Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Carole Lepine"'
Autor:
Deborah A. Nicoll-Griffith, Pierre Hamel, Carole Lepine, C. C. Chan, Chun Li, C. S. Mcfarlane, Yves Girard, James A. Yergey, Yves Ducharme, Daniel Dube, Christine Brideau, Nathalie Chauret, Daniel Delorme, Thomas R. Jones, Rejean Fortin, Denis Riendeau, M. McAuliffe, Jocelyne Guay, Sylvie Desmarais, Jean-Pierre Falgueyret
Publikováno v:
Journal of Medicinal Chemistry. 39:3951-3970
Naphthalenic lignan lactone 3a (L-702,539), a potent and selective 5-lipoxygenase (5-LO) inhibitor, is extensively metabolized at two different sites: the tetrahydropyran and the lactone rings. Early knowledge of the metabolic pathways triggered and
Autor:
John H. Hutchinson, Carole Lepine, Jean-Pierre Falgueyret, C. Chan, Christine Brideau, C. S. Mcfarlane, Jocelyne Guay, Dwight Macdonald, Thomas R. Jones, Denis Riendeau
Publikováno v:
Journal of Medicinal Chemistry. 37:1153-1164
Leukotriene biosynthesis inhibitors have potential as new therapies for asthma and inflammatory diseases. The recently disclosed thiopyrano[2,3,4-cd]indole class of 5-lipoxygenase (5-LO) inhibitors has been investigated with particular emphasis on th
Publikováno v:
Tetrahedron Letters. 35:1843-1846
Rearrangement of acetylated 5-O- p -toluenesulfonyl-L-arabinose dibenzyl dithioacetal 10 gave benzyl 1,5-dithio-L-arabinopyranoside 6 which upon anomeric bromination followed by glycosidation led to pseudodisaccharide 20 containing a sulfur atom in t
Publikováno v:
ChemInform. 25
Autor:
Deborah A. Nicoll-Griffith, Pierre Hamel, Denis Riendeau, Jocelyne Guay, Christine Brideau, Carole Lepine, Thomas R. Jones, Sylvie Desmarais, Chun Li, Jean-Pierre Falgueyret, M. McAuliffe, C. S. Mcfarlane, Yves Ducharme, Daniel Dube, Daniel Delorme, James A. Yergey, Nathalie Chauret, Rejean Fortin, C. C. Chan, Yves Girard
Publikováno v:
ChemInform. 28
Naphthalenic lignan lactone 3a (L-702,539), a potent and selective 5-lipoxygenase (5-LO) inhibitor, is extensively metabolized at two different sites: the tetrahydropyran and the lactone rings. Early knowledge of the metabolic pathways triggered and
Publikováno v:
The Journal of Organic Chemistry. 56:4494-4498
The transannular cyclopropanation of a keto carbene generated by Rh 2 (OAc) 4 catalysis on a bicyclic dihydropyran nucleus provided a key oxatricyclic ketone intermediate for the synthesis of the [6.6] spirocyclic ring construction. Selective fragmen