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of 3
pro vyhledávání: '"Carolien Bastiaanssen"'
Autor:
Carolien Bastiaanssen, Pilar Bobadilla Ugarte, Kijun Kim, Giada Finocchio, Yanlei Feng, Todd A. Anzelon, Stephan Köstlbacher, Daniel Tamarit, Thijs J. G. Ettema, Martin Jinek, Ian J. MacRae, Chirlmin Joo, Daan C. Swarts, Fabai Wu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Argonaute proteins are the central effectors of RNA-guided RNA silencing pathways in eukaryotes, playing crucial roles in gene repression and defense against viruses and transposons. Eukaryotic Argonautes are subdivided into two clades: AGOs
Externí odkaz:
https://doaj.org/article/00119b4a7cf949e3816963ef58da50a7
Publikováno v:
Biophysical Journal. 122:305a
Autor:
Carolien Bastiaanssen, Kijun Kim, Young-Yoon Lee, Haedong Kim, V. Narry Kim, S. Chan Baek, Jeesoo Kim
Publikováno v:
Molecular cell. 81(16)
Summary Maturation of canonical microRNA (miRNA) is initiated by DROSHA that cleaves the primary transcript (pri-miRNA). More than 1,800 miRNA loci are annotated in humans, but it remains largely unknown whether and at which sites pri-miRNAs are clea