Deep sequencing of biofilm microbiomes on dental composite materials

Autor: Georg Conrads, Laura Katharina Wendt, Franziska Hetrodt, Zhi-Luo Deng, Dietmar Pieper, Mohamed M. H. Abdelbary, Andree Barg, Irene Wagner-Döbler, Christian Apel

Publikováno v: Journal of Oral Microbiology, Vol 11, Iss 1 (2019)

Background: The microbiome on dental composites has not been studied in detail before. It has not been conclusively clarified whether restorative materials influence the oral microbiome. Methods: We used Illumina Miseq next-generation sequencing of t

Externí odkaz: https://doaj.org/article/aea22e4e1e2d40f488d26a2c7f823c99

The Biofilm Inhibitor Carolacton Enters Gram-Negative Cells: Studies Using a TolC-Deficient Strain of Escherichia coli

Autor: Jannik Donner, Michael Reck, Boyke Bunk, Michael Jarek, Constantin Benjamin App, Jan P. Meier-Kolthoff, Jörg Overmann, Rolf Müller, Andreas Kirschning, Irene Wagner-Döbler

Publikováno v: mSphere, Vol 2, Iss 5 (2017)

ABSTRACT The myxobacterial secondary metabolite carolacton inhibits growth of Streptococcus pneumoniae and kills biofilm cells of the caries- and endocarditis-associated pathogen Streptococcus mutans at nanomolar concentrations. Here, we studied the

Externí odkaz: https://doaj.org/article/11b8e6d6ef754cf5a0d7a8bd838a3564

Collaboration in Natural Product Total Synthesis: Carolacton – A Decade of Discovery

Autor: Amy E. Solinski, William M. Wuest

Publikováno v: Synlett. 32:241-248

Carolacton, a macrocyclic natural product with impressive anti-biofilm biological activity, has been a focus in multiple research groups for the past decade. Chemists and biologists, alike, have been interested in uncovering the mechanism of action a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::894c4944a946e5ee2dc065df10df3ba8
https://doi.org/10.1055/s-0040-1707244

Deep sequencing of biofilm microbiomes on dental composite materials

Autor: Christian Apel, Zhi-Luo Deng, Irene Wagner-Döbler, Dietmar H. Pieper, Georg Conrads, Andree Barg, Laura Katharina Wendt, Mohamed M. H. Abdelbary, Franziska Hetrodt

Publikováno v: Journal of Oral Microbiology, Vol 11, Iss 1 (2019)
Journal of Oral Microbiology
Journal of oral microbiology 11(1), 1617013 (2019). doi:10.1080/20002297.2019.1617013
Journal of oral microbiology

Background: The microbiome on dental composites has not been studied in detail before. It has not been conclusively clarified whether restorative materials influence the oral microbiome. Methods: We used Illumina Miseq next-generation sequencing of t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ba1f7c26236051e493c599d59b92d20
https://doaj.org/article/aea22e4e1e2d40f488d26a2c7f823c99

Synthese und Konformationsanalysen und biologische Bewertung von neuen desmethylierten Carolacton-Derivaten

Autor: Meyer, Janina

1998 wurde Carolacton, ein Sekundärmetabolit des Myxobakteriums Sorangium cellulosum (So ce960), am Helmholtz Zentrum für Infektionsforschung in Braunschweig entdeckt und isoliert. Carolacton zeichnet sich durch seine einzigartige Fähigkeit aus, B

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d05b5d682733867cf300211fe4290a8
https://www.repo.uni-hannover.de/handle/123456789/10402