Voluntary exercise in mice triggers an anti-osteogenic and pro-tenogenic response in the ankle joint without affecting long bones

Autor: Anne Briolay, François Duboeuf, Séverine Delplace, Leyre Brizuela, Olivier Peyruchaud, David Magne, Carole Bougault

Publikováno v: Bone Reports, Vol 23, Iss , Pp 101810- (2024)

Biomechanical stimulation is proposed to occupy a central place in joint homeostasis, but the precise contribution of exercise remains elusive. We aimed to characterize in vivo the impact of mechanical stimulation on the cell-controlled regulation of

Externí odkaz: https://doaj.org/article/4a410d3b997b4d3faa7d63d7c00eb3e2

Dynamic compression of chondrocyte-agarose constructs reveals new candidate mechanosensitive genes.

Autor: Carole Bougault, Elisabeth Aubert-Foucher, Anne Paumier, Emeline Perrier-Groult, Ludovic Huot, David Hot, Martine Duterque-Coquillaud, Frédéric Mallein-Gerin

Publikováno v: PLoS ONE, Vol 7, Iss 5, p e36964 (2012)

Articular cartilage is physiologically exposed to repeated loads. The mechanical properties of cartilage are due to its extracellular matrix, and homeostasis is maintained by the sole cell type found in cartilage, the chondrocyte. Although mechanical

Externí odkaz: https://doaj.org/article/bdd9f7e4f3e4424ab3728592b59b5ea2

Cytokine‐Induced and Stretch‐Induced Sphingosine 1‐Phosphate Production by Enthesis Cells Could Favor Abnormal Ossification in Spondyloarthritis

Autor: David Magne, Anne Briolay, Carole Bougault, Benoit Le Goff, Leyre Brizuela, Frédéric Blanchard, Alaeddine El Jamal, Saida Mebarek

Publikováno v: Journal of Bone and Mineral Research. 34:2264-2276

Spondyloarthritis (SpA) is a common rheumatic disease characterized by enthesis inflammation (enthesitis) and ectopic ossification (enthesophytes). The current pathogenesis model suggests that inflammation and mechanical stress are both strongly invo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2735656fa57700451b4e9985903f8fd5
https://doi.org/10.1002/jbmr.3844

TNAP stimulates vascular smooth muscle cell trans-differentiation into chondrocytes through calcium deposition and BMP-2 activation: Possible implication in atherosclerotic plaque stability

Autor: Alain Guignandon, Bassam Badran, Eva Hamade, Juan Ignacio Díaz-Hernández, Anne Briolay, David Magne, Laurence Bessueille, Carole Bougault, René Buchet, Monika Roszkowska, Miguel Díaz-Hernández, Slawomir Pikula, Maya Fakhry

Publikováno v: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1863:643-653

Atherosclerotic plaque calcification varies from early, diffuse microcalcifications to a bone-like tissue formed by endochondral ossification. Recently, a paradigm has emerged suggesting that if the bone metaplasia stabilizes the plaques, microcalcif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1682fa6b2412d63b5bfa23cba6de336
https://doi.org/10.1016/j.bbadis.2016.12.003

Pyrocarbon versus cobalt-chromium in the context of spherical interposition implants: an in vitro study on cultured chondrocytes

Autor: Yves Berthier, Saida Mebarek, G. Ouenzerfi, Leyre Brizuela, A. Hannoun, M. Hassler, Carole Bougault, Ana-Maria Trunfio-Sfarghiu

Publikováno v: eCells and Materials Journal
eCells and Materials Journal, AO Research Institute Davos, 2019, 37, pp.1-15. ⟨10.22203/eCM.v037a01⟩
European Cells & Materials, Vol 37, Pp 1-15 (2019)

In the context of shoulder surgical replacement, a new generation of spherical interposition implants has been developed, with the implant being a mobile spacer rubbing against the glenoid cartilage and humeral bone cavity. The aim of the present stu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2f971ec2262368c2a8cd35c646a4374
https://hal.archives-ouvertes.fr/hal-02133470