Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Carola Wild"'
Autor:
Georg Breier, Karl H. Plate, Regina Heidenreich, Carola Wild, Marcia Machein, Matthias Clauss, Andreas Hilbig, Anke Nicolaus
Publikováno v:
International Journal of Cancer. 111:348-357
Vascular endothelial growth factor (VEGF) and the highaffinity VEGF receptor Flk-1/KDR (VEGFR-2) are key regulators of tumor angiogenesis. Strategies to block VEGF/ VEGFR-2 signaling were successfully used to inhibit experimental tumor growth and ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3e301995ba4567126b17ac2044a9dfe
https://doi.org/10.1002/ijc.20260
https://doi.org/10.1002/ijc.20260
Autor:
Georg Breier, Sabine Blum, Ernst Reichmann, Marcel Groot, Janos Peli, Carola Wild, Werner Risau
Publikováno v:
International Journal of Cancer. 97:142-148
The formation of new microvasculature by capillary sprouting, or angiogenesis, is a prerequisite for solid tumor growth. The genetic alterations required to activate the angiogenic program in tumor angiogenesis are still only vaguely known, but domin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc3d4cd3f2eca8968e0c2f85709e366a
https://doi.org/10.1002/ijc.1599
https://doi.org/10.1002/ijc.1599
Publikováno v:
The EMBO Journal. 15:1443-1450
In previous work on DNA-(cytosine-C5)-methyltransferases (C5-MTases), domains had been identified which are responsible for the sequence specificity of the different enzymes (target-recognizing domains, TRDs). Here we have analyzed the DNA methylatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07e5178e8b201e688d018e70ed5fbc8e
https://doi.org/10.1002/j.1460-2075.1996.tb00486.x
https://doi.org/10.1002/j.1460-2075.1996.tb00486.x
Publikováno v:
The EMBO Journal. 14:2661-2669
Restriction of DNA by the Escherichia coli K-12 McrBC restriction endonuclease, which consists of the two subunits McrB and McrC, depends on the presence of modified cytosine residues in a special constellation. From previous work by others it was kn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49c624be1602268af492ffe561eb875c
https://doi.org/10.1002/j.1460-2075.1995.tb07264.x
https://doi.org/10.1002/j.1460-2075.1995.tb07264.x
Publikováno v:
Journal of molecular biology. 257(5)
A new multispecific cytosine-C5-DNA-methyltransferase (C5-MTase), M.BssHII, was identified in Bacillus stearothermophilus H3. The M.BssHII gene was cloned and sequenced. The amino acid sequence deduced shows the characteristic building plan of a C5-M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81320e8be5ad8f21c7fce8b3da43f0f0
https://pubmed.ncbi.nlm.nih.gov/8632477
https://pubmed.ncbi.nlm.nih.gov/8632477
Publikováno v:
Gene. 157(1-2)
A MTase with a chimeric TRD with the N-terminal half derived from a TRD recognizing GCNGC, the C-terminal half from one with CCWGG recognition, was constructed. Its target specificity is reported.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8118651057afb4c3b2ac3dddfcf1c661
https://pubmed.ncbi.nlm.nih.gov/7607474
https://pubmed.ncbi.nlm.nih.gov/7607474
Publikováno v:
Gene. 114(1)
We have carried out an analysis of the Escherichia coli K-12 mcrBC locus in order to (1) elucidate its genetic organization, (2) to identify the proteins encoded by this region, and (3) to characterize their involvement in the restriction of DNA cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30164c15376d6b1d560b53ca4f5749d1
https://pubmed.ncbi.nlm.nih.gov/1316864
https://pubmed.ncbi.nlm.nih.gov/1316864
Publikováno v:
Gene. 157:103-104
M·BssHII is a new multispecific C5-DNA-methyltransferase recognizing five different targets. As the enzyme has been isolated from a thermophilic Bacillus, the protein should show enhanced intrinsic thermostability and therefore be a promising candid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eedd219c5a73ec9ab318d4049eb214c
https://doi.org/10.1016/0378-1119(95)00723-j
https://doi.org/10.1016/0378-1119(95)00723-j