Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Carola Schiesling"'
Autor:
Carola Schiesling, Frank P. Marx, Olaf Riess, Christian Melle, Sabine Kautzmann, Simone Engelender, Anne S. Soehn, Thomas Franck, Daniela Berg, Jörg B. Schulz, Jens Pahnke, Karsten M. Strauss, Rejko Krüger, Simon Dawson, Ferdinand von Eggeling, Mira Lang
Publikováno v:
The FASEB Journal. 21:1759-1767
Synphilin-1 is linked to Parkinson's disease (PD), based on its role as an alpha-synuclein (PARK1)-interacting protein and substrate of the ubiquitin E3 ligase Parkin (PARK2) and because of its presence in Lewy bodies (LB) in brains of PD patients. W
Autor:
Dirk Woitalla, Ludger Schöls, Alfred Nordheim, Lena F. Burbulla, Doron Rapaport, Carola Schiesling, Olaf Riess, Thomas Illig, Peter Bauer, Stephan Jung, Manu Sharma, Hiroki Kato, Carina Schelling, Rejko Krüger, Claudia Schulte
Publikováno v:
Human molecular genetics 19(22), 4437-4452 (2010). doi:10.1093/hmg/ddq370
The mitochondrial chaperone mortalin has been linked to neurodegeneration in Parkinson's disease (PD) based on reduced protein levels in affected brain regions of PD patients and its interaction with the PD-associated protein DJ-1. Recently, two amin
Publikováno v:
Neuropathology and applied neurobiology. 34(3)
The identification of the first gene in familial Parkinson's disease (PD) only 10 years ago was a major step in the understanding of the molecular mechanisms in neurodegeneration. Alpha-synuclein aggregation was not only recognized as a key event in
Autor:
Rejko Krüger, Hans-Hermann Hoepken, Philipp J. Kahle, Andreas S. Reichert, Christian Haass, Iria Carballo-Carbajal, Carola Schiesling, Daniela Berg, Nicole Exner, Kira M. Holmström, Konstanze F. Winklhofer, Bettina Treske, Thomas Gasser, Georg Auburger, Bettina Schmid, Frank Vogel, Dominik Paquet, Suzana Gispert
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 27(45)
Degeneration of dopaminergic neurons in the substantia nigra is characteristic for Parkinson's disease (PD), the second most common neurodegenerative disorder. Mitochondrial dysfunction is believed to contribute to the etiology of PD. Although most c
Publikováno v:
Biotechnology progress. 22(5)
Metabolome analysis, the analysis of large sets of intracellular metabolites, has become an important systems analysis method in biotechnological and pharmaceutical research. In metabolic engineering, the integration of metabolome data with fluxome a
Publikováno v:
Biotechnology Progress; Oct2006, Vol. 22 Issue 5, p1434-1442, 9p