Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Carola Pongratz"'
Autor:
Carola Pongratz, Benjamin Yazdanpanah, Hamid Kashkar, Maik J Lehmann, Hans-Georg Kräusslich, Martin Krönke
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13172 (2010)
RNA interference (RNAi) has been considered as an efficient therapeutic approach against the human immunodeficiency virus type 1 (HIV-1). However, to establish a durable inhibition of HIV-1, multiple effective short hairpin RNAs (shRNAs) need to be s
Externí odkaz:
https://doaj.org/article/dc8f010013af4309bf754b005fde4b6f
Autor:
Olaf Utermöhlen, Martina Deckert, Daniela Wenzel, Franziska Peters, Carola Pongratz, Wolfram Doehner, Martin Krönke, Bettina Tosetti, Susanne Brodesser, Matthias Blüher, Bernd K. Fleischmann, Stefan D. Anker, Anna Brunn
Publikováno v:
Aging Cell
Loss of skeletal muscle mass is one of the most widespread and deleterious processes in aging humans. However, the mechanistic metabolic principles remain poorly understood. In the framework of a multi‐organ investigation of age‐associated change
Autor:
Nikola Baschuk, D Haubert, Cristian Dan Neacsu, Olaf Utermöhlen, Hamid Kashkar, Carola Pongratz, Martin Krönke, A Boecke, A C Carstens
Publikováno v:
British Journal of Cancer
It has become apparent that tumours are complex ecologies of different cell types and that the full manifestation of the malignant potential of transformed epithelial cells requires an appropriate support structure from the stroma. Haematopoietic cel
Autor:
Carola Pongratz, Jens M. Seeger, Benjamin Yazdanpanah, Dirk Haubert, Hamid Kashkar, Martin Krönke, Oliver Coutelle, Kerstin Brinkmann
Publikováno v:
British Journal of Cancer
Background: In various tumour types, elevated expression of the X-linked inhibitor of apoptosis protein (XIAP) has been observed and XIAP targeting in diverse tumour entities enhanced the susceptibility to chemotherapeutic agents. Therefore, XIAP has
Autor:
Michael Schramm, Vladimir Tchikov, Hamid Kashkar, Katja Wiegmann, Martin Krönke, Olaf Utermöhlen, Oleg Krut, Stefan Schütze, Benjamin Yazdanpanah, Carola Pongratz, Jens C. Brüning, André Kleinridders, Thomas F. Wunderlich
Publikováno v:
Nature. 460:1159-1163
Riboflavin kinase has been identified as a novel interacting partner for the death domain of receptor-1 for tumour necrosis factor (TNF-R1). It is required to recruit to and functionally couple p22phox to TNF-R1. As p22phox is the catalytic subunit o
Autor:
Maria Andree, Rudolf J. Wiesner, Saskia Diana Günther, Stephan Schüll, Kerstin Brinkmann, F Diaz, Jens M. Seeger, Carola Pongratz, Hamid Kashkar, Susanne Brodesser, Martin Krönke, Katja Wiegmann, Axel Witt, Bettina Tosetti
Publikováno v:
Cell Death & Disease
Although numerous pathogenic changes within the mitochondrial respiratory chain (RC) have been associated with an elevated occurrence of apoptosis within the affected tissues, the mechanistic insight into how mitochondrial dysfunction initiates apopt
Autor:
Martin Krönke, Anke Deggerich, Carola Pongratz, Dirk Haubert, Katja Wiegmann, Hamid Kashkar, Jens-Michael Seeger, Benjamin Yazdanpanah
Publikováno v:
Blood. 109(9)
The proteasome inhibitor bortezomib has been shown to possess promising antitumor activity and significant efficacy against a variety of malignancies. Different studies demonstrated that bortezomib breaks the chemoresistance in different tumor cells
Autor:
Francisco Rivero, Oleg Krut, Katja Wiegmann, Martin Krönke, Carola Pongratz, Dietmar M. Theisen
Publikováno v:
Vaccine. 24(16)
Human immunodeficiency virus type 1-encoded Tat protein is a transactivating factor essentially required for viral replication. Tat binds specifically to the transactivation response RNA stem loop, which is formed at the 5' end of all viral transcrip
Autor:
Martin Krönke, Carola Pongratz, Hans-Georg Kräusslich, Maik J. Lehmann, Benjamin Yazdanpanah, Hamid Kashkar
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13172 (2010)
PLoS ONE
PLoS ONE
RNA interference (RNAi) has been considered as an efficient therapeutic approach against the human immunodeficiency virus type 1 (HIV-1). However, to establish a durable inhibition of HIV-1, multiple effective short hairpin RNAs (shRNAs) need to be s