Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Carol Tang"'
Autor:
Yan Zhang, Chi Yan Wong, Carine Z. J. Lim, Qingchang Chen, Zhonglang Yu, Auginia Natalia, Zhigang Wang, Qing You Pang, See Wee Lim, Tze Ping Loh, Beng Ti Ang, Carol Tang, Huilin Shao
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Current technologies to subtype glioblastoma (GBM), the most lethal brain tumor, require highly invasive brain biopsies. Here, we develop a dedicated analytical platform to achieve direct and multiplexed profiling of circulating RNAs in extr
Externí odkaz:
https://doaj.org/article/3a2f3d7de2f943d495f2efd2b80e76d0
Autor:
Melanie Si Yan Tan, Edwin Sandanaraj, Yuk Kien Chong, See Wee Lim, Lynnette Wei Hsien Koh, Wai Hoe Ng, Nguan Soon Tan, Patrick Tan, Beng Ti Ang, Carol Tang
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
STAT3 activates distinct transcriptional programmes within cancer cells. In this study, the authors find that, in glioma, a STAT3-mediated expression signature can stratify patients for targeted precision therapy.
Externí odkaz:
https://doaj.org/article/d61c46f20a3c44179f855b1383771751
Autor:
Siew Hong Leong, Kyaw Myo Lwin, Sze Sing Lee, Wai Har Ng, Kia Min Ng, Soo Yong Tan, Bee Ling Ng, Nigel P. Carter, Carol Tang, Oi Lian Kon
Publikováno v:
npj Precision Oncology, Vol 1, Iss 1, Pp 1-8 (2017)
Gastric cancer: Chromosome rearrangement linked to less aggressive tumors Gastric tumors often harbor a chromosome abnormality that disrupts a key signaling gene, resulting in less aggressive cancers. Oi Lian Kon from the National Cancer Centre Singa
Externí odkaz:
https://doaj.org/article/7bfd55e1ad994240a600d74fa922acd5
Autor:
Joanne Toh, Ling Ling Chua, Patrick Ho, Edwin Sandanaraj, Carol Tang, Hongyan Wang, Eng King Tan
Publikováno v:
Cells, Vol 10, Iss 1, p 76 (2021)
Parkinson’s disease (PD) is an age-dependent neurodegenerative condition. Leucine-rich repeat kinase 2 (LRRK2) mutations are the most frequent cause of sporadic and autosomal dominant PD. The exact role of LRRK2 protective variants (R1398H, N551K)
Externí odkaz:
https://doaj.org/article/6f6d4e20230f45c4b9a82332ef5571e1
Autor:
Beng Ti Ang, Carol Tang, Ivan Ng, Wai Hoe Ng, Greg Tucker-Kellogg, Oi Lian Kon, Siew Hong Leong, Swee Seong Wong, Mark Phong, Edwin Sandanaraj, Geraldene Rong-Hui Koh, Esther Hui-Ling Ting, Tan Boon Toh, Felicia Soo-Lee Ng
PDF file - 688K, Supplementary Fig. S1. NNI-8 GPCs display stemness expression and extensive self-renewal.Supplementary Fig. S2. NNI-8 orthotopic xenograft recapitulates patient tumor pathophysiology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::703b30891d9d2694cbe9d4c67ee4df2d
https://doi.org/10.1158/1078-0432.22443275.v1
https://doi.org/10.1158/1078-0432.22443275.v1
Autor:
Beng Ti Ang, Carol Tang, Ivan Ng, Wai Hoe Ng, Greg Tucker-Kellogg, Oi Lian Kon, Siew Hong Leong, Swee Seong Wong, Mark Phong, Edwin Sandanaraj, Geraldene Rong-Hui Koh, Esther Hui-Ling Ting, Tan Boon Toh, Felicia Soo-Lee Ng
Purpose: Patient-derived glioma-propagating cells (GPC) contain karyotypic and gene expression profiles that are found in the primary tumor. However, their clinical relevance is unclear. We ask whether GPCs contribute to disease progression and survi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a37b35ff8e93d27a56a4853cc92c65ad
https://doi.org/10.1158/1078-0432.c.6519749
https://doi.org/10.1158/1078-0432.c.6519749
Autor:
Kah-Leong Lim, Carol Tang, Ryosuke Takahashi, Beng-Ti Ang, Joanna D. Holbrook, Edwin Sandanaraj, Charlene S.F. Foong, Lynnette W.H. Koh, Yuk Kien Chong, Geraldene R.H. Koh, Jeanne M.M. Tan, Chou Chai, Felicia S.L. Ng, Calvin W.S. Yeo
Mutations in the parkin gene, which encodes a ubiquitin ligase, are a major genetic cause of parkinsonism. Interestingly, parkin also plays a role in cancer as a putative tumor suppressor, and the gene is frequently targeted by deletion and inactivat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abb9f03b215b799e214de69512817fed
https://doi.org/10.1158/0008-5472.c.6502959.v1
https://doi.org/10.1158/0008-5472.c.6502959.v1
Autor:
Kah-Leong Lim, Carol Tang, Ryosuke Takahashi, Beng-Ti Ang, Joanna D. Holbrook, Edwin Sandanaraj, Charlene S.F. Foong, Lynnette W.H. Koh, Yuk Kien Chong, Geraldene R.H. Koh, Jeanne M.M. Tan, Chou Chai, Felicia S.L. Ng, Calvin W.S. Yeo
PDF file - 64K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fe96a3645ea7acb872fd18ed47676d7
https://doi.org/10.1158/0008-5472.22390458
https://doi.org/10.1158/0008-5472.22390458
Autor:
Kah-Leong Lim, Carol Tang, Ryosuke Takahashi, Beng-Ti Ang, Joanna D. Holbrook, Edwin Sandanaraj, Charlene S.F. Foong, Lynnette W.H. Koh, Yuk Kien Chong, Geraldene R.H. Koh, Jeanne M.M. Tan, Chou Chai, Felicia S.L. Ng, Calvin W.S. Yeo
PDF file - 130K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0baf99cb3a4d8497ec067cc57d1b906e
https://doi.org/10.1158/0008-5472.22390461.v1
https://doi.org/10.1158/0008-5472.22390461.v1