Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Carole I. Westacott"'
Autor:
Barakat, A.F. a, Elson, C.J. b, Westacott, C.I. b, f1f1Address correspondence to: Carole I. Westacott, PhD, Department of Pathology and Microbiology, School of Medical Sciences, University of Bristol, University Walk, Bristol, BS8 1TD, U.K. Tel: 44 117 9288605; Fax: 44 117 9287896; E-mail:carole.westacott@bristol.ac.uk
Publikováno v:
In Osteoarthritis and Cartilage April 2002 10(4):264-269
Publikováno v:
Osteoarthritis and Cartilage. 10:264-269
Objectives To determine whether cartilage biopsies from specific regions of osteoarthritic knee joints differ in susceptibility to the degradative effects of the amounts of interleukin-1β (IL-1β; 1–10pg/ml) found in osteoarthritic joints. To esta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6307a41ae7aa4c8732990808bda2a62b
https://doi.org/10.1053/joca.2002.0515
https://doi.org/10.1053/joca.2002.0515
Autor:
Christopher J. Elson, Carole I. Westacott, P. Neison, A. B. Millar, L. Wood, M. J. Perry, I. Bisbinas, Amira F. Barakat, L. Armstrong
Publikováno v:
Osteoarthritis and Cartilage. 8(3):213-221
Objective To evaluate the potential for tumor necrosis factor alpha (TNFα)-induced focal loss of cartilage in osteoarthritic (OA) knee joints. Design Fresh cartilage from specified regions of OA joints was immunostained for TNF-receptor (R) bearing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab39a0c51014d7f65687882883af8d0a
Publikováno v:
Osteoarthritis and Cartilage. 6(3):167-176
Objective: To determine whether the up-regulation of chondrocyte tumor necrosis factor receptor (TNF-R) expression in osteoarthritis (OA) is due to molecules released within the OA knee joint. Design: Non-arthritis (NA) human articular chondrocytes w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b059d2d4e3ea87fc95b208bba4e30151
Publikováno v:
Arthritis & Rheumatism. 40:1282-1291
Objective. To determine whether bone cells alter cartilage metabolism. Methods. Bone cell cultures were established using explants obtained from the hip and knee joints of 9 patients with osteoarthritis (OA) and 6 subjects without arthritis (nonarthr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bc047ec46cbcb86f395db7cee8f6a1c
https://doi.org/10.1002/art.1780400713
https://doi.org/10.1002/art.1780400713
Autor:
Carole I. Westacott, Mohammed Sharif
Publikováno v:
Seminars in Arthritis and Rheumatism. 25:254-272
Objective: The integrity of articular cartilage is maintained by the balance between cytokine-driven anabolic and catabolic processes. Unregulated or excess influences of these molecules are thought to play a part in the pathophysiology of many joint
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e05aabd48ee3a9917e27c93d49d553f3
https://doi.org/10.1016/s0049-0172(96)80036-9
https://doi.org/10.1016/s0049-0172(96)80036-9
Publikováno v:
Osteoarthritis and cartilage. 5(6)
Summary Objective Osteoarthritis (OA) is characterized by focal loss of cartilage. Here we show for the first time that tumor necrosis factor (TNF) α can act on cartilage but only at specific sites where chondrocyte TNFα-receptor (R) expression is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf1328f13f1b0de77214b6832ede2323
https://pubmed.ncbi.nlm.nih.gov/9536291
https://pubmed.ncbi.nlm.nih.gov/9536291