Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Carol M. Trim"'
Autor:
Jessica E. Holder, Christopher Ferguson, Elisabete Oliveira, Carlos Lodeiro, Carol M. Trim, Lee J. Byrne, Emilia Bertolo, Cornelia M. Wilson
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Lung cancer is a global health problem affecting millions of people each year. Non-small cell lung cancer (NSCLC) is the most common form of lung cancer with various conventional treatment available in the clinic. Application of these treatments alon
Externí odkaz:
https://doaj.org/article/ff4657231f1c4ca38df728b6c2c7d2dc
Publikováno v:
Toxins, Vol 12, Iss 12, p 774 (2020)
Snakebite envenomation (SBE) is a high-priority, neglected tropical disease. This devastating occupational health hazard disproportionately affects rural farming communities in tropical countries. This is exacerbated by the distribution and densities
Externí odkaz:
https://doaj.org/article/1f00760c6d1d409781dfbc0e0c3a978c
Publikováno v:
Progress in medicinal chemistry. 60
Difficult drug targets are becoming the normal course of business in drug discovery, sometimes due to large interacting surfaces or only small differences in selectivity regions. For these, a different approach is merited: compounds lying somewhere b
Publikováno v:
Journal of applied animal welfare science : JAAWS. 24(2)
The use of full spectrum illumination, including ultraviolet (UV), during captive husbandry of arachnids such as scorpions and theraphosids (tarantulas) is common practice in zoological institutions and amongst some hobbyists, as confirmed by a surve
Publikováno v:
Toxicon : official journal of the International Society on Toxinology. 185
The search for novel and relevant cancer therapeutics is continuous and ongoing. Cancer adaptations, resulting in therapeutic treatment failures, fuel this continuous necessity for new drugs to novel targets. Recently, researchers have started to inv
Publikováno v:
Toxins, Vol 12, Iss 774, p 774 (2020)
Toxins
Toxins
Snakebite envenomation (SBE) is a high-priority, neglected tropical disease. This devastating occupational health hazard disproportionately affects rural farming communities in tropical countries. This is exacerbated by the distribution and densities
Autor:
Steven A Trim, Carol M. Trim
Publikováno v:
British Journal of Pain. 7:179-188
Adequate pain control is still a significant challenge and largely unmet medical need in the 21st century. With many small molecules failing to reach required levels of potency and selectivity, drug discovery is once again turning to nature to replen
Publikováno v:
Experimental Cell Research. 317:423-432
Neuregulins are growth factors that signal via the ErbB3 and ErbB4 receptors. Here we show using immunohistochemistry that they are often expressed in the nucleus of a range of tumour types including soft tissue and breast. The Neuregulin 1 type I-β
Autor:
Andrew J. Racher, Elaine Martin, Christopher J. O’Malley, Gary Montague, Richard M. Alldread, Root Tracy S, Lang Dietmar, Jane F. Povey, Carol M. Trim, Marc Feary, Christopher Mark Smales
Publikováno v:
Journal of biotechnology. 184
Despite many advances in the generation of high producing recombinant mammalian cell lines over the last few decades, cell line selection and development is often slowed by the inability to predict a cell line's phenotypic characteristics (e.g. growt