Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Carole Kurahara"'
Autor:
Betsy Daugherty, Caroline Bishop, Chen Dong, Yongliang Zhang, Paige Holst, Ning Sun, Fred D. Lott, Yeonseok Chung, Andrew A. Welcher, Carole Kurahara, Hilary T. Chute
Publikováno v:
Proceedings of the National Academy of Sciences. 103:11695-11700
T cell activation and tolerance are regulated by costimulatory molecules. Although PD-1 serves as a crucial negative regulator of T cells, the function of its ligands, PDL1 and PDL2, is still controversial. In this study, we created a PDL2-deficient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18c51556f92c44957f51e1b2781eb91d
https://doi.org/10.1073/pnas.0601347103
https://doi.org/10.1073/pnas.0601347103
Autor:
Manley Huang, Dan Chen, Roanna Ueda, Yifan Mao, Carole Kurahara, Fiona A. Harding, Gerard Platenburg, Namrata Patil
Publikováno v:
European Journal of Immunology. 33:172-182
Linkage studies indicate close associations of certain HLA alleles with autoimmune diseases. To better understand how specific HLA alleles are related to disease pathogenesis, we have generated an HLA DR3/DQ2 transgenic mouse utilizing a 550-kb yeast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac9912aa2a955ae82ea936c606625c91
https://doi.org/10.1002/immu.200390020
https://doi.org/10.1002/immu.200390020
Autor:
Paul J. Kostenuik, Michael S. Ominsky, Ildiko Sarosi, Jin Cao, Yongming Gao, Mauricio Barrero, Carole Kurahara, Betsy Daugherty, Chris Paszty, Kelly S Warmington, Xiaodong Li, Hua Zhu Ke, Sean Morony, Jianhua Gong, W. Scott Simonet, Ning Sun, Frank Asuncion, Diane D'Agostin, Denise Dwyer, Qing-Tian Niu, Marina Stolina, David L. Lacey
Publikováno v:
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 23(6)
Introduction: Sclerosteosis is a rare high bone mass genetic disorder in humans caused by inactivating mutations in SOST, the gene encoding sclerostin. Based on these data, sclerostin has emerged as a key negative regulator of bone mass. We generated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f25594c405cba9c493e97dc5d49e39f
https://pubmed.ncbi.nlm.nih.gov/18269310
https://pubmed.ncbi.nlm.nih.gov/18269310
Autor:
David Salom, Krzysztof Palczewski, Timothy J. R. Harris, O Marcin Golczak, Ning Li, Carole Kurahara, John A. Salon, Li Zhang, Todd Juan, Steven R. Jordan, Beata Jastrzebska, Juan A. Ballesteros
Publikováno v:
Biochemistry. 46(28)
Traditional cell-based systems used to express integral membrane receptors have yet to produce protein samples of sufficient quality for structural study. Herein we report an in vivo method that harnesses the photoreceptor system of the retina to het
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d0b7152f00dc6a5d0a33dea758abed2
https://pubmed.ncbi.nlm.nih.gov/17580959
https://pubmed.ncbi.nlm.nih.gov/17580959
Autor:
William R. Clark, Mehrdad Matloubian, Carole Kurahara, Julie L. Christensen, Roanne Ueda, Manley T. F. Huang, Chau-Ching Liu, John Ding-E Young, Craig M. Walsh, Rafi Ahmed
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 91(23)
Mice lacking the perforin gene were generated by using targeted gene disruption in embryonal stem cells. When infected with lymphocytic choriomeningitis virus (LCMV), perforin-less (-/-) mice showed clear signs of having mounted an immune response ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e16fe38b29f44a3d7c8345c090817dc5
https://pubmed.ncbi.nlm.nih.gov/7526382
https://pubmed.ncbi.nlm.nih.gov/7526382