Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Carol M, Miyamoto"'
Autor:
David Y. Thomas, Carol M. Miyamoto, Qi Yang, Elizabeth Matthes, Graeme W. Carlile, Renaud Robert, Stevo Radinovic, Jie Liao, John W. Hanrahan
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-16 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-16 (2018)
Pharmacological chaperones (e.g. VX-809, lumacaftor) that bind directly to F508del-CFTR and correct its mislocalization are promising therapeutics for Cystic Fibrosis (CF). However to date, individual correctors provide only ~4% improvement in lung f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f56aac159919c6dd2aeab003f7aa6061
http://europepmc.org/articles/PMC6065411
http://europepmc.org/articles/PMC6065411
Autor:
Mathieu Rousseau, Mathieu Blanchette, Carol M. Miyamoto, Xue Qing David Wang, Solomon Shenker, Maria Ferraiuolo, Josée Dostie, Michelle Nadler
Publikováno v:
Nucleic Acids Research
Spatial chromatin organization is emerging as an important mechanism to regulate the expression of genes. However, very little is known about genome architecture at high-resolution in vivo. Here, we mapped the three-dimensional organization of the hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45af712c503299a6274b9b4c4a109c36
https://doi.org/10.1093/nar/gkq644
https://doi.org/10.1093/nar/gkq644
Autor:
Peter Bossier, Tom Defoirdt, Edward A. Meighen, Thomas K. Wood, Willy Verstraete, Patrick Sorgeloos, Carol M. Miyamoto
Publikováno v:
Environmental Microbiology. 9:2486-2495
This study aimed at getting a deeper insight in the molecular mechanism by which the natural furanone (5Z)-4-bromo-5-(bromomethylene)-3-butyl-2(5H)-furanone disrupts quorum sensing in Vibrio harveyi. Bioluminescence experiments with signal molecule r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1af06a9694a3dfdbcd3335be9acc0351
https://doi.org/10.1111/j.1462-2920.2007.01367.x
https://doi.org/10.1111/j.1462-2920.2007.01367.x
Publikováno v:
Applied and Environmental Microbiology. 70:5603-5612
Biochemical characterization of the purified bile salt hydrolase (BSH) from Bifidobacterium bifidum ATCC 11863 revealed some distinct characteristics not observed in other species of Bifidobacterium . The bsh gene was cloned from B. bifidum , and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14365f5496fafdbad4984fe8cfe9da46
https://doi.org/10.1128/aem.70.9.5603-5612.2004
https://doi.org/10.1128/aem.70.9.5603-5612.2004
Publikováno v:
Molecular Microbiology. 48:537-548
Summary + counterparts. These results suggest that activity of the autoinducer- mediated phosphorelay system is coupled to LuxR vh / LitR control of luminescence through LuxO in V. har- veyi and V. fischeri . The presence of homologues of V. harveyi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65209650b1054c2b35ac86fe63e19264
https://doi.org/10.1046/j.1365-2958.2003.03453.x
https://doi.org/10.1046/j.1365-2958.2003.03453.x
Autor:
Nicolas Skouris, Edward A. Meighen, Carol M. Miyamoto, Jaidip Chatterjee, Athina Zouzoulas, B. Franz Lang
Publikováno v:
Molecular Microbiology. 46:101-111
The induction of luminescence in Vibrio harveyi at the later stages of growth is controlled by a quorum-sensing mechanism in addition to nutritional signals. However, the mechanism of transmission of these signals directly to the lux promoters is unk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab26aa06dc9674ae64c4aa7447e157e0
https://doi.org/10.1046/j.1365-2958.2002.03128.x
https://doi.org/10.1046/j.1365-2958.2002.03128.x
Publikováno v:
Molecular Microbiology. 45:131-143
Vibrio fischeri is the bacterial symbiont within the light-emitting organ of the sepiolid squid Euprymna scolopes. Upon colonizing juvenile squids, bacterial symbionts grow on host-supplied nutrients, while providing a bioluminescence that the host u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1b77a1a5b0c96de57ccc3914cc38841
https://doi.org/10.1046/j.1365-2958.2002.02996.x
https://doi.org/10.1046/j.1365-2958.2002.02996.x
Publikováno v:
Molecular Microbiology. 36:594-607
Bioluminescence in the marine bacterium Vibrio fischeri is controlled by the excretion of a N-acyl homoserine lactone (HSL) autoinducer which interacts with a regulator, LuxR, and activates transcription of the lux operon at high-cell density. This s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60991a01399d5c8e3aab942eec670a98
https://doi.org/10.1046/j.1365-2958.2000.01875.x
https://doi.org/10.1046/j.1365-2958.2000.01875.x
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1494:226-235
LuxO is the central regulator integrating the quorum sensing signals controlling autoinduction of luminescence in Vibrio harveyi. We have previously purified to homogeneity a new lux regulator, LuxT, that binds to the luxO promoter. Based on the sequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6168ce4798358cc16f4625490690ecb
https://doi.org/10.1016/s0167-4781(00)00236-0
https://doi.org/10.1016/s0167-4781(00)00236-0
Publikováno v:
Protein Expression and Purification. 20:87-94
Bioluminescence in the marine bacterium Vibrio harveyi is cell density dependent and is regulated by small molecules (autoinducers) excreted by the bacteria. The autoinducer signals are relayed to a central regulator, LuxO, which acts in its phosphor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd99267f1c3e691ff88db658c777df8b
https://doi.org/10.1006/prep.2000.1285
https://doi.org/10.1006/prep.2000.1285