Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Carole L. Galligan"'
Autor:
Carole L Galligan, Janet C Siebert, Katherine A Siminovitch, Edward C Keystone, Vivian Bykerk, Omar D Perez, Eleanor N Fish
Publikováno v:
PLoS ONE, Vol 4, Iss 8, p e6703 (2009)
BACKGROUND:The precise mechanisms involved in the initiation and progression of rheumatoid arthritis (RA) are not known. Early stages of RA often have non-specific symptoms, delaying diagnosis and therapy. Additionally, there are currently no establi
Externí odkaz:
https://doaj.org/article/81995df7cd15419cb4d328cda0935399
Autor:
Carole L. Galligan, Eleanor N. Fish
Publikováno v:
Journal of interferoncytokine research : the official journal of the International Society for Interferon and Cytokine Research. 37(10)
Rheumatoid arthritis (RA) is a systemic autoimmune disease affecting multiple joints. It remains unclear which factors in the circulation are associated with the systemic spread of the disease. Fibrocytes are pluripotent mesenchymal stem cells presen
Autor:
Carole L. Galligan, Eleanor N. Fish
Publikováno v:
Journal of Leukocyte Biology. 93:45-50
Review on the role of circulating fibrocytes in augmenting the inflammatory/immune processes, and contributing to tissue remodeling in autoimmune diseases. Autoimmunity is a chronic process resulting in inflammation, tissue damage, and subsequent tis
Autor:
Carole L. Galligan, Eleanor N. Fish
Publikováno v:
Arthritis & Rheumatism. 64:3583-3593
Objective Rheumatoid arthritis (RA) is a systemic autoimmune disease resulting in joint inflammation. Fibroblast-like synoviocytes in affected joints are responsible for pannus formation and cytokine/chemokine production, resulting in leukocyte recru
Publikováno v:
Journal of autoimmunity. 69
Rheumatoid arthritis (RA) is a systemic autoimmune disease. We previously identified a circulating cell population, fibrocytes, which is activated early in disease. As RA is characterized by the formation of autoantibodies and autoreactive T cells, w
Autor:
Beata Majchrzak-Kita, Leesa M. Pennell, Reza Rahbar, Eleanor N. Fish, Ehtesham Baig, Thomas T. Murooka, Carole L. Galligan
Publikováno v:
Multiple Sclerosis Journal. 16:1458-1473
Background: Interferon (IFN)-β is an effective therapy for relapsing-remitting multiple sclerosis, yet its mechanism of action remains ill-defined. Objectives: Our objective was to characterize the role of IFN-β in immune regulation in experimental
Publikováno v:
The Journal of Experimental Medicine
Antiinfluenza type 2 (T2) immunity contributes to both immunopathology and immunoprotection, yet the underlying mechanisms modulating T2 immunity remain ill defined. We describe a novel mouse antigen (Ag)-presenting cell (APC), designated late-activa
Publikováno v:
J Immunol
MCP-1/CCL2 plays a critical role in monocyte recruitment into sites of immune responses and cancer. However, the role of other MCPs remains unclear. In this study, we generated a novel MCP-1-deficient (designated as MCP-1Δ/Δ) mouse model by deletin
Autor:
Carole L. Galligan, Eleanor N. Fish
Publikováno v:
Sex and Gender Differences in Infection and Treatments for Infectious Diseases ISBN: 9783319164373
The distinct differences between males and females in the incidence of infections, the severity of disease, and the likely outcome are a consequence of sex-related differences in immune cell composition and activation following exposure to a pathogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb181ea966a557b80e4b090b616a4d0c
https://doi.org/10.1007/978-3-319-16438-0_1
https://doi.org/10.1007/978-3-319-16438-0_1
Autor:
Raj Deonarain Newman, Eleanor N. Fish, Karen E. Thomas, Carole L. Galligan, Stefanie N. Vogel
Publikováno v:
Journal of Biological Chemistry. 281:31119-31130
Interferon-beta (IFN-beta) has been identified as the signature cytokine induced via the Toll-like receptor (TLR) 4, "MyD88-independent" signaling pathway in macrophages stimulated by Gram-negative bacterial lipopolysaccharide (LPS). In this study, w