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pro vyhledávání: '"Carol M. McDonald"'
Publikováno v:
Stem Cell Research, Vol 16, Iss 2, Pp 259-263 (2016)
ZFP57 maintains genomic imprinting in mouse embryos and ES cells. To test its roles during iPS reprogramming, we derived iPS clones by utilizing retroviral infection to express reprogramming factors in mouse MEF cells. After analyzing four imprinted
Externí odkaz:
https://doaj.org/article/8365829b5a4240e0bff7b1f75d16e176
Publikováno v:
Stem Cell Research, Vol 16, Iss 2, Pp 259-263 (2016)
ZFP57 maintains genomic imprinting in mouse embryos and ES cells. To test its roles during iPS reprogramming, we derived iPS clones by utilizing retroviral infection to express reprogramming factors in mouse MEF cells. After analyzing four imprinted
Autor:
Andrew S. Cross, Judy K. Shigenaga, Kenneth R. Feingold, Mahmood R. Kazemi, Carol M. McDonald, Carl Grunfeld, Arthur H. Moser, Sophie Patzek
Publikováno v:
Journal of Leukocyte Biology. 92:829-839
TLR activation by multiple pathways leads to triglyceride accumulation in macrophages that could contribute to the accelerated atherosclerosis seen in chronic infections and inflammatory diseases. LPS treatment of macrophages induces TG accumulation,
Autor:
Carol M. McDonald, Michael Kyba, Ho-Tak Lau, Dana E. Cullen, Monica Andrade, Jipo Sheng, Xiajun Li, Guoliang Xu, Fong T. Bell, Michelina Iacovino, Xiaopan Zuo
Publikováno v:
Journal of Biological Chemistry. 287:2107-2118
Previously, we discovered that ZFP57 is a maternal-zygotic effect gene, and it maintains DNA methylation genomic imprint at multiple imprinted regions in mouse embryos. Despite these findings, it remains elusive how DNA methyltransferases are targete
Autor:
Judy K. Shigenaga, Kenneth R. Feingold, Sophie Patzek, Carol M. McDonald, Constantine Londos, Lisa G. Chui, Carl Grunfeld, Amy L. Magra, Mahmood R. Kazemi, Zoe W. Chan
Publikováno v:
Atherosclerosis. 209:81-88
Activation of macrophages by TLR agonists enhances foam cell formation, but the underlying mechanisms are not understood. We examined the effects of TLR agonists on ADRP/ADFP, a protein associated with forming lipid droplets, and Mal1 a fatty acid-bi
Publikováno v:
Journal of General Virology. 91:622-629
Ten novel mutations were introduced into the Zp promoter to test the role of sequences outside the established transcription factor-binding sites in Epstein-Barr virus (EBV) reactivation. Most of these had only small effects, but mutations in the ZID
Publikováno v:
Journal of Virology. 83:3397-3401
The Epstein-Barr virus (EBV) protein BZLF1 contains a bZIP DNA binding domain in which C-terminal tail residues fold back against a zipper region that forms a coiled coil and mediates dimerization. Point mutagenesis in the zipper region reveals the i
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 25(6)
Objective— Toll-like receptors (TLRs) recognize pathogens and mediate signaling pathways important for host defense. Recent studies implicate TLR polymorphisms in atherosclerosis risk in humans. Adipocyte fatty acid–binding protein (aP2) is prese