Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Carol R. Sterling"'
Publikováno v:
Neuroscience. 286:1-12
Polycytosine-binding proteins (PCBPs) are RNA-binding proteins that participate in post-transcriptional control pathways. Among the diverse functions of these proteins is the interaction with a 27 nucleotide pyrimidine-rich domain within the 3′UTR
Publikováno v:
Journal of Neurochemistry. 109:1272-1284
Repeated nicotine administration induces tyrosine hydroxylase (TH) mRNA in rat midbrain. In this study we investigate the mechanisms responsible for this response using two models of midbrain dopamine neurons, rat ventral midbrain slice explant cultu
Autor:
Bistra B. Nankova, Necla Kudrick, Carol R. Sterling, Owen Chan, Juhye Lena Kim, A W Tank, Edmund F. La Gamma
Publikováno v:
Physiological Reports
Acute metabolic stress such as insulin-induced hypoglycemia triggers a counterregulatory response during which the release of catecholamines (epinephrine), the activation of tyrosine hydroxylase (TH) enzyme and subsequent compensatory catecholamine b
Publikováno v:
Journal of Neurochemistry. 94:731-741
Prolonged stress or chronic nicotine administration leads to induction of tyrosine hydroxylase (TH) in adrenal medulla and locus coeruleus (LC) of the rat. In this study we use mice that express a transgene encoding 4.5 kb of TH gene 5'-flanking regi
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 304:575-588
Nicotine is a powerful stimulant of the sympathoadrenal system, causing the release of peripheral catecholamines and activation of catecholamine biosynthesis. In previous reports, we have studied the mechanisms by which short-term nicotine treatment
Tyrosine hydroxylase (TH) plays a critical role in maintaining the appropriate concentrations of catecholamine neurotransmitters in brain and periphery, particularly during long-term stress, long-term drug treatment, or neurodegenerative diseases. It
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ad6c7113b87a793caa638d41aea5697
https://europepmc.org/articles/PMC2769040/
https://europepmc.org/articles/PMC2769040/
It is well established that long-term stress leads to induction of tyrosine hydroxylase (TH) mRNA and TH protein in adrenal medulla and brain. This induction is usually associated with stimulation of the TH gene transcription rate. However, a number
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::525cafb631ff30cfa845d20cdedb97be
https://europepmc.org/articles/PMC2674250/
https://europepmc.org/articles/PMC2674250/
Publikováno v:
Brain research. 1158
Long-term stress leads to the induction of tyrosine hydroxylase (TH) protein and enzymatic activity in the adrenal medulla. This adaptive response is necessary to maintain the catecholamine biosynthetic capacity of adrenal chromaffin cells during per
Publikováno v:
Journal of neurochemistry. 94(3)
Prolonged stress or chronic nicotine administration leads to induction of tyrosine hydroxylase (TH) in adrenal medulla and locus coeruleus (LC) of the rat. In this study we use mice that express a transgene encoding 4.5 kb of TH gene 5'-flanking regi
Publikováno v:
Molecular pharmacology. 66(4)
Chronic nicotine treatment (two daily subcutaneous injections administered approximately 12 h apart for 14 days) is associated with long-term inductions of tyrosine hydroxylase (TH) protein and TH mRNA in locus ceruleus (LC) neurons. These increases