Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Carol M. Belton"'
Autor:
Sahba Fatherazi, Shiwei Cai, Kenneth T. Izutsu, Mark M. Schubert, Paul C. Goodwin, Carol M. Belton, Frank A. Roberts, Richard B. Presland
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 452:43-52
External calcium ion concentration is a major regulator of epidermal keratinocyte differentiation in vitro and probably also in vivo. Regulation of calcium-induced differentiation changes is proposed to occur via an external calcium-sensing, signalin
Autor:
Sahba Fatherazi, Mark M. Schubert, Richard J. Lamont, Kenneth T. Izutsu, Carol M. Belton, Paul C. Goodwin
Publikováno v:
Microbes and Infection. 6:440-447
The periodontal pathogen Porphyromonas gingivalis modulates epithelial cell signal transduction pathways including Ca2+ signaling, and internalizes within the host cell cytoplasm. Since nuclear and cytoplasmic [Ca2+] increases can induce different ho
Publikováno v:
Journal of Investigative Dermatology. 121(1):120-131
Calcium ion store-activated currents in undifferentiated human gingival keratinocytes were measured with the whole cell patch clamp and fura techniques. Thapsigargin or intracellular inositol 1,4,5-trisphosphate and BAPTA rapidly induced an early tra
Publikováno v:
Cellular Microbiology. 1:215-223
We have developed a fluorescence imaging technique using a DNA-binding dye to visualize, over time, the physical interactions between Porphyromonas gingivalis and human gingival epithelial cells in vitro. The results extend previous observations of P
Publikováno v:
Infection and Immunity. 66:1660-1665
Periodontitis, which is widespread in the adult population, is a persistent bacterial infection associated with Porphyromonas gingivalis . Gingival epithelial cells are among the first cells encountered by both P. gingivalis and commensal oral bacter
Publikováno v:
Infection and Immunity. 65:313-316
Porphyromonas gingivalis is a periodontal pathogen capable of invading primary cultures of normal human gingival epithelial cells (NHGEC). Involvement of P. gingivalis fimbriae in the invasion process was examined. Purified P. gingivalis 33277 fimbri
Publikováno v:
Journal of Histochemistry & Cytochemistry. 42:41-47
The GTP-binding protein G(o) was localized immunohistochemically in the rat parotid gland and in other exocrine glands with specific G(o) antibodies. Immunohistochemical studies revealed that affinity-purified G(o alpha) polyclonal antibody (GO/85) i
Publikováno v:
Journal of dermatological science. 40(1)
Summary Background: Extracellular calcium is an important regulator of keratinocyte differentiation. An increase in intracellular calcium ion concentration is required for activation of calcium-induced keratinocyte differentiation. The signaling elem
Autor:
Shiwei Cai, Shukriya Zarif, Paul C. Goodwin, Sahba Fatherazi, Kenneth T. Izutsu, Richard J. Lamont, Carol M. Belton
Publikováno v:
Pflugers Archiv : European journal of physiology. 448(1)
Calcium-sensing receptor (CaSR) expression and function were studied in proliferating and differentiating cultured human gingival keratinocytes (HGKs). CaSR mRNA and protein were present in proliferating HGKs cultured in 0.03 mM [Ca(2+)] and decrease
Publikováno v:
Infection and immunity. 69(11)
Mitogen-activated protein (MAP) kinase pathways are key factors in host signaling events and can also play important roles in the internalization of pathogenic bacteria by host cells.Porphyromonas gingivalis, a periodontal pathogen,can efficiently in