Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Carole J. Coffee"'
Publikováno v:
Journal of Biological Chemistry. 252:563-573
Gaucher's disease is a lysosomal storage disease caused by a deficiency in the enzyme glucocerebrosidase. A small, heat-stable glycoprotein first obtained from Gaucher spleen (Ho, M. W., and O'Brien, J. S. (1971) Proc. Natl. Acad. Sci. U. S.A. 68, 28
Autor:
Cynthia Solano, Carole J. Coffee
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Protein Structure. 453:67-80
The calcium-binding protein (parvalbumin), isolated from carp (Cyprinus carpio) muscle, has been specifically fragmented into two polypeptides by tryptic hydrolysis at the single arginine residue at position 75. Fragment A contains residues 1 a 75 an
Autor:
Carole J. Coffee, Robert H. Glew
Publikováno v:
Archives of Biochemistry and Biophysics. 229:55-63
Lysosomal glucocerebrosidase of human tissues is reversibly inactivated by extraction with sodium cholate and n-butanol. Enzyme activity can be restored in the glucocerebrosidase assay by the incorporation of small amounts of phosphatidylserine (1 μ
Publikováno v:
Enzyme. 30:223-229
A modification of the zinc-barium precipitation method is described for the measurement of phosphodiesterase activity. This method differs from the previous precipitation method in that it measures the appearance of the 5'-AMP product in the precipit
Publikováno v:
Metabolism. 28:169-182
A troponin C-like phosphodiesterase activator from bovine thyroid has been purified to homogeneity. The overall purification was about 9,800-fold with a yield of 8%. Bovine thyroid activator protein is identical in biologic properties to that isolate
Isolation and characterization of the cyanogen bromide glycopeptide fragments of alpha-1-antitrypsin
Publikováno v:
Journal of Biological Chemistry. 253:6992-6996
Autor:
Yu-Teh Li, Su-Chen Li, Robert E. Lee, Stephen P. Peters, Robert H. Glew, David A. Wenger, Carole J. Coffee
Publikováno v:
Archives of Biochemistry and Biophysics. 183:290-297
Heat-stable glycoprotein activator substances which stimulate the activity of human liver glucocerebroside:β-glucosidase have been purified extensively from the spleens of five patients representing the clinical extremes of Gaucher's disease ranging
Autor:
Carole J. Coffee, W A Kofke
Publikováno v:
Journal of Biological Chemistry. 250:6653-6658
AMP deaminase (AMP aminohydrolase, EC 3.5.4.6) has been purified to apparent homogeneity from rat muscle. The preparation exhibits a single polypeptide band with a molecular weight of 60,000 on polyacrylamide gel electrophoresis in the presence of so
Autor:
Norman C. LeDonne, Carole J. Coffee
Publikováno v:
Journal of Biological Chemistry. 254:4317-4320
The calcium-sensitive phosphodiesterase-stimulating activity sometimes associated with parvalbumin preparations is due to contaminating (less than 0.1%) amounts of carp muscle CDR (calcium-dependent regulator)-like protein. This protein can be resolv
Autor:
Carole J. Coffee, Janice M. Sabatine
Publikováno v:
Archives of Biochemistry and Biophysics. 249:95-105
Two soluble cyclic nucleotide phosphodiesterase activities, designated Peak I ( M r = 216,000) and Peak II ( M r = 230,000), have been isolated from bovine adrenal medulla by DEAE-cellulose chromatography. Peak I has Ca 2+ -independent, cGMP-specific