Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Carol Ruth Senn"'
Autor:
Carol Ruth Senn, Allan J. Robins, Michael J. Waters, Stan Bastiras, Julian R.E. Wells, Ross I. Brinkworth, S. W. Rowlinson, Ross Barnard
Publikováno v:
Biochemistry. 33:11724-11733
In this study we have demonstrated that the C-terminus of helix 1 of porcine GH (pGH) is a receptor-interactive region, thus extending the current binding site model of GH. This was achieved by introducing charge reversal mutations into this region o
Autor:
Andrew A. Somogyi, Dorothy M. K. Keefe, Angel F. Lopez, M A Vadas, Bronwyn Cambareri, Allan William Hey, Ian R. Doyle, Nancy A Olszewski, Trevor Rawling, Melinda Myers, Meera Verma, Ian N. Olver, Michael P. Brown, Stan Bastiras, David J. R. Foster, Peter Wigley, T.R. Hercus, L. Bik To, Carol Ruth Senn, Anne W. Taylor, Julie Cole
Publikováno v:
Cancer chemotherapy and pharmacology. 50(3)
Purpose. E21R is a competitive inhibitor of GM-CSF. This is the initial clinical study to investigate the safety, toxicity and pharmacokinetics of escalating doses of E21R. Patients and methods. Cohorts of three patients received doses of 10, 30, 100