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of 43
pro vyhledávání: '"Carola U, Niesler"'
Publikováno v:
Physiological Reports, Vol 9, Iss 2, Pp n/a-n/a (2021)
Abstract Skeletal muscle regeneration is a complex process influenced by non‐myogenic macrophages and fibroblasts, which acquire different phenotypes in response to changes in the injury milieu or changes in experimental conditions. In vitro, serum
Externí odkaz:
https://doaj.org/article/fc8e0620eeb140179ee7801c08a48629
Publikováno v:
Biochimie. 196:131-142
A wound is considered hard-to-heal when, despite the appropriate clinical analysis and intervention, the wound area reduces by less than a third at four weeks and complete healing fails to occur within 12 weeks. The most prevalent hard-to-heal wounds
Autor:
Carola U. Niesler, Mari van de Vyver
Publikováno v:
Biochimie. 196:121-122
Publikováno v:
Biochimie. 196
Skeletal muscle injury activates satellite cells to proliferate as myoblasts and migrate, differentiate and fuse with existing fibres at the site of injury. Nitric oxide (NO), a free radical produced by NO synthase, is elevated and supports healing a
Publikováno v:
Physiological Reports
Physiological Reports, Vol 9, Iss 2, Pp n/a-n/a (2021)
Physiological Reports, Vol 9, Iss 2, Pp n/a-n/a (2021)
Skeletal muscle regeneration is a complex process influenced by non‐myogenic macrophages and fibroblasts, which acquire different phenotypes in response to changes in the injury milieu or changes in experimental conditions. In vitro, serum stimulat
Autor:
Carola U. Niesler, C. Venter
Publikováno v:
Experimental Cell Research. 370:542-550
Successful skeletal muscle wound repair requires the alignment and fusion of myoblasts to generate multinucleated myofibers. In vitro, the accurate quantification of cellular alignment remains a challenge. Here we present the application of ImageJ an
Publikováno v:
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair SocietyREFERENCES. 28(4)
The advancement of autologous mesenchymal stem cell (MSC) therapy for the treatment of non-healing diabetic wounds is hampered by endogenous MSC dysfunction and limited viability of cells post-transplantation into the pathological wound environment.
Publikováno v:
BioTechniques. 61:323-326
Myoblast fusion, which is essential for muscle development, regeneration, and repair, can be assessed in vitro via the calculation of a fusion index. Traditionally, this requires use of either immunocytochemistry or fluorescently-labeled cytoskeletal
Publikováno v:
Stem cells and development. 27(23)
Mesenchymal stem cells (MSCs) are a promising therapeutic tool for the treatment of nonhealing diabetic wounds. The pathological nature of the niche microenvironment limits the use of autologous cell therapy in diabetic patients. Prolonged exposure o
Autor:
Carola U. Niesler, Celia Snyman
Publikováno v:
Journal of Muscle Research and Cell Motility. 36:215-225
MMP-14 (also known as MT1-MMP) is a membrane-bound collagenase and member of the Matrix Metalloprotease (MMP) family known to target a broad range of extracellular matrix (ECM) proteins. Remodelling of the ECM is of particular importance following sk