Zobrazeno 1 - 10
of 127
pro vyhledávání: '"Carole B Miller"'
Publikováno v:
Advances in Hematology, Vol 2022 (2022)
Background. Convalescent plasma obtained from individuals who have recovered from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) contains neutralizing antibodies to the virus and has been frequently used as a treatment in hospitalized p
Externí odkaz:
https://doaj.org/article/c793645c2ed241c5b296b6b6be560895
Autor:
Srdan Verstovsek, Ruben A. Mesa, Jason Gotlib, Vikas Gupta, John F. DiPersio, John V. Catalano, Michael W. N. Deininger, Carole B. Miller, Richard T. Silver, Moshe Talpaz, Elliott F. Winton, Jimmie H. Harvey, Murat O. Arcasoy, Elizabeth O. Hexner, Roger M. Lyons, Ronald Paquette, Azra Raza, Mark Jones, Deanna Kornacki, Kang Sun, Hagop Kantarjian, for the COMFORT-I investigators
Publikováno v:
Journal of Hematology & Oncology, Vol 10, Iss 1, Pp 1-14 (2017)
Abstract Background The randomized, double-blind, placebo-controlled, phase 3 COMFORT-I trial evaluated the JAK1/JAK2 inhibitor ruxolitinib in patients with intermediate-2/high-risk myelofibrosis. The primary and planned 3-year analyses of COMFORT-I
Externí odkaz:
https://doaj.org/article/7414efd9cbe24affac81f3167f71f9d0
Autor:
Vikas Gupta, Abdulraheem Yacoub, Srdan Verstovsek, Ruben Mesa, Claire Harrison, Alessandro M. Vannucchi, Jean-Jacques Kiladjian, H. Joachim Deeg, Salman Fazal, Lynda Foltz, Ryan J. Mattison, Carole B. Miller, Vinod Parameswaran, Patricia Martin-Regueira, Christopher Hernandez, Jia Wang, Moshe Talpaz
Publikováno v:
Blood. 140:3935-3937
Autor:
Hyam I. Levitsky, Kristen Hege, Richard Jones, Guang Haun Tu, Thomas C. Harding, Barbara Biedrzycki, Christina Chia, Lu Qin, Hua-Ling Tsai, Elizabeth Garrett-Mayer, Carole B. Miller, Kathleen Murphy, Christopher Gocke, Jeanne Kowalski, Yvette L. Kasamon, B. Douglas Smith
Purpose: Chronic myeloid leukemia (CML) can be responsive to T-cell–mediated immunity. K562/granulocyte macrophage-colony stimulating factor (GM-CSF) is a GM-CSF producing vaccine derived from a CML cell line that expresses several CML-associated a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::259cce9075d95e9c8508b5e08dc816d5
https://doi.org/10.1158/1078-0432.c.6518467
https://doi.org/10.1158/1078-0432.c.6518467
Autor:
Hyam I. Levitsky, Kristen Hege, Richard Jones, Guang Haun Tu, Thomas C. Harding, Barbara Biedrzycki, Christina Chia, Lu Qin, Hua-Ling Tsai, Elizabeth Garrett-Mayer, Carole B. Miller, Kathleen Murphy, Christopher Gocke, Jeanne Kowalski, Yvette L. Kasamon, B. Douglas Smith
Supplementary Data from K562/GM-CSF Immunotherapy Reduces Tumor Burden in Chronic Myeloid Leukemia Patients with Residual Disease on Imatinib Mesylate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53ae04ff2945ed73b9f14b49f95b4e63
https://doi.org/10.1158/1078-0432.22441387.v1
https://doi.org/10.1158/1078-0432.22441387.v1
Autor:
Srdan Verstovsek, Alessandro M. Vannucchi, Martin Griesshammer, Tamas Masszi, Simon Durrant, Francesco Passamonti, Claire N. Harrison, Fabrizio Pane, Pierre Zachee, Keita Kirito, Carlos Besses, Masayuki Hino, Beatriz Moiraghi, Carole B. Miller, Mario Cazzola, Vittorio Rosti, Igor Blau, Ruben Mesa, Mark M. Jones, Huiling Zhen, Jingjin Li, Nathalie Francillard, Dany Habr, Jean-Jacques Kiladjian
Publikováno v:
Haematologica, Vol 101, Iss 7 (2016)
RESPONSE is an open-label phase 3 study evaluating the Janus kinase 1/Janus kinase 2 inhibitor ruxolitinib versus best available therapy for efficacy/safety in hydroxyurea-resistant or intolerant patients with polycythemia vera. This preplanned analy
Externí odkaz:
https://doaj.org/article/418f46ca455548afb6402a31a5392284
Autor:
Elisa Rumi, Tamás Masszi, Ruben A. Mesa, Jean-Jacques Kiladjian, Francesco Passamonti, Tuochuan Dong, Nathalie Francillard, Vittorio Rosti, Srdan Verstovsek, Beatriz Moiraghi, Carlos Besses, Simon Durrant, Masayuki Hino, Pierre Zachee, Fabrizio Pane, Claire N. Harrison, Martin Griesshammer, Alessandro M. Vannucchi, Monika Wroclawska, Keita Kirito, Carole B. Miller, Igor Wolfgang Blau
Publikováno v:
Lancet Haematol
Summary Background Polycythaemia vera is a myeloproliferative neoplasm characterised by excessive proliferation of erythroid, myeloid, and megakaryocytic components in the bone marrow due to mutations in the Janus kinase 2 (JAK2) gene. Ruxolitinib, a
Autor:
Srdan Verstovsek, Ruben A. Mesa, Jason Gotlib, Richard S. Levy, Vikas Gupta, John F. DiPersio, John V. Catalano, Michael W.N. Deininger, Carole B. Miller, Richard T. Silver, Moshe Talpaz, Elliott F. Winton, Jimmie H. Harvey, Murat O. Arcasoy, Elizabeth O. Hexner, Roger M. Lyons, Azra Raza, Kris Vaddi, William Sun, Wei Peng, Victor Sandor, Hagop Kantarjian
Publikováno v:
Haematologica, Vol 100, Iss 4 (2015)
In the phase III COMFORT-I study, the Janus kinase 1 (JAK1)/JAK2 inhibitor ruxolitinib provided significant improvements in splenomegaly, key symptoms, and quality-of-life measures and was associated with an overall survival benefit relative to place
Externí odkaz:
https://doaj.org/article/7b14e5f72f2a48e1a0c3dbba240ffc5c
Autor:
Srdan Verstovsek, Ruben A. Mesa, Jason Gotlib, Richard S. Levy, Vikas Gupta, John F. DiPersio, John V. Catalano, Michael W.N. Deininger, Carole B. Miller, Richard T. Silver, Moshe Talpaz, Elliott F. Winton, Jimmie H. Harvey, Murat O. Arcasoy, Elizabeth O. Hexner, Roger M. Lyons, Ronald Paquette, Azra Raza, Kris Vaddi, Susan Erickson-Viitanen, William Sun, Victor Sandor, Hagop M. Kantarjian
Publikováno v:
Haematologica, Vol 98, Iss 12 (2013)
COMFORT-I is a randomized, double-blind, placebo-controlled trial of the Janus kinase 1/Janus kinase 2 inhibitor ruxolitinib in 309 patients with intermediate-2 or high-risk myelofibrosis. This analysis of COMFORT-I describes the long-term efficacy a
Externí odkaz:
https://doaj.org/article/eb6fdd88d68b49a881699bb335455fab
Autor:
Adam R. Craig, Valentín García-Gutiérrez, Carole B. Miller, Adam J. Mead, Alessandro M. Vannucchi, Stephen T. Oh, Diane R. Mould, Miklos Egyed, John Mascarenhas, Raajit K. Rampal, Michael R. Savona, Sri Devineni, Kaori Ito, Jean-Jacques Kiladjian, Aaron T. Gerds, Claire N. Harrison, Jeanne Palmer, Karisse Roman-Torres, Shanthakumar Tyavanagimatt, Moshe Talpaz, Jennifer O'Sullivan, Prithviraj Bose, Sarah A. Buckley, Bart L. Scott, Abdulraheem Yacoub, Jennifer A. Smith
Publikováno v:
Blood Adv
PAC203 is a randomized dose-finding study of pacritinib, an oral JAK2/IRAK1 inhibitor, in patients with advanced myelofibrosis who are intolerant of or resistant to ruxolitinib. Patients were randomized 1:1:1 to pacritinib 100 mg once per day, 100 mg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::197465cd8da7df3d035d8681e7a61938
https://europepmc.org/articles/PMC7686901/
https://europepmc.org/articles/PMC7686901/