Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Carola, Leuschner"'
Autor:
Yun Hu, Sébastien Paris, Narayan Sahoo, Qi Wang, Qianxia Wang, Hampartsoum B. Barsoumian, Ailing Huang, Jordan Da Silva, Célia Bienassis, Claudia S. Kettlun Leyton, Tiffany A. Voss, Fatemeh Masrorpour, Thomas Riad, Carola Leuschner, Nahum Puebla-Osorio, Saumil Gandhi, Quynh-Nhu Nguyen, Jing Wang, Maria Angelica Cortez, James W. Welsh
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-22 (2024)
Abstract Recent findings suggest that immunoradiotherapy (IRT), combining photon radiotherapy (XRT) or proton radiotherapy (PRT) with immune checkpoint blockade, can enhance systemic tumor control. However, the comparative efficacy of XRT and PRT in
Externí odkaz:
https://doaj.org/article/3c08becd51c4497faf642983fc0d91a9
Autor:
Nahum Puebla-Osorio, Natalie Wall Fowlkes, Hampartsoum B. Barsoumian, Kristina Xega, Gitika Srivastava, Claudia Kettlun-Leyton, Sara Nizzero, Tiffany Voss, Thomas S. Riad, Christina Wong, Ailing Huang, Yun Hu, Joylise Mitchell, Mingee Kim, Zahid Rafiq, Kewen He, Duygu Sezen, Ethan Hsu, Fatemeh Masrorpour, Aurian Maleki, Carola Leuschner, Maria Angelica Cortez, Philipp Oertle, Marko Loparic, Marija Plodinec, Janet L. Markman, James W. Welsh
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionEffective infiltration of chimeric antigen receptor T (CAR-T) cells into solid tumors is critical for achieving a robust antitumor response and improving therapeutic outcomes. While CAR-T cell therapies have succeeded in hematologic malig
Externí odkaz:
https://doaj.org/article/e15d8e28463245d5a2e2e3d70c939f5b
Autor:
Yun Hu, Alexey Revenko, Hampartsoum Barsoumian, Genevieve Bertolet, Natalie Wall Fowlkes, Hadi Maazi, Morgan Maureen Green, Kewen He, Duygu Sezen, Tiffany A. Voss, Claudia S Kettlun Leyton, Fatemeh Masrorpour, Zahid Rafiq, Nahum Puebla-Osorio, Carola Leuschner, Robert MacLeod, Maria Angelica Cortez, James W. Welsh
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-15 (2024)
Abstract Background The combination of radiotherapy and immunotherapy (immunoradiotherapy) has been increasingly used for treating a wide range of cancers. However, some tumors are resistant to immunoradiotherapy. We have previously shown that MER pr
Externí odkaz:
https://doaj.org/article/bfe32f32799d4d64804e7e64eb090fe4
Autor:
Yun Hu, Sébastien Paris, Genevieve Bertolet, Hampartsoum B. Barsoumian, Kewen He, Duygu Sezen, Dawei Chen, Mark Wasley, Jordan DA SILVA, Joylise A. Mitchell, Tiffany A. Voss, Fatemeh Masrorpour, Claudia Kettlun Leyton, Liangpeng Yang, Carola Leuschner, Nahum Puebla-Osorio, Saumil Gandhi, Quynh-Nhu Nguyen, Maria Angelica Cortez, James W. Welsh
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-19 (2022)
Abstract Background While improvements in immunoradiotherapy have significantly improved outcomes for cancer patients, this treatment approach has nevertheless proven ineffective at controlling the majority of malignancies. One of the mechanisms of r
Externí odkaz:
https://doaj.org/article/a090d791bef0465c93bf5eb25e2451f7
Autor:
Yun Hu, Sébastien Paris, Narayan Sahoo, Genevieve Bertolet, Qi Wang, Qianxia Wang, Hampartsoum B. Barsoumian, Jordan Da Silva, Ailing Huang, Denaha J. Doss, David P. Pollock, Ethan Hsu, Nanez Selene, Claudia S. Kettlun Leyton, Tiffany A. Voss, Fatemeh Masrorpour, Shonik Ganjoo, Carola Leuschner, Jordan T. Pietz, Nahum Puebla-Osorio, Saumil Gandhi, Quynh-Nhu Nguyen, Jing Wang, Maria Angelica Cortez, James W. Welsh
Publikováno v:
JCI Insight, Vol 8, Iss 12 (2023)
The combination of radiation therapy (RT) and immunotherapy has emerged as a promising treatment option in oncology. Historically, x-ray radiation (XRT) has been the most commonly used form of RT. However, proton beam therapy (PBT) is gaining recogni
Externí odkaz:
https://doaj.org/article/9723583757f443f79537c57a412f592b
Autor:
Yun Hu, Sébastien Paris, Genevieve Bertolet, Hampartsoum B. Barsoumian, Qi Wang, Jordan Da Silva, Nalini B. Patel, Nguyen Nguyen, Denaha J. Doss, Ailing Huang, Ethan Hsu, Claudia S. Kettlun Leyton, Tiffany A. Voss, Fatemeh Masrorpour, Carola Leuschner, Jordan T. Pietz, Nahum Puebla-Osorio, Saumil Gandhi, Quynh-Nhu Nguyen, Jing Wang, Maria Angelica Cortez, James W. Welsh
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The efficacy of immunoradiotherapy consisting of radiation therapy and immune checkpoint blockade relies on effectively promoting the systemic antitumor immune response’s activation while simultaneously reducing local factors favoring immune suppre
Externí odkaz:
https://doaj.org/article/b52124ce446c4e9989debf373cb9acaf
Autor:
Kewen He, Hampartsoum B. Barsoumian, Genevieve Bertolet, Vivek Verma, Carola Leuschner, Eugene J. Koay, Ethan B. Ludmir, Ethan Hsu, Esha Pisipati, Tiffany A. Voss, Nahum Puebla-Osorio, Maria Angelica Cortez, James W. Welsh
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Despite multiple therapeutic approaches, the presence of liver metastases carries a guarded prognosis, urgently necessitating further clinical and scientific research to develop curative interventions. The liver is an immunoprivileged organ that supp
Externí odkaz:
https://doaj.org/article/e149c14bb5724d3ea8bd7bd9998f2233
Autor:
Kewen He, Hampartsoum B. Barsoumian, Nahum Puebla-Osorio, Yun Hu, Duygu Sezen, Mark D. Wasley, Genevieve Bertolet, Jie Zhang, Carola Leuschner, Liangpeng Yang, Claudia S. Kettlun Leyton, Natalie Wall Fowlkes, Morgan Maureen Green, Lisa Hettrick, Dawei Chen, Fatemeh Masrorpour, Meidi Gu, Hadi Maazi, Alexey S. Revenko, Maria Angelica Cortez, James W. Welsh
Publikováno v:
Cancer Immunology Research. 11:486-500
Diverse factors contribute to the limited clinical response to radiotherapy (RT) and immunotherapy in metastatic non–small cell lung cancer (NSCLC), among which is the ability of these tumors to recruit a retinue of suppressive immune cells—such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eae04614541ce88205150bb063becca8
https://doi.org/10.1158/2326-6066.cir-22-0547
https://doi.org/10.1158/2326-6066.cir-22-0547
Autor:
James W. Welsh, Maria Angelica Cortez, Alexey S. Revenko, Hadi Maazi, Meidi Gu, Fatemeh Masrorpour, Dawei Chen, Lisa Hettrick, Morgan Maureen Green, Natalie Wall Fowlkes, Claudia S. Kettlun Leyton, Liangpeng Yang, Carola Leuschner, Jie Zhang, Genevieve Bertolet, Mark D. Wasley, Duygu Sezen, Yun Hu, Nahum Puebla-Osorio, Hampartsoum B. Barsoumian, Kewen He
Supplementary Figures and Tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dd53f1cd8e2a3b7cf6692f53981db11
https://doi.org/10.1158/2326-6066.22551861
https://doi.org/10.1158/2326-6066.22551861
Autor:
James W. Welsh, Maria Angelica Cortez, Alexey S. Revenko, Hadi Maazi, Meidi Gu, Fatemeh Masrorpour, Dawei Chen, Lisa Hettrick, Morgan Maureen Green, Natalie Wall Fowlkes, Claudia S. Kettlun Leyton, Liangpeng Yang, Carola Leuschner, Jie Zhang, Genevieve Bertolet, Mark D. Wasley, Duygu Sezen, Yun Hu, Nahum Puebla-Osorio, Hampartsoum B. Barsoumian, Kewen He
Diverse factors contribute to the limited clinical response to radiotherapy (RT) and immunotherapy in metastatic non–small cell lung cancer (NSCLC), among which is the ability of these tumors to recruit a retinue of suppressive immune cells—such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb74bb2f288ee682e99ac14c63a429d7
https://doi.org/10.1158/2326-6066.c.6534807.v1
https://doi.org/10.1158/2326-6066.c.6534807.v1