Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Carolien H.M. Versantvoort"'
Autor:
Agnes G. Oomen, Esther F.A. Brandon, Carolien H.M. Versantvoort, Adriënne J.A.M. Sips, Jacqueline van Engelen, Cathy J.M. Rompelberg
Publikováno v:
Regulatory Toxicology and Pharmacology. 44:161-171
This paper describes the applicability of in vitro digestion models as a tool for consumer products in (ad hoc) risk assessment. In current risk assessment, oral bioavailability from a specific product is considered to be equal to bioavailability fou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b284ae4c813cdb0e9fc5349140439686
https://doi.org/10.1016/j.yrtph.2005.10.002
https://doi.org/10.1016/j.yrtph.2005.10.002
Autor:
Adriënne J.A.M. Sips, Agnes G. Oomen, Erwin Van de Kamp, Cathy J.M. Rompelberg, Carolien H.M. Versantvoort
Publikováno v:
Food and Chemical Toxicology. 43:31-40
Food is considered a major route of exposure to many contaminants. Only the fraction of the contaminant that is released from the food (bioaccessibility) and is bioavailable can exert toxic effects. Insufficient knowledge on the bioavailability may h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e32d88cabd2ad3d97f4a619c634bdbd
https://doi.org/10.1016/j.fct.2004.08.007
https://doi.org/10.1016/j.fct.2004.08.007
Autor:
Adriënne J.A.M. Sips, H.E.M.G. Haenen, Carolien H.M. Versantvoort, Gerrit Wolterink, J.G.M. van Engelen, L.L. de Zwart
Publikováno v:
Regulatory Toxicology and Pharmacology. 39:282-309
Whether children incur different risks from xenobiotics than adults will depend on the exposure, biokinetics, and dynamics of compound. In this paper, current knowledge on developmental physiology and possible effects on biokinetics are evaluated and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa978e8fc3c3544defffc638ef1d93fb
https://doi.org/10.1016/j.yrtph.2004.02.006
https://doi.org/10.1016/j.yrtph.2004.02.006
Autor:
Rob C.A Ondrewater, Andries J Gilde, Carolien H.M Versantvoort, John P. Groten, Erwin Duizer, Johannes J.M. van de Sandt
Publikováno v:
Environmental toxicology and pharmacology. 11(3-4)
Purpose: previous studies have shown that the rat small intestinal cell line IEC-18 provides a size-selective barrier for paracellularly transported hydrophilic macromolecules. In order to determine the utility of IEC-18 cells as an in vitro model to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3485e42db1eb33c29293a407b164320b
https://pubmed.ncbi.nlm.nih.gov/21782616
https://pubmed.ncbi.nlm.nih.gov/21782616
Effects of cadmium chloride on the paracellular barrier function of intestinal epithelial cell lines
Publikováno v:
Toxicology and applied pharmacology. 155(2)
In the present study we characterized the functional and structural disruption of the paracellular barrier of intestinal epithelium in vitro in relation to cytotoxicity after apical Cd2+ exposure. For that purpose filter-grown Caco-2 and IEC-18 cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb72d4252879caae06db58ea1fb73231
https://pubmed.ncbi.nlm.nih.gov/10053166
https://pubmed.ncbi.nlm.nih.gov/10053166
Autor:
Rob C.A Ondrewater, Andries J Gilde, Carolien H.M Versantvoort, Johannes J.M. van de Sandt, John P. Groten, Erwin Duizer
Publikováno v:
Environmental Toxicology and Pharmacology. 13:55
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57a7e854294bd6e258f5208b19361480
https://doi.org/10.1016/s1382-6689(02)00123-0
https://doi.org/10.1016/s1382-6689(02)00123-0