Zobrazeno 1 - 10
of 137
pro vyhledávání: '"Carola Meier"'
Autor:
Ewa Wisniewska, Dominik Laue, Jacob Spinnen, Leonard Kuhrt, Benjamin Kohl, Patricia Bußmann, Carola Meier, Gundula Schulze-Tanzil, Wolfgang Ertel, Michal Jagielski
Publikováno v:
Cells, Vol 12, Iss 24, p 2850 (2023)
Osteoarthritis (OA) most frequently affects the knee joint and is associated with an elevated expression of cytokines and extracellular cartilage matrix (ECM), degrading enzymes such as matrix metalloproteinases (MMPs). Differences in gene expression
Externí odkaz:
https://doaj.org/article/0577b15e6d0a4188ab9205d56ed7345e
Autor:
Patrick Carius, Annemarie Jungmann, Marco Bechtel, Alexander Grißmer, Annette Boese, Gilles Gasparoni, Abdulrahman Salhab, Ralf Seipelt, Klaus Urbschat, Clémentine Richter, Carola Meier, Denisa Bojkova, Jindrich Cinatl, Jörn Walter, Nicole Schneider‐Daum, Claus‐Michael Lehr
Publikováno v:
Advanced Science, Vol 10, Iss 8, Pp n/a-n/a (2023)
Abstract In the development of orally inhaled drug products preclinical animal models regularly fail to predict pharmacological as well as toxicological responses in humans. Models based on human cells and tissues are potential alternatives to animal
Externí odkaz:
https://doaj.org/article/bd657f46b48c4b599d1780adf01cc0eb
Autor:
Colya N. Englisch, Daniel Röhricht, Mariesa Walz, Kerstin Junker, Anja Beckmann, Carola Meier, Friedrich Paulsen, Martin Jung, Thomas Tschernig
Publikováno v:
International Journal of Translational Medicine, Vol 2, Iss 2, Pp 156-163 (2022)
In the context of renal proteinuric diseases, TRPC6 has been shown to play an important role in ultrafiltration associated with the slit diaphragm through the control of the intracellular Ca2+ concentration in the podocytes of glomeruli. However, to
Externí odkaz:
https://doaj.org/article/50a454c56287497895be7cf00a5dfe56
Autor:
Li-Pao Fang, Na Zhao, Laura C. Caudal, Hsin-Fang Chang, Renping Zhao, Ching-Hsin Lin, Nadine Hainz, Carola Meier, Bernhard Bettler, Wenhui Huang, Anja Scheller, Frank Kirchhoff, Xianshu Bai
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Early postnatal interruption of the bidirectional GABA/TNFSF12 signaling between parvalbumin-positive interneurons and oligodendrocyte precursor cells impairs correct prefrontal cortical network activity and social cognitive behavior later in life.
Externí odkaz:
https://doaj.org/article/2d0a09c506374f3cb705f43e9434264f
Autor:
Yiwen Yao, Richard F. Sprott, Felix Ritzmann, Alexander Grißmer, Frank Langer, Christian Herr, Carola Meier, Robert Bals, Christoph Beisswenger, Thomas Tschernig
Publikováno v:
Translational Research in Anatomy, Vol 26, Iss , Pp 100169- (2022)
Background: For translational research on lung diseases it is desirable to have human organoids which resemble features of human tissue. Adult stem cells obtained from human bronchial epithelium can be differentiated to little tissue follicles, so-ca
Externí odkaz:
https://doaj.org/article/e80319896f4b445ebc2e4f9599d4f76b
Autor:
Leonie Schumacher, Rédouane Slimani, Laimdota Zizmare, Jakob Ehlers, Felix Kleine Borgmann, Julia C. Fitzgerald, Petra Fallier-Becker, Anja Beckmann, Alexander Grißmer, Carola Meier, Ali El-Ayoubi, Kavi Devraj, Michel Mittelbronn, Christoph Trautwein, Ulrike Naumann
Publikováno v:
Biomedicines, Vol 11, Iss 1, p 214 (2023)
The blood–brain barrier (BBB) is a selectively permeable boundary that separates the circulating blood from the extracellular fluid of the brain and is an essential component for brain homeostasis. In glioblastoma (GBM), the BBB of peritumoral vess
Externí odkaz:
https://doaj.org/article/18089ef200924f798e582be6d234a2b9
Autor:
Robert Richter, Mohamed.A.M. Kamal, Mariel A. García-Rivera, Jerome Kaspar, Maximilian Junk, Walid A.M. Elgaher, Sanjay Kumar Srikakulam, Alexander Gress, Anja Beckmann, Alexander Grißmer, Carola Meier, Michael Vielhaber, Olga Kalinina, Anna K.H. Hirsch, Rolf W. Hartmann, Mark Brönstrup, Nicole Schneider-Daum, Claus-Michael Lehr
Publikováno v:
Materials Today Bio, Vol 8, Iss , Pp 100084- (2020)
The pipeline of antibiotics has been for decades on an alarmingly low level. Considering the steadily emerging antibiotic resistance, novel tools are needed for early and easy identification of effective anti-infective compounds. In Gram-negative bac
Externí odkaz:
https://doaj.org/article/abcd928f0e8c4f0e83637af5a24dae36
Autor:
Nadine Hainz, Anja Beckmann, Madline Schubert, Alexandra Haase, Ulrich Martin, Thomas Tschernig, Carola Meier
Publikováno v:
BMC Research Notes, Vol 11, Iss 1, Pp 1-6 (2018)
Abstract Objective Pannexins are channel proteins important for the release of calcium and adenosine triphosphate, which are among other functions involved in early development. Here, the expression of pannexins was investigated in induced pluripoten
Externí odkaz:
https://doaj.org/article/056266e5ab3543aaaa3721b381ebf25c
Publikováno v:
Biology, Vol 10, Iss 12, p 1307 (2021)
In a short-term model of hyperosmotic stress, primary murine astrocytes were stimulated with a hyperosmolar sucrose solution for five minutes. Astrocytic gap junctions, which are mainly composed of Connexin (Cx) 43, displayed immediate ultrastructura
Externí odkaz:
https://doaj.org/article/54390a3581a7444d8dd6a3bfb38079c4
Autor:
Linda Pätzold, Alexandra Stark, Felix Ritzmann, Carola Meier, Thomas Tschernig, Jörg Reichrath, Robert Bals, Markus Bischoff, Christoph Beisswenger
Publikováno v:
Microorganisms, Vol 9, Iss 9, p 1821 (2021)
The epithelial cytokine interleukin-17C (IL-17C) mediates inflammation through the interleukin 17 receptor E (IL-17RE). Prior studies showed a detrimental role of IL-17C in the pathogenesis of immune-mediated skin diseases (e.g., psoriasis). Here, we
Externí odkaz:
https://doaj.org/article/e1bb075ffbe54ab89efa598ad219fb22