Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Carole Ho"'
Autor:
Maurits F. J. M. Vissers, Jules A. A. C. Heuberger, Geert Jan Groeneveld, Jerome Oude Nijhuis, Peter Paul De Deyn, Salah Hadi, Jeffrey Harris, Richard M. Tsai, Andres Cruz‐Herranz, Fen Huang, Vincent Tong, Rebecca Erickson, Yuda Zhu, Kimberly Scearce‐Levie, Jennifer Hsiao‐Nakamoto, Xinyan Tang, Megan Chang, Brian M. Fox, Anthony A. Estrada, Robert J. Pomponio, Miguel Alonso‐Alonso, Moshe Zilberstein, Nazem Atassi, Matthew D. Troyer, Carole Ho
Publikováno v:
Clinical and Translational Science, Vol 15, Iss 8, Pp 2010-2023 (2022)
Abstract RIPK1 is a master regulator of inflammatory signaling and cell death and increased RIPK1 activity is observed in human diseases, including Alzheimer’s disease (AD) and amyotrophic lateral sclerosis (ALS). RIPK1 inhibition has been shown to
Externí odkaz:
https://doaj.org/article/b9ff23b0f0ad4f13a0f534eb7f32e626
Autor:
Fen Huang, Yuda Zhu, Jennifer Hsiao‐Nakamoto, Xinyan Tang, Jason C. Dugas, Miriam Moscovitch‐Lopatin, Jonathan D. Glass, Robert H. Brown Jr, Shafeeq S. Ladha, David Lacomis, Jeffrey M. Harris, Kimberly Scearce‐Levie, Carole Ho, Robert Bowser, James D. Berry
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 7, Iss 7, Pp 1103-1116 (2020)
Abstract Objective To investigate neurodegenerative and inflammatory biomarkers in people with amyotrophic lateral sclerosis (PALS), evaluate their predictive value for ALS progression rates, and assess their utility as pharmacodynamic biomarkers for
Externí odkaz:
https://doaj.org/article/11d05d5c58d74cc2b606aa11605a30ba
Autor:
Stephen Salloway, Lee A. Honigberg, William Cho, Michael Ward, Michel Friesenhahn, Flavia Brunstein, Angelica Quartino, David Clayton, Deborah Mortensen, Tobias Bittner, Carole Ho, Christina Rabe, Stephen P. Schauer, Kristin R. Wildsmith, Reina N. Fuji, Shehnaaz Suliman, Eric M. Reiman, Kewei Chen, Robert Paul
Publikováno v:
Alzheimer’s Research & Therapy, Vol 10, Iss 1, Pp 1-13 (2018)
Abstract Background We investigated the effect of crenezumab, a humanized anti-amyloid-beta (Aβ) immunoglobulin (Ig)G4 monoclonal antibody, on biomarkers of amyloid pathology, neurodegeneration, and disease progression in patients with mild-to-moder
Externí odkaz:
https://doaj.org/article/a311ee7ca9264e6696bffa8520f93ab9
Autor:
Danna Jennings, Sarah Huntwork‐Rodriguez, Maurits F.J.M. Vissers, Vinay M. Daryani, Dolores Diaz, Marisa S. Goo, John J. Chen, Romeo Maciuca, Kyle Fraser, Omar S. Mabrouk, Jeroen van de Wetering de Rooij, Jules A.A.C. Heuberger, Geert Jan Groeneveld, Marie T. Borin, Andrés Cruz‐Herranz, Danielle Graham, Kimberly Scearce‐Levie, Javier De Vicente, Anastasia G. Henry, Peter Chin, Carole Ho, Matthew D. Troyer
Publikováno v:
Movement Disorders. 38:386-398
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d841a1a342eb88953aff7521961de4ba
https://doi.org/10.1002/mds.29297
https://doi.org/10.1002/mds.29297
Autor:
Maurits F. J. M. Vissers, Jules A. A. C. Heuberger, Geert Jan Groeneveld, Jerome Oude Nijhuis, Peter Paul De Deyn, Salah Hadi, Jeffrey Harris, Richard M. Tsai, Andres Cruz‐Herranz, Fen Huang, Vincent Tong, Rebecca Erickson, Yuda Zhu, Kimberly Scearce‐Levie, Jennifer Hsiao‐Nakamoto, Xinyan Tang, Megan Chang, Brian M. Fox, Anthony A. Estrada, Robert J. Pomponio, Miguel Alonso‐Alonso, Moshe Zilberstein, Nazem Atassi, Matthew D. Troyer, Carole Ho
Publikováno v:
Clinical and Translational Science. 15:2010-2023
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95cdda02d84a3c460709facb87673a93
https://doi.org/10.1111/cts.13317
https://doi.org/10.1111/cts.13317
Autor:
Linus Sun, Richard Tsai, Ernie Yulyaningsih, Melania Fanok, Maurits Vissers, Jules Heuberger, Brittany Flores, Fen Huang, Lesley Kane, Isaac Cohen, Shyeilla Dhuria, Meng Fang, Anthony Estrada, Maksim Osipov, Brent Willman-Yoswa, Romeo Maciuca, Sarah Dobbins, Ronnie Chau, Timothy Earr, Hoang Nguyen, Isabel Lopez, Kimberly Scearce-Levie, Tommy Bunte, Leonard Van den Berg, Carole Ho, Geert-Jan Groeneveld, Matthew Troyer
Publikováno v:
Tuesday, April 25.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83680c70d0bf6b1ff48df110caa9d8ee
https://doi.org/10.1212/wnl.0000000000203354
https://doi.org/10.1212/wnl.0000000000203354
Autor:
Danna Jennings, Sarah Huntwork-Rodriguez, Anastasia G. Henry, Jennifer C. Sasaki, René Meisner, Dolores Diaz, Hilda Solanoy, Xiang Wang, Elvira Negrou, Vitaliy V. Bondar, Rajarshi Ghosh, Michael T. Maloney, Nicholas E. Propson, Yuda Zhu, Romeo D. Maciuca, Laura Harris, Angela Kay, Peter LeWitt, T. Alex King, Drew Kern, Aaron Ellenbogen, Ira Goodman, Andrew Siderowf, Jason Aldred, Omid Omidvar, Shababa T. Masoud, Sonnet S. Davis, Annie Arguello, Anthony A. Estrada, Javier de Vicente, Zachary K. Sweeney, Giuseppe Astarita, Marie T. Borin, Bradley K. Wong, Harvey Wong, Hoang Nguyen, Kimberly Scearce-Levie, Carole Ho, Matthew D. Troyer
Publikováno v:
Science Translational Medicine. 14
Mutations in leucine-rich repeat kinase 2 ( LRRK2 ) are the most common genetic risk factors for Parkinson’s disease (PD). Increased LRRK2 kinase activity is thought to impair lysosomal function and may contribute to the pathogenesis of PD. Thus, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12d447b718b56152fa35afc4ad299bcf
https://doi.org/10.1126/scitranslmed.abj2658
https://doi.org/10.1126/scitranslmed.abj2658
Autor:
Jennifer Hsiao-Nakamoto, James D. Berry, Yuda Zhu, Robert H. Brown, Xinyan Tang, Kimberly Scearce-Levie, Jeffrey M. Harris, Fen Huang, Robert Bowser, David Lacomis, Shafeeq Ladha, Jonathan D. Glass, Carole Ho, Miriam Moscovitch-Lopatin, Jason C. Dugas
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 7, Iss 7, Pp 1103-1116 (2020)
Annals of Clinical and Translational Neurology
Annals of Clinical and Translational Neurology
Objective To investigate neurodegenerative and inflammatory biomarkers in people with amyotrophic lateral sclerosis (PALS), evaluate their predictive value for ALS progression rates, and assess their utility as pharmacodynamic biomarkers for monitori
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32a81ca9ea27254e5a85039dad453763
https://doaj.org/article/11d05d5c58d74cc2b606aa11605a30ba
https://doaj.org/article/11d05d5c58d74cc2b606aa11605a30ba
Autor:
Joseph Muenzer, Paul Harmatz, Barbara K. Burton, Deepa Rajan, Simon A. Jones, Steven D. Chessler, Natalie Engmann, Adam Scheller, Charlene Chen, Rupa Caprihan, Akhil Bhalla, Tony Hung, Jason Nachtigall, Imanol Zubizarreta, Angela Kay, Simona Costanzo, Jeffrey M. Harris, Yuda Zhu, Peter Chin, Matthew D. Troyer, Carole Ho, Anna I. Bakardjiev
Publikováno v:
Molecular Genetics and Metabolism. 138:107231
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97c81e9979efef396314d9673a17e816
https://doi.org/10.1016/j.ymgme.2022.107231
https://doi.org/10.1016/j.ymgme.2022.107231
Autor:
Jose Alcantara Rodriguez, Jeff Harris, Peter Cygon, Yuda Zhu, Natalie Engmann, Simona Costanzo, Fabian Model, Wei Dong, Carole Ho, Peter Chin
Publikováno v:
Molecular Genetics and Metabolism. 138:106996
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d54a60f55d41c4a1ca0668e504cafd1
https://doi.org/10.1016/j.ymgme.2022.106996
https://doi.org/10.1016/j.ymgme.2022.106996