Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Carola I, Radulescu"'
Autor:
Erik Nutma, Nurun Fancy, Maria Weinert, Stergios Tsartsalis, Manuel C. Marzin, Robert C. J. Muirhead, Irene Falk, Marjolein Breur, Joy de Bruin, David Hollaus, Robin Pieterman, Jasper Anink, David Story, Siddharthan Chandran, Jiabin Tang, Maria C. Trolese, Takashi Saito, Takaomi C. Saido, Katharine H. Wiltshire, Paula Beltran-Lobo, Alexandra Phillips, Jack Antel, Luke Healy, Marie-France Dorion, Dylan A. Galloway, Rochelle Y. Benoit, Quentin Amossé, Kelly Ceyzériat, Aurélien M. Badina, Enikö Kövari, Caterina Bendotti, Eleonora Aronica, Carola I. Radulescu, Jia Hui Wong, Anna M. Barron, Amy M. Smith, Samuel J. Barnes, David W. Hampton, Paul van der Valk, Steven Jacobson, Owain W. Howell, David Baker, Markus Kipp, Hannes Kaddatz, Benjamin B. Tournier, Philippe Millet, Paul M. Matthews, Craig S. Moore, Sandra Amor, David R. Owen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-25 (2023)
Abstract Microglial activation plays central roles in neuroinflammatory and neurodegenerative diseases. Positron emission tomography (PET) targeting 18 kDa Translocator Protein (TSPO) is widely used for localising inflammation in vivo, but its quanti
Externí odkaz:
https://doaj.org/article/6e4226618e024c669f4f230499a8801b
Autor:
Thomas Knöpfel, Yann Sweeney, Carola I. Radulescu, Nawal Zabouri, Nazanin Doostdar, Claudia Clopath, Samuel J. Barnes
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Sensory stimuli usually arrive simultaneously but the neural-circuit mechanisms that combine multiple streams of sensory information are incompletely understood. The authors here show that visual-auditory pairing drives plasticity in multi-modal neur
Externí odkaz:
https://doaj.org/article/b59fcdd02a4047f1b6117f7a8958b6d5
Autor:
Carola I. Radulescu, Marta Garcia-Miralles, Harwin Sidik, Costanza Ferrari Bardile, Nur Amirah Binte Mohammad Yusof, Hae Ung Lee, Eliza Xin Pei Ho, Collins Wenhan Chu, Emma Layton, Donovan Low, Paola Florez De Sessions, Sven Pettersson, Florent Ginhoux, Mahmoud A. Pouladi
Publikováno v:
Neurobiology of Disease, Vol 127, Iss , Pp 65-75 (2019)
Structural and molecular myelination deficits represent early pathological features of Huntington disease (HD). Recent evidence from germ-free (GF) animals suggests a role for microbiota-gut-brain bidirectional communication in the regulation of myel
Externí odkaz:
https://doaj.org/article/57a94a7b970649ec909b982d493a2399
Autor:
Carola I. Radulescu, Marta Garcia-Miralles, Harwin Sidik, Costanza Ferrari Bardile, Nur Amirah Binte Mohammad Yusof, Hae Ung Lee, Eliza Xin Pei Ho, Collins Wenhan Chu, Emma Layton, Donovan Low, Paola Florez De Sessions, Sven Pettersson, Florent Ginhoux, Mahmoud A. Pouladi
Publikováno v:
Neurobiology of Disease, Vol 135, Iss , Pp 104744- (2020)
Structural and molecular myelination deficits represent early pathological features of Huntington disease (HD). Recent evidence from germ-free (GF) animals suggests a role for microbiota-gut-brain bidirectional communication in the regulation of myel
Externí odkaz:
https://doaj.org/article/7120aaec36004d4c8dc6c5ba2b8ffd5c
Autor:
Abbas, Dehghan, Rui Climaco, Pinto, Ibrahim, Karaman, Jian, Huang, Brenan R, Durainayagam, Mohsen, Ghanbari, Areesha, Nazeer, Qi, Zhong, Sonia, Liggi, Luke, Whiley, Rima, Mustafa, Miia, Kivipelto, Alina, Solomon, Tiia, Ngandu, Takahisa, Kanekiyo, Tomonori, Aikawa, Carola I, Radulescu, Samuel J, Barnes, Gonçalo, Graça, Elena, Chekmeneva, Stephane, Camuzeaux, Matthew R, Lewis, Manuja R, Kaluarachchi, M Arfan, Ikram, Elaine, Holmes, Ioanna, Tzoulaki, Paul M, Matthews, Julian L, Griffin, Paul, Elliott
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(43)
Genome-wide association studies (GWASs) have identified genetic loci associated with the risk of Alzheimer's disease (AD), but the molecular mechanisms by which they confer risk are largely unknown. We conducted a metabolome-wide association study (M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::44758504b5724d9b2d5c5ea4c29cba19
https://pubmed.ncbi.nlm.nih.gov/36269859
https://pubmed.ncbi.nlm.nih.gov/36269859
Autor:
Abbas Dehghan, Rui Climaco Pinto, Ibrahim Karaman, Jian Huang, Brenan R. Durainayagam, Mohsen Ghanbari, Areesha Nazeer, Qi Zhong, Sonia Liggi, Luke Whiley, Rima Mustafa, Miia Kivipelto, Alina Solomon, Tiia Ngandu, Takahisa Kanekiyo, Tomonori Aikawa, Carola I. Radulescu, Samuel J. Barnes, Gonçalo Graça, Elena Chekmeneva, Stephane Camuzeaux, Matthew R. Lewis, Manuja R. Kaluarachchi, M. Arfan Ikram, Elaine Holmes, Ioanna Tzoulaki, Paul M. Matthews, Julian L. Griffin, Paul Elliott
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 119(43):e2206083119. National Academy of Sciences
Genome-wide association studies (GWASs) have identified genetic loci associated with the risk of Alzheimer’s disease (AD), but the molecular mechanisms by which they confer risk are largely unknown. We conducted a metabolome-wide association study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::673c19cb621adb590cf6d6076a05edd5
http://hdl.handle.net/10044/1/100823
http://hdl.handle.net/10044/1/100823
Autor:
Erik Nutma, Nurun Fancy, Maria Weinert, Manuel C. Marzin, Stergios Tsartsalis, Robert C.J. Muirhead, Irene Falk, Joy de Bruin, David Hollaus, Robin Pieterman, Jasper Anink, David Story, Siddharthan Chandran, Jiabin Tang, Maria C. Trolese, Takashi Saito, Takaomi C. Saido, Katie Wiltshire, Paula Beltran-Lobo, Alexandra Philips, Jack Antel, Luke Healy, Craig S. Moore, Caterina Bendotti, Eleonora Aronica, Carola I. Radulescu, Samuel J. Barnes, David W. Hampton, Paul van der Valk, Steven Jacobson, Paul M. Matthews, Sandra Amor, David R. Owen
Microglial activation plays central roles in neuro-inflammatory and neurodegenerative diseases. Positron emission tomography (PET) targeting 18kDa Translocator Protein (TSPO) is widely used for localising inflammation in vivo, but its quantitative in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8719241c8e97acc9b023c673aa4e81fa
https://doi.org/10.1101/2022.05.11.491453
https://doi.org/10.1101/2022.05.11.491453
Autor:
Samuel J. Barnes, Carola I. Radulescu
Publikováno v:
Current Biology. 31:R721-R723
Summary A new study explores the neural-circuit and synaptic processes that support the transition from general to specific aversive memory formation. A critical role for homeostatic synaptic down-scaling in shaping the specificity of an associative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0bb9c9abe60fece7e8febafbdec92499
https://doi.org/10.1016/j.cub.2021.04.023
https://doi.org/10.1016/j.cub.2021.04.023
Autor:
Nawal Zabouri, Samuel J. Barnes, Nazanin Doostdar, Yann Sweeney, Claudia Clopath, Carola I. Radulescu, Thomas Knöpfel
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Nature Communications
Nature Communications
We experience the world through multiple senses simultaneously. To better understand mechanisms of multisensory processing we ask whether inputs from two senses (auditory and visual) can interact and drive plasticity in neural-circuits of the primary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67e87e705769c87be70575a3ec14a028
http://link.springer.com/article/10.1038/s41467-019-13607-2
http://link.springer.com/article/10.1038/s41467-019-13607-2
Autor:
Leire Melgosa-Ecenarro, Nazanin Doostdar, Carola I. Radulescu, Johanna S. Jackson, Samuel J. Barnes
Publikováno v:
Seminars in celldevelopmental biology. 139
The early stages of Alzheimer's disease (AD) have been linked to microcircuit dysfunction and pathophysiological neuronal firing in several brain regions. Inhibitory GABAergic microcircuitry is a critical feature of stable neural-circuit function in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a9bbb5c2d679d8afbd3ae8d7a958777
https://pubmed.ncbi.nlm.nih.gov/35963663
https://pubmed.ncbi.nlm.nih.gov/35963663