Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Carola Krüger"'
Autor:
Ángel J. Picher, Bettina Budeus, Oliver Wafzig, Carola Krüger, Sara García-Gómez, María I. Martínez-Jiménez, Alberto Díaz-Talavera, Daniela Weber, Luis Blanco, Armin Schneider
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
Single cell genomic analysis needs DNA amplification with high fidelity and accuracy. Here, the authors devise a novel multiple displacement amplification method called TruePrime that is based in Thermus thermophilusPrimPol and Phi29 DNA polymerase,
Externí odkaz:
https://doaj.org/article/7684ce22eed44d1aa7aa7d8f45a853bc
Autor:
Andreas Rogalewski, Tanjew Dittgen, Matthias Klugmann, Friederike Kirsch, Carola Krüger, Claudia Pitzer, Jens Minnerup, Wolf-Rüdiger Schäbitz, Armin Schneider
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10737 (2010)
BACKGROUND: We have previously identified Semaphorin 6a (Sema6A) as an upregulated gene product in a gene expression screen in cortical ischemia [1]. Semaphorin 6a was regulated during the recovery phase following ischemia in the cortex. Semaphorin 6
Externí odkaz:
https://doaj.org/article/f90dde209fca4067960c6483a5476122
Autor:
Shyon Haghpeykar, Jean M. Hansen, Rebecca L. Stone, Chiyi Xiong, Alpa M. Nick, Sunila Pradeep, Kshipra M. Gharpure, Gabriel Lopez-Berestein, Guillermo N. Armaiz-Pena, Mien Chie Hung, Chun Li, Edna M. Mora, Cristian Rodriguez-Aguayo, Sherry Y. Wu, Archana S. Nagaraja, Martin Stein, Hee Dong Han, Rebecca A. Previs, Anil K. Sood, Blake W. Goodman, Kyunghee Noh, Masato Nishimura, Robert L. Coleman, Armin Schneider, Min Soon Cho, Chad V. Pecot, Rajesha Rupaimoole, Jie Huang, Lingegowda S. Mangala, Bulent Ozpolat, Yunfei Wen, Jinsong Liu, Pablo E. Vivas-Mejia, Stephan Brock, Padmavathi Jaladurgam, John E. Ladbury, Diana L. Urbauer, Koji Matsuo, Heather J. Dalton, Carola Krüger, Christopher G. Danes, David B. Jackson, Loren J. Stagg, Wei Hu, Behrouz Zand, S. Neslihan Alpay
Publikováno v:
Cancer Cell. 28(5):610-622
SummaryWhile recombinant human erythropoietin (rhEpo) has been widely used to treat anemia in cancer patients, concerns about its adverse effects on patient survival have emerged. A lack of correlation between expression of the canonical EpoR and rhE
Autor:
Martin H. Maurer, Heinrich F. Bürgers, Carola Krüger, Bach Alfred, Dominik W. Schelshorn, Wolfgang Kuschinsky, Tanjew Dittgen, Armin Schneider, Fatemeh Sabouri, Nikolaus Gassler, Daniela Weber
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 29:585-595
Hemoglobin is the major protein in red blood cells and transports oxygen from the lungs to oxygen-demanding tissues, like the brain. Mechanisms that facilitate the uptake of oxygen in the vertebrate brain are unknown. In invertebrates, neuronal hemog
Autor:
Alfred Bach, Christian Plaas, Hannelore Ehrenreich, Wolf-Rüdiger Schäbitz, Friederike Kirsch, Robert Spoelgen, Claudia Pitzer, Stefan Kastner, Armin Schneider, Carola Krüger, Alexandre Henriques, Rico Laage, Ralph Müller, Stefanie Suess, Tanjew Dittgen
Publikováno v:
Brain
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease that results in progressive loss of motoneurons, motor weakness and death within 1-5 years after disease onset. Therapeutic options remain limited despite a substantial nu
Autor:
Carola Krüger, Armin Schneider, Ming Fei Lang, Markus Schwaninger, Roland M. Schmid, Roman Dziarski
Publikováno v:
Neuroscience Letters. 430:138-141
Cerebral ischemia triggers inflammation and apoptosis, and the transcription factor NF-kappaB is a key regulator of both events. Here, we report on the induction of the peptidoglycan recognition protein-S (PGRP-S) in a mouse model of cerebral ischemi
Autor:
Nikolaus Gassler, Rico Laage, Jaroslaw Aronowski, Daniela Weber, Armin Schneider, Tanjew Dittgen, Bach Alfred, Friederike Kirsch, Clemens Sommer, Walter Mier, Claudia Pitzer, Carola Krüger, Wolf Rüdiger Schäbitz
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 28:29-43
Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a hematopoietic cytokine responsible for the proliferation, differentiation, and maturation of cells of the myeloid lineage, which was cloned more than 20 years ago. Here we uncovered a nov
Autor:
Achim Fischer, Armin Schneider, Clemens Sommer, Carola Krüger, Wolf-Rüdiger Schäbitz, Durmus Cira
Publikováno v:
Experimental Neurology. 200:135-152
Cerebral ischemia evokes changes in gene expression time-dependently after the ischemic event. Most studies on transcriptional changes following ischemia have centered on relatively early postischemic time points, and detected multiple genes relevant
Autor:
Rico Laage, Jochen H. Weishaupt, Paul Lingor, Katrin Meuer, Bettina Göricke, Armin Schneider, Wolf-Rüdiger Schäbitz, Carola Krüger, Johannes C. M. Schlachetzki, Kerstin Peters, Bach Alfred, Jörg B. Schulz, Daniela Weber, Boris Ferger, Kazuto Kobayashi, Peter Teismann, Gunnar P.H. Dietz, Claudia Pitzer, Mathias Bähr
Publikováno v:
Journal of Neurochemistry. 97:675-686
We have recently shown that the hematopoietic Granulocyte-Colony Stimulating Factor (G-CSF) is neuroprotective in rodent stroke models, and that this action appears to be mediated via a neuronal G-CSF receptor. Here, we report that the G-CSF receptor
Publikováno v:
Molecular Brain Research. 124:20-28
Cerebral ischemia induces transcriptional changes in a number of pathophysiologically important genes. Here we have systematically studied gene expression changes in the cortex after 150 min of focal cortical ischemia and 2 and 6 h reperfusion in the