Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Carola S. Mehnert"'
Autor:
Wener Li, Michael Stauske, Xiaojing Luo, Stefan Wagner, Meike Vollrath, Carola S. Mehnert, Mario Schubert, Lukas Cyganek, Simin Chen, Sayed-Mohammad Hasheminasab, Gerald Wulf, Ali El-Armouche, Lars S. Maier, Gerd Hasenfuss, Kaomei Guan
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Brugada syndrome (BrS) is one of the major causes of sudden cardiac death in young people, while the underlying mechanisms are not completely understood. Here, we investigated the pathophysiological phenotypes and mechanisms using induced pluripotent
Externí odkaz:
https://doaj.org/article/67390607ff314c6cac21aee37e21a20f
Autor:
Juergen Graessler, Stefan R. Bornstein, S Strauss, S. Bergmann, Wong Ml, Carola S. Mehnert, Andreas L. Birkenfeld, Julio Licinio, T D Bornstein, K-M Schulte
Publikováno v:
The Pharmacogenomics Journal. 18:331-339
Urinary lipidomics may add new valuable biomarkers to the diagnostic armamentarium for early detection of metabolic and kidney diseases. Sources and composition of urinary lipids in healthy individuals, however, have not been investigated in detail.
Autor:
Susanne Kämmerer, Charlotte Schaeffer, Carola S. Mehnert, Stephanie M Schacht Wall, Karolina Sekeres, Ali El-Armouche, Stephan R Künzel, Manja Newe
Publikováno v:
Journal of Visualized Experiments.
Primary adult fibroblasts have become an important tool to study fibrosis, fibroblast interactions and inflammation in all body tissues. Since primary fibroblasts cannot divide indefinitely due to myofibroblast differentiation or senescence induction
Autor:
Stefan R. Bornstein, Carola S. Mehnert, Geltrude Mingrone, Lidia Castagneto Gissey, James Rossario Casella Mariolo, Virginia Kamvissi-Lorenz, Giovanni Casella, Juergen Graessler
Publikováno v:
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. 49(11)
The mechanisms behind the fast improvements of insulin sensitivity and release of the diabetic metabolic state after bariatric surgery are still not completely understood. To further elucidate the effects on the individual cellular level, we applied
Autor:
Silke Oeljeklaus, Lioba Kochbeck, Bernard Guiard, Bettina Warscheid, Carola S. Mehnert, Michael Gebert, Sandra G. Schrempp, Heike Rampelt, Martin van der Laan
Publikováno v:
Journal of Biological Chemistry. 289:27352-27362
The majority of mitochondrial proteins are synthesized with amino-terminal signal sequences. The presequence translocase of the inner membrane (TIM23 complex) mediates the import of these preproteins. The essential TIM23 core complex closely cooperat
Autor:
Karina von der Malsburg, Martin van der Laan, Sebastian Wiese, Raffaele Ieva, Maria Bohnert, Bernard Guiard, Ilka Haferkamp, Anna K. Heißwolf, Silke Oeljeklaus, Carola Hunte, Nikolaus Pfanner, Sandra G. Schrempp, Helmut E. Meyer, Carola S. Mehnert, Thomas Kleinschroth, Bettina Warscheid, Michael Gebert
Publikováno v:
The Journal of Cell Biology
Mgr2 is a new component of the mitochondrial presequence translocase required for efficient coupling of the TIM23 core complex to Tim21, respiratory chain complexes, and the translocase of the outer mitochondrial membrane.
Many mitochondrial pro
Many mitochondrial pro
Autor:
Carola S. Mehnert, Florian Wollweber, Raffaele Ieva, F.-Nora Vögtle, Martin van der Laan, Michael Gebert, Anna K. Heißwolf, Chris Meisinger, Silke Oeljeklaus, Bettina Warscheid, Nikolaus Pfanner
Publikováno v:
Nature Communications
Nature Communications, Nature Publishing Group, 2013, 4, ⟨10.1038/ncomms3853⟩
Nature Communications, Nature Publishing Group, 2013, 4, ⟨10.1038/ncomms3853⟩
International audience; The presequence translocase of the inner mitochondrial membrane (TIM23 complex) is essential for importing cleavable preproteins into mitochondria. The preproteins contain amino-terminal targeting sequences that are removed by
Publikováno v:
The FASEB Journal. 26
Autor:
Nils Wiedemann, Martin van der Laan, Agnieszka Chacinska, Chris Meisinger, Carola S. Mehnert, Dana P. Hutu, David U. Mick, Peter Rehling, Bernard Guiard, Nikolaus Pfanner, Kaye N. Truscott
Mitochondrial import of cleavable preproteins occurs at translocation contact sites, where the translocase of the outer membrane (TOM) associates with the presequence translocase of the inner membrane (TIM23) in a supercomplex. Different views exist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50cd369d30d4a67971909ba3ec9f0b74
https://europepmc.org/articles/PMC2798301/
https://europepmc.org/articles/PMC2798301/
Autor:
Martin van der Laan, Nikolaus Pfanner, Michael Gebert, Sandra G. Schrempp, Anna K. Heißwolf, Maria Bohnert, Raffaele Ieva, Carola S. Mehnert
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1817:S70-S71