Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Carol Otten-Evans"'
Autor:
Beverly J. Castner, Fiona H. Durie, Mary Gerhart, Yoshifumi Itoh, David H. Lynch, Roy A. Black, Jennifer L. Slack, Robert E. Miller, Yasunori Okada, Kendall M. Mohler, Hideaki Nagase, Carol Otten-Evans, Richard S. Johnson
Publikováno v:
Biochemical and Biophysical Research Communications. 225:400-405
Tumor necrosis factor-alpha is released from cells by a proteolytic cleavage. Previous work suggested that a specific, non-matrix metalloproteinase carries out this cleavage, but matrix metalloproteinases have also been implicated. In this paper, we
Autor:
Carol Otten-Evans, Kendall M. Mohler, Carl F. Ware, Paul D. Crowe, Barbara N. Walter, Roy A. Black
Publikováno v:
The Journal of Experimental Medicine
TNF is synthesized as a 26-kD membrane-anchored precursor and is proteolytically processed at the cell surface to yield the mature secreted 17-kD polypeptide. The 80-kD tumor necrosis factor (TNF) receptor (TNFR80) is also proteolytically cleaved at
Autor:
Kendall M. Mohler, Paul R. Sleath, Jeffrey N. Fitzner, Douglas Pat Cerretti, Mark Alderson, Suresh S. Kerwar, Dauphine S. Torranee, Carol Otten-Evans, Teresa Greenstreet, Kumudini Weerawarna, Shirley R. Kronheim, Melissa Petersen, Mary Gerhart, Carl J. Kozlosky, Carl J. March, Roy A. Black
Publikováno v:
Nature. 370(6486)
Tumour necrosis factor (tumour necrosis factor-alpha/cachectin) plays a critical role in certain physiological defensive responses but causes severe damage to the host organism when produced in excess. There are two forms of tumour necrosis factor, a
Autor:
Mary K. Kennedy, Carol Otten-Evans, Kathleen S. Picha, Peter Robert Baum, Kendall M. Mohler, Charles A. Janeway, Kurt D. Shanebeck, Kenneth H. Grabstein
Publikováno v:
European journal of immunology. 24(1)
T cell-dependent regulation of B cell growth and differentiation involves an interaction between CD40, a B cell surface molecule, and the CD40 ligand (CD40L) which is expressed on activated CD4+ T cells. In the current study, we show that recombinant