Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Carola Stegen"'
1
Serum- and glucocorticoid-dependent kinase, cell volume, and the regulation of epithelial transport
Autor: Ivano Moschèn, Siegfried Waldegger, Carsten A. Wagner, Iwan Setiawan, Stefan Bröer, S. Wärntges, J. Matskevitch, Florian Lang, Carola Stegen, Karin Klingel, Björn Friedrich, Stephan M. Huber, Sophie Fillon, Nikita Gamper, Y.X Feng, Alexey A. Vereninov
Publikováno v: Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology. 130:367-376
Ample pharmacological evidence points to a role of kinases in the regulation of cell volume. Given the limited selectivity of most inhibitors, however, the specific molecules involved have remained largely elusive. The search for cell volume regulate
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a41d655ae3bf74ff7ddfa6ac6fc38115
https://doi.org/10.1016/s1095-6433(01)00422-6
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2
Deranged transcriptional regulation of cell-volume-sensitive kinase hSGK in diabetic nephropathy
Autor: Karin Klingel, Martina Sauter, Volker Gerke, Björn Friedrich, Shaul G. Massry, Gerardo Gamba, Reinhard Kandolf, Markus Paulmichl, Florian Lang, M. Lanzendörfer, J. Melzig, Siegfried Waldegger, Silvia Steuer, Steven C. Hebert, Ivano Moschèn, Carola Stegen, Giovambattista Capasso, S. Wärntges, Stefan Bröer, Carsten A. Wagner, Teut Risler
Publikováno v: Proceedings of the National Academy of Sciences. 97:8157-8162
Transforming growth factor β (TGF-β) has been shown to participate in the pathophysiology of diabetic complications. As shown most recently, TGF-β stimulates the expression of a distinct serine/threonine kinase (hSGK) which had previously been clo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed2590e2a082c962d63f614b77f7af2c
https://doi.org/10.1073/pnas.97.14.8157
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3
Swelling-induced taurine release without chloride channel activity in Xenopus laevis oocytes expressing anion channels and transporters
Autor: Ioulia Matskevich, Florian Lang, Carola Stegen, Markus Paulmichl, Carsten A. Wagner, Stefan Bröer
Publikováno v: Biochimica et Biophysica Acta (BBA) - Biomembranes. 1467:91-100
Taurine is an important osmolyte involved in cell volume regulation. During regulatory volume decrease it is released via a volume-sensitive organic osmolyte/anion channel. Several molecules have been suggested as candidates for osmolyte release. In
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e09a883c04df70980f2abbe2289fc000
https://doi.org/10.1016/s0005-2736(00)00209-1
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4
Characterization of the high-affinity monocarboxylate transporter MCT2 in Xenopus laevis oocytes
Autor: Stefan BRÖER, Angelika BRÖER, Hans-Peter SCHNEIDER, Carola STEGEN, Andrew P. HALESTRAP, Joachim W. DEITMER
Publikováno v: Biochemical Journal. 341:529-535
Observations on lactate transport in brain cells and cardiac myocytes indicate the presence of a high-affinity monocarboxylate transporter. The rat monocarboxylate transporter isoform MCT2 was analysed by expression in Xenopus laevisoocytes and the r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::226e7e067088d48488e5162196ccdfcc
https://doi.org/10.1042/bj3410529
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5
[Untitled]
Autor: Wolfgang Roggendorf, Sven Wagner, Joerg-Christian Tonn, Klaus Roosen, Hakim Bouterfa, Carola Stegen, Claudia S. Huettner, Siglinde Kerkau
Publikováno v: Journal of Neuro-Oncology. 40:113-122
Matrix metalloproteinases have been implicated to play a vital role in glioma invasion as they degrade extracellular matrix to facilitate the subsequent migration of tumor cells into the surrounding brain tissue. The cytokine Interleukin-10 (IL-10) w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d67fac321c4ab7a0a889e81c12e57a53
https://doi.org/10.1023/a:1006146405880
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6
Acute regulation of the Betaine/GABA transporter BGT-1 expressed in xenopus oocytes by extracellular pH
Autor: Ioulia Matskevitch, Ivano Moschèn, Stefan Bröer, R.J.M. Bindels, Carsten A. Wagner, Carola Stegen, Florian Lang, C.H. van Os
Publikováno v: Kidney & Blood Pressure Research, 23, 6, pp. 356-359
Kidney & Blood Pressure Research, 23, 356-359
Scopus-Elsevier
Besides uptake of Na+ and Cl–, mammalian cells counteract osmotic cell shrinkage also by Na+-coupled uptake of osmolytes, e.g., myo-inositol, taurine or betaine. The expression of the corresponding transporters is transcriptionally regulated by the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03dcbac66eaed37a8405ea448a1450a9
https://hdl.handle.net/2066/186989
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