Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Carole S. Watson"'
Publikováno v:
Endocrinology. 147:1175-1186
IGF binding protein-1 (IGFBP-1) inhibits the mitogenic actions of the IGFs. Circulating IGFBP-1 is elevated in newborns and experimental animals with fetal growth restriction (FGR). To establish a causal relationship between high circulating IGFBP-1
Autor:
Carole S. Watson, A. D. Bocking, Richard Harding, Donald H. Penning, Sandra Rees, James D. Reynolds, Michelle Loeliger
Publikováno v:
Neuroscience. 116:705-714
Umbilical cord occlusion causes fetal hypoxemia which can result in brain injury including damage to cerebral white matter. Excessive glutamate release may be involved in the damage process. This study examined the relation between extracellular glut
Autor:
Susan E. White, Alan D. Bocking, Jacobus H. Homan, Karen A. Kimura, Laurence J. Fraher, Carole S. Watson, John R. G. Challis, James F. Brien
Publikováno v:
Journal of Applied Physiology. 86:1410-1420
Adenosine and PGE2are neuromodulators, both of which inhibit fetal breathing movements (FBM). Although circulating PGE2has been implicated as a mediator of ethanol-induced inhibition of FBM in the late-gestation ovine fetus, a role for adenosine has
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 76:858-866
Fetal breathing movements (FBM) are inhibited by both exogenous prostaglandin E2 (PGE2) and ethanol in sheep. Maternal ethanol exposure in late-gestation sheep also increases fetal [PGE2]. However, during prolonged reduced uterine blood flow (RUBF) w
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 76:858-866
Autor:
Susan E. White, Carole S. Watson, J. Homan, A. D. Bocking, S. Abdollah, John R. G. Challis, James F. Brien
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 74:1016-1024
Lorsqu'une hypoxemie prolongee est induite chez la brebis foetale suite a une reduction du debit sanguin uterin (RDSU), les mouvements respiratoires foetaux (MRF) diminuent d'abord pour revenir ensuite a la valeur normale. L'ethanol inhibe aussi les
Autor:
Julie L.V. Shaw, Eleftherios P. Diamandis, Constantina Petraki, Carole S. Watson, Alan D. Bocking
Publikováno v:
Biological chemistry. 389(12)
Human tissue kallikrein-related peptidases (KLKs) are 15 hormonally regulated genes on chromosome 19q13.4 encoding secreted serine proteases. Many KLKs are expressed throughout the female reproductive system and found in cervico-vaginal fluid (CVF).
Autor:
Alan D. Bocking, Sarah Keating, Rose M. Rizek, John R. G. Challis, Carole S. Watson, Hsin-Hsiung Tai
Publikováno v:
Reproductive sciences (Thousand Oaks, Calif.). 14(3)
Prostaglandins play a central role in the stimulation and maintenance of both term and preterm labor. 15-Hydroxyprostaglandin dehydrogenase (PGDH), localized primarily to chorion trophoblasts, is the key enzyme responsible for the metabolism of prost
Autor:
Rose M. Rizek, Nadeen Edmondson, Alan Bocking, Sarah Keating, Carole S. Watson, Geoffrey Machin
Publikováno v:
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society. 12(1)
Preterm labor is a major cause of perinatal mortality and morbidity, and in approximately 30% of cases a clinical cause is not identified. Acute chorioamnionitis is found histologically in a significant percentage of placentas from preterm deliveries
Autor:
Alan D. Bocking, Richard Harding, Carole S. Watson, Susan E. White, Laurence J. Fraher, J. Homan, Rachel Schaefer
Publikováno v:
Reproduction, fertility, and development. 14(1-2)
It was hypothesized that intermittent umbilical cord occlusion (UCO) would inhibit ovine fetal breathing movements (FBM) in association with increased cerebral adenosine levels. To test this hypothesis, on two successive days during late gestation (1