Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Carola Steiger"'
Autor:
Bernd Schlereth, Mathias Locher, Pauline Wimberger, Benjamin Guller, Thomas Urbig, Sonja Offner, Ralf Lutterbuese, Robert Hofmeister, Andreas Wolf, Iduna Fichtner, Antonio J. da Silva, Rainer Kimmig, Tobias Raum, Peter Kufer, Klaus Brischwein, Carola Steiger, Petra Kleindienst, Patrick A. Baeuerle
Publikováno v:
Molecular Immunology. 43:1129-1143
We have developed a novel single-chain Ep-CAM-/CD3-bispecific single-chain antibody construct designated MT110. MT110 redirected unstimulated human peripheral T cells to induce the specific lysis of every Ep-CAM-expressing tumor cell line tested. MT1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7d079643e094e9acea1fe2996e2093e
https://doi.org/10.1016/j.molimm.2005.07.034
https://doi.org/10.1016/j.molimm.2005.07.034
Autor:
Francis V. Chisari, Carola Steiger, Robert Thimme, David W. Oldach, Kyong-Mi Chang, Stuart C. Ray
Publikováno v:
The Journal of Experimental Medicine
The virological and immunological features of hepatitis C virus (HCV) infection were studied weekly for 6 months after accidental needlestick exposure in five health care workers, four of whom developed acute hepatitis that progressed to chronicity w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::238998843e399c5c11da8ef66abd9f02
https://doi.org/10.1084/jem.194.10.1395
https://doi.org/10.1084/jem.194.10.1395
Autor:
A J da Silva, Klaus Brischwein, Nadja Prang, Carola Steiger, Patrick A. Baeuerle, A Wöppel, P Göster, J Müller, Susanne Preithner, M Peters
Publikováno v:
British Journal of Cancer
MT201 is a fully human monoclonal IgG1 antibody with moderate affinity for epithelial cell adhesion molecule (Ep-CAM) being clinically developed for the treatment of carcinomas. Like many other clinically validated IgG1 monoclonal antibodies, MT201 p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f68d5cbfb8de184a05c2d2fdf26bada1
https://pubmed.ncbi.nlm.nih.gov/15655555
https://pubmed.ncbi.nlm.nih.gov/15655555
Autor:
Carola Steiger, Keith A. Reimann, Stefan Wieland, Francis V. Chisari, Robert H. Purcell, John Ghrayeb, Robert Thimme
Although the CD4+- and CD8+-T-cell responses to the hepatitis B virus (HBV) are thought to be crucial for the control of HBV infection, the relative contribution of each T-cell subset as an effector of viral clearance is not known. To examine this qu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b454eb5eb7a9495b034206108336dab8
https://europepmc.org/articles/PMC140637/
https://europepmc.org/articles/PMC140637/
Autor:
Jens Bukh, Stefan Wieland, Robert Thimme, Francis V. Chisari, Carola Steiger, Robert H. Purcell, Sugantha Govindarajan, Janell Pemberton, Hans Christian Spangenberg
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 99(24)
To define the early events that determine the outcome of acute hepatitis C virus (HCV) infection, we compared the course of viremia with the peripheral and intrahepatic T cell response and intrahepatic cytokine profile in six acutely infected chimpan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee931298422099158354b715e2e8d0d9
https://pubmed.ncbi.nlm.nih.gov/12790129
https://pubmed.ncbi.nlm.nih.gov/12790129
Autor:
Doris Rau, Patrick A. Baeuerle, Carola Steiger, Peter Kufer, Patrick Hoffmann, Evelyn Ebert, Petra Meier, Tobias Raum, Susanne Mangold, Roman Kischel, Majk Kvesic, Susanne Hausmann, Susanne Strasser, Claudia Bluemel, Ronny Cierpka
Publikováno v:
Cancer Research. 70:2434-2434
BiTE antibodies are designed to transiently connect target cells with T cells of patients for induction of potent redirected lysis of cancer cells. Clinical proof-of-concept has been obtained with CD19/CD3-bispecific BiTE antibody blinatumomab (MT103
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c958177dcb28e9e52d84301f0108bffb
https://doi.org/10.1158/1538-7445.am10-2434
https://doi.org/10.1158/1538-7445.am10-2434