Multi-Ancestry GWAS reveals excitotoxicity associated with outcome after ischaemic stroke

Autor: Laura Ibanez, Laura Heitsch, Caty Carrera, Fabiana H G Farias, Jorge L Del Aguila, Rajat Dhar, John Budde, Kristy Bergmann, Joseph Bradley, Oscar Harari, Chia Ling Phuah, Robin Lemmens, Alessandro A Viana Oliveira Souza, Francisco Moniche, Antonio Cabezas-Juan, Juan Francisco Arenillas, Jerzy Krupinksi, Natalia Cullell, Nuria Torres-Aguila, Elena Muiño, Jara Cárcel-Márquez, Joan Marti-Fabregas, Raquel Delgado-Mederos, Rebeca Marin-Bueno, Alejandro Hornick, Cristofol Vives-Bauza, Rosa Diaz Navarro, Silvia Tur, Carmen Jimenez, Victor Obach, Tomas Segura, Gemma Serrano-Heras, Jong Won Chung, Jaume Roquer, Carol Soriano-Tarraga, Eva Giralt-Steinhauer, Marina Mola-Caminal, Joanna Pera, Katarzyna Lapicka-Bodzioch, Justyna Derbisz, Antoni Davalos, Elena Lopez-Cancio, Lucia Muñoz, Turgut Tatlisumak, Carlos Molina, Marc Ribo, Alejandro Bustamante, Tomas Sobrino, Jose Castillo-Sanchez, Francisco Campos, Emilio Rodriguez-Castro, Susana Arias-Rivas, Manuel Rodríguez-Yáñez, Christina Herbosa, Andria L Ford, Alonso Gutierrez-Romero, Rodrigo Uribe-Pacheco, Antonio Arauz, Iscia Lopes-Cendes, Theodore Lowenkopf, Miguel A Barboza, Hajar Amini, Boryana Stamova, Bradley P Ander, Frank R Sharp, Gyeong Moon Kim, Oh Young Bang, Jordi Jimenez-Conde, Agnieszka Slowik, Daniel Stribian, Ellen A Tsai, Linda C Burkly, Joan Montaner, Israel Fernandez-Cadenas, Jin Moo Lee, Carlos Cruchaga

Publikováno v: BRAIN
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Brain : a journal of neurology, vol 145, iss 7
Brain
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol

Funding: This work was supported by grants from the Emergency Medicine Foundation Career Development Grant; AHA Mentored Clinical & Population Research Award (14CRP18860027); NIH/NINDS-R01-NS085419 (C.C., J.M.L.); NIH/NINDS-R37-NS107230, NIH/NINDS U2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06fffc2f858e2f88ba923cf23528639f
https://hdl.handle.net/10023/27061

MULTI-ANCESTRY GENETIC STUDY IN 5,876 PATIENTS IDENTIFIES AN ASSOCIATION BETWEEN EXCITOTOXIC GENES AND EARLY OUTCOMES AFTER ACUTE ISCHEMIC STROKE

Autor: Laura Ibanez, E. López-Cancio, Jose Castillo-Sanchez, Oh Young Bang, C. Herbosa, Joseph Bradley, Antonio Arauz, Jin-Moo Lee, Gyeong Moon Kim, Joan Montaner, Lucia Muñoz, Alejandro Bustamante, Joan Martí-Fàbregas, Francisco Moniche, Kristy Bergmann, Chia-Ling Phuah, Juan F. Arenillas, Iscia Lopes-Cendes, Laura Heitsch, Linda C. Burkly, Ellen A. Tsai, Jerzy Krupinksi, Silvia Tur, Tomás Sobrino, Susana Arias-Rivas, Raquel Delgado-Mederos, Elena Muiño, Oscar Harari, Katarzyna Lapicka-Bodzioch, Jara Cárcel-Márquez, Frank R. Sharp, Alejandro Hornick, Rajat Dhar, John P. Budde, Agnieszka Slowik, Bradley P. Ander, Robin Lemmens, Turgut Tatlisumak, Carlos Cruchaga, Antoni Dávalos, Hajar Amini, Daniel Stribian, Gemma Serrano-Heras, Justyna Derbisz, Boryana Stamova, Joanna Pera, Andria L. Ford, Carol Soriano-Tarraga, Jaume Roquer, Nuria P. Torres-Aguila, Manuel Rodríguez-Yáñez, Cristofol Vives-Bauza, Fabiana H.G. Farias, Theodore Lowenkopf, Miguel A Barboza, Alessandro A Viana Oliveira Souza, Carmen Jiménez, Marina Mola-Caminal, Antonio Cabezas-Juan, Marc Ribó, Jordi Jimenez-Conde, Tomás Segura, Caty Carrera, Eva Giralt-Steinhauer, Emilio Rodríguez-Castro, Victor Obach, Natalia Cullell, Rosa Díaz Navarro, Francisco Campos, Israel Fernandez-Cadenas, Jong-Won Chung, Carlos A. Molina, Rebeca Marin-Bueno

Publikováno v: medRxiv
article-version (status) pre
article-version (number) 1

During the first hours after stroke onset neurological deficits can be highly unstable: some patients rapidly improve, while others deteriorate. This early neurological instability has a major impact on long-term outcome. Here, we aimed to determine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef3010ab88e062b6b92c7029b7efb464
http://europepmc.org/articles/PMC7654887

Factors associated with early outcome in patients with large-vessel carotid strokes

Autor: Jose E Martínez-Rodríguez, Angel Ois, Jordi Jimenez-Conde, Elisa Cuadrado-Godia, Ana Rodríguez-Campello, Jaume Roquer, Sara Jimena, Jaume Capellades, Eva Giralt-Steinhauer, Carol Soriano-Tarraga

Publikováno v: Journal of Neurology, Neurosurgery & Psychiatry. 84:305-309

To describe the severity and early neurological deterioration (END) in patients with symptomatic carotid stenosis and to analyse the influence of related factors.Observational cohort study of patients with ischaemic stroke, ipsilateral carotid stenos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::656e480e5f4e4eba9d9c19ff87d5e241
https://doi.org/10.1136/jnnp-2012-303638