondria play central roles in cellular energy conversion, metabolism, and apoptosis. Mitochondria import more than 1000 different proteins from the cytosol. It is unknown if the mitochondrial protein import machinery is connected to the cell div
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::76b14721da1a26f9aab97e97ed7f8b80
https://pubmed.ncbi.nlm.nih.gov/25602310
https://pubmed.ncbi.nlm.nih.gov/25602310
Publikováno v:
The FEBS journal. 280(20)
For decades, the pyruvate dehydrogenase complex in the mitochondrial matrix was considered as a rare example of how protein kinases and phosphatases can regulate important functions within this organelle. During the last decade, several proteomic stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eeb4d58e8162bd5ce7c5d4ecf7d69864
https://pubmed.ncbi.nlm.nih.gov/23895388
https://pubmed.ncbi.nlm.nih.gov/23895388
Autor:
Sanjana Rao, Angelika B. Harbauer, Despina Mikropoulou, Carolin Gerbeth, Chris Meisinger, Oliver Schmidt
Publikováno v:
Cell cycle (Georgetown, Tex.). 10(13)
Protein import into mitochondria is an essential process in every eukaryotic organism. While most of the components of the import machinery have been identified and are mechanistically quite well understood, regulation of this process had been a larg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1d5db41d94ebdc8ce56cb2f368498ab
https://pubmed.ncbi.nlm.nih.gov/21606678
https://pubmed.ncbi.nlm.nih.gov/21606678
Autor:
Nikolaus Pfanner, Despina Mikropoulou, Oliver Schmidt, Bernard Guiard, Angelika B. Harbauer, Magdalena Opalińska, Carolin Gerbeth, Chris Meisinger, Sanjana Rao
Publikováno v:
Cell Metabolism. (4):578-587
SummaryMost mitochondrial proteins are imported by the translocase of the outer mitochondrial membrane (TOM). Tom22 functions as central receptor and transfers preproteins to the import pore. Casein kinase 2 (CK2) constitutively phosphorylates the cy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee6af602baa56f0eb7240f1b0a2f73d2