Výsledky vyhledávání - "Carol St. Clair"

Effects of GH and/or sex steroids on circulating IGF-I and IGFBPs in healthy, aged women and men

Autor: Thomas Münzer, S. Mitchell Harman, John D. Sorkin, Clifford J. Rosen, Katherine M. Pabst, Marc R. Blackman, Carol St. Clair

Publikováno v: American Journal of Physiology-Endocrinology and Metabolism. 290:E1006-E1013

Circulating GH, IGF-I, IGFBP-3, and sex steroid concentrations decrease with age. GH or sex steroid treatment increases IGFBP-3, but little is known regarding the effects of these hormones on other IGFBPs. We assessed the effects of 26 wk of administ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::378d11e9783d974c4f454ab790331758
https://doi.org/10.1152/ajpendo.00166.2005

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Growth Hormone and Sex Steroid Effects on Bone Metabolism and Bone Mineral Density in Healthy Aged Women and Men

Autor: Michele Bellantoni, Jordan D. Tobin, Katharine M. Pabst, Colleen Christmas, Kieran G. O'Connor, Marc R. Blackman, John D. Sorkin, Carol St. Clair, S. Mitchell Harman, Thomas Münzer

Publikováno v: The Journals of Gerontology Series A: Biological Sciences and Medical Sciences. 57:M12-M18

Aging is associated with concomitant declines in activity of the growth hormone (GH) and gonadal steroid axes, and in bone mineral density (BMD), in both sexes. Long-term estrogen replacement slows bone loss and prevents fractures in postmenopausal w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ccc0c6795164e2211df03bceef220e8
https://doi.org/10.1093/gerona/57.1.m12

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Effects of GH and/or Sex Steroid Administration on Abdominal Subcutaneous and Visceral Fat in Healthy Aged Women and Men

Autor: Edward P. Shapiro, John D. Sorkin, S. Mitchell Harman, Thomas E. Stevens, Thomas Münzer, Kieran G. O'Connor, Carol St. Clair, Colleen Christmas, Michele Bellantoni, Paul S. Hees, Marc R. Blackman, Katherine M. Pabst

Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 86:3604-3610

Aging is associated with reduced GH, IGF-I, and sex steroid axis activity and with increased abdominal fat. We employed a randomized, double-masked, placebo-controlled, noncross-over design to study the effects of 6 months of administration of GH alo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3e121be47bc9de283584c6ec30bcabf
https://doi.org/10.1210/jcem.86.8.7773

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Cortisol and GH secretory dynamics, and their interrelationships, in healthy aged women and men

Autor: Carol St. Clair, Thomas E. Stevens, Jocelyn Jayme, Colleen Christmas, S. Mitchell Harman, Marc R. Blackman, Kieran G. O'Connor, Michele Bellantoni, Johannes D. Veldhuis, Katherine M. Pabst, Thomas Münzer, Jeffrey A. Gusenoff

Publikováno v: American Journal of Physiology-Endocrinology and Metabolism. 280:E616-E625

We studied 130 healthy aged women (n = 57) and men (n = 73), age 65–88 yr, with age-related reductions in insulin-like growth factor I and gonadal steroid levels to assess the interrelationships between cortisol and growth hormone (GH) secretion an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ccc33b07eecccf8450dc69c45bb813c
https://doi.org/10.1152/ajpendo.2001.280.4.e616

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Interrelationships of spontaneous growth hormone axis activity, body fat, and serum lipids in healthy elderly women and men

Autor: Colleen Christmas, M. Janette Busby-Whitehead, Carol St. Clair, Thomas Münzer, Ernest Cottrell, Michele Bellantoni, Tracey A. Roy, S. Mitchell Harman, Katherine M. Pabst, Jocelyn J. Jayme, Marc R. Blackman, Kieran G. O'Connor, Jordan D. Tobin, Thomas E. Stevens

Publikováno v: Metabolism: clinical and experimental. 48(11)

Aging is associated with decreased growth hormone (GH) secretion and plasma insulin-like growth factor-I (IGF-I) levels, increased total and abdominal fat, total and low-density lipoprotein (LDL) cholesterol, and triglycerides, and reduced high-densi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::360cbbd1f3a702093d0d5e3c48e44964
https://pubmed.ncbi.nlm.nih.gov/10582552

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Influence of Testosterone on the GH—IGF-I Axis in Healthy Elderly Men

Autor: E. Jeffrey Metter, Colleen Christmas, Thomas Muüzer, H. Ballentine Carter, Michele Bellantoni, Thomas E. Stevens, Marc R. Blackman, S. Mitchell Harman, Carol St. Clair, Kieran G. O'Connor, Katherine M. Pabst

Publikováno v: Sex-Steroid Interactions with Growth Hormone ISBN: 9780387988108

Numerous in vivo and in vitro animal studies attest to the complex interplay between gonadal steroids and the GHRH—somatostatin-GH—IGF-I axis in the male and female, a topic that has been excellently and extensively reviewed (1–3). In male rats

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::57857766187e90b2ef47525a7d70b302
https://doi.org/10.1007/978-1-4612-1546-2_5

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Growth Hormone and Sex Steroid Administration in Healthy Aged Women and Men

Autor: Jocelyn Jayme, Kieran G. O'Connor, John D. Sorkin, Jan Busby-Whitehead, Marc R. Blackman, Colleen Christmas, Kerry J. Stewart, Katharine M. Pabst, Ernest Cottrell, Thomas E. Stevens, Carol St. Clair, Michele Bellantoni, S. Mitchell Harman, Jordan D. Tobin, Thomas Münzer

Publikováno v: JAMA. 288:2282

ContextHormone administration to elderly individuals can increase lean body mass (LBM) and decrease fat, but interactive effects of growth hormone (GH) and sex steroids and their influence on strength and endurance are unknown.ObjectiveTo evaluate th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2f1b40867bc6ec1f87753ebf90dbada
https://doi.org/10.1001/jama.288.18.2282

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