Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Carola W. Meyer"'
Autor:
Georgia Balsevich, Alexander S. Häusl, Carola W. Meyer, Stoyo Karamihalev, Xixi Feng, Max L. Pöhlmann, Carine Dournes, Andres Uribe-Marino, Sara Santarelli, Christiana Labermaier, Kathrin Hafner, Tianqi Mao, Michaela Breitsamer, Marily Theodoropoulou, Christian Namendorf, Manfred Uhr, Marcelo Paez-Pereda, Gerhard Winter, Felix Hausch, Alon Chen, Matthias H. Tschöp, Theo Rein, Nils C. Gassen, Mathias V. Schmidt
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Stress is recognized as risk factor for the development of type 2 diabetes. Here Balsevich et al. show that the stress responsive co-chaperone FKBP5 regulates glucose metabolism in mice by modulating AS160 phosphorylation, glucose transporter express
Externí odkaz:
https://doaj.org/article/76e5768290f04b6780cef2511b5d398b
Autor:
Dhiraj G. Kabra, Katrin Pfuhlmann, Cristina García-Cáceres, Sonja C. Schriever, Veronica Casquero García, Adam Fiseha Kebede, Esther Fuente-Martin, Chitrang Trivedi, Kristy Heppner, N. Henriette Uhlenhaut, Beata Legutko, Uma D. Kabra, Yuanqing Gao, Chun-Xia Yi, Carmelo Quarta, Christoffer Clemmensen, Brian Finan, Timo D. Müller, Carola W. Meyer, Marcelo Paez-Pereda, Kerstin Stemmer, Stephen C. Woods, Diego Perez-Tilve, Robert Schneider, Eric N. Olson, Matthias H. Tschöp, Paul T. Pfluger
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Histone deacetylases (HDACs) regulate energy metabolism in peripheral tissues, but whether HDACs expressed in the brain influence systemic metabolism is unknown. Here the authors show that hypothalamic HDAC5 expression is affected by the diet and HDA
Externí odkaz:
https://doaj.org/article/05d180e6a43443a4a0aaf1a16b919fe2
Autor:
Susanne Keipert, Maria Kutschke, Daniel Lamp, Laura Brachthäuser, Frauke Neff, Carola W. Meyer, Rebecca Oelkrug, Alexei Kharitonenkov, Martin Jastroch
Publikováno v:
Molecular Metabolism, Vol 4, Iss 7, Pp 537-542 (2015)
Objective: Circulating fibroblast growth factor 21 (FGF21) is an important auto- and endocrine player with beneficial metabolic effects on obesity and diabetes. In humans, thermogenic brown adipose tissue (BAT) was recently suggested as a source of F
Externí odkaz:
https://doaj.org/article/566035c47333469d96352c38e3212bbc
Publikováno v:
Frontiers in Physiology, Vol 8 (2017)
Endothermic organisms rely on tightly balanced energy budgets to maintain a regulated body temperature and body mass. Metabolic phenotyping of mice, therefore, often includes the recording of body temperature. Thermometry in mice is conducted at vari
Externí odkaz:
https://doaj.org/article/79440aac0c2a4117a79793e3205713f9
Autor:
Christoffer Clemmensen, Brian Finan, Katrin Fischer, Robby Zachariah Tom, Beata Legutko, Laura Sehrer, Daniela Heine, Niklas Grassl, Carola W Meyer, Bart Henderson, Susanna M Hofmann, Matthias H Tschöp, Lex HT Van der Ploeg, Timo D Müller
Publikováno v:
EMBO Molecular Medicine, Vol 7, Iss 3, Pp 288-298 (2015)
Abstract We assessed the efficacy of simultaneous agonism at the glucagon‐like peptide‐1 receptor (GLP‐1R) and the melanocortin‐4 receptor (MC4R) for the treatment of obesity and diabetes in rodents. Diet‐induced obese (DIO) mice were chron
Externí odkaz:
https://doaj.org/article/c1558d4a607f4a25a4ebf5a0ff08660d
Autor:
Martin Irmler, Carola W. Meyer, I P Fischer, M. H. Tschöp, M. Hrabě de Angelis, Frauke Neff, Johannes Beckers, Siegfried Ussar, Stephan Sachs, Susanna M. Hofmann
Publikováno v:
Int. J. Obes. 42, 507-517 (2018)
International Journal of Obesity (2005)
International Journal of Obesity (2005)
Background/Objectives: Dieting is a popular yet often ineffective way to lower body weight, as the majority of people regain most of their pre-dieting weights in a relatively short time. The underlying molecular mechanisms driving weight regain and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::600cea87d8d1c631519a76ee74e6cd03
https://doi.org/10.1038/ijo.2017.224
https://doi.org/10.1038/ijo.2017.224
Publikováno v:
Der Chirurg. 87:964-970
Wartezeiten werden von Patienten negativ empfunden und haben so erheblichen Einfluss auf die Patientenzufriedenheit. Das Ziel des hier vorliegenden Forschungsvorhabens war die Erhebung der Wartezeiten bis zum ersten Arztkontakt und damit verbunden di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4fefeba0c7cd6c2097c7345b5d2d32bb
https://doi.org/10.1007/s00104-016-0243-9
https://doi.org/10.1007/s00104-016-0243-9
Publikováno v:
Current Protocols in Mouse Biology
Current comprehensive mouse metabolic phenotyping involves studying energy balance in cohorts of mice via indirect calorimetry, which determines heat release from changes in respiratory air composition. Here, we describe the measurement of daily ener
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85ea137f881401a6985c418962df6b15
https://doi.org/10.1002/9780470942390.mo140216
https://doi.org/10.1002/9780470942390.mo140216
Autor:
Xixi Feng, Felix Hausch, Marily Theodoropoulou, Christiana Labermaier, Marcelo Paez-Pereda, Kathrin Hafner, Matthias H. Tschöp, Andrés Uribe-Mariño, Nils C. Gassen, Carine Dournes, Michaela Breitsamer, Christian Namendorf, Tianqi Mao, Carola W. Meyer, Stoyo Karamihalev, Theo Rein, Gerhard Winter, Sara Santarelli, Manfred Uhr, Max L. Pöhlmann, Alexander S. Häusl, Alon Chen, Georgia Balsevich, Mathias V. Schmidt
Publikováno v:
Nature Communications
NATURE COMMUNICATIONS
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Nat. Commun. 8:1725 (2017)
NATURE COMMUNICATIONS
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Nat. Commun. 8:1725 (2017)
The co-chaperone FKBP5 is a stress-responsive protein-regulating stress reactivity, and its genetic variants are associated with T2D related traits and other stress-related disorders. Here we show that FKBP51 plays a role in energy and glucose homeos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d27d6ef089055faba61ed6891a7f1fc5
http://europepmc.org/articles/PMC5700978
http://europepmc.org/articles/PMC5700978
Publikováno v:
Naturwissenschaften. 101:1003-1006
The grey short-tailed opossum, Monodelphis domestica, has been an established research animal for more than five decades, but relatively, little is known about its thermophysiology. Here we studied core body temperature (T b) and metabolic rate (MR)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f15c6eaef1bfbc120c96f6f807c555b3
https://doi.org/10.1007/s00114-014-1226-7
https://doi.org/10.1007/s00114-014-1226-7