Expression of Endogenous Putative TSH Binding Protein in Orbit

Autor: Mohd Shazli Draman, Fiona Grennan-Jones, Peter Taylor, Ilaria Muller, Sam Evans, Anjana Haridas, Daniel S. Morris, D. Aled Rees, Carol Lane, Colin Dayan, Lei Zhang, Marian Ludgate

Publikováno v: Current Issues in Molecular Biology, Vol 43, Iss 3, Pp 1794-1804 (2021)

Thyroid stimulating antibodies (TSAB) cause Graves’ disease and contribute to Graves’ Orbitopathy (GO) pathogenesis. We hypothesise that the presence of TSH binding proteins (truncated TSHR variants (TSHRv)) and/or nonclassical ligands such as th

Externí odkaz: https://doaj.org/article/51b8990d34914620a6eea41a39459725

Review: Therapeutic options for continuous dopaminergic stimulation in Parkinson's disease

Autor: O.K. Sujith, Carol Lane

Publikováno v: Therapeutic Advances in Neurological Disorders, Vol 2 (2009)

Treatment of Parkinson's disease aims to replace dopaminergic transmission at striatal synapses. In the normal state, nigral neurons fire continuously, exposing striatal dopamine receptors to relatively constant levels of dopamine. In the disease sta

Externí odkaz: https://doaj.org/article/c338a06dd15d491e9999471cc8779a5b

Total Pelvic Exenteration surgery - Considerations for healthcare professionals

Autor: Filipe Carvalho, Shengyang Qiu, Vasia Panagi, Katy Hardy, Hannah Tutcher, Marta Machado, Francisca Silva, Caroline Dinen, Carol Lane, Alleh Jonroy, Jon Knox, Lynn Worley, Jessica Whibley, Tobias Perren, Jane Thain, Jacqueline McPhail

Publikováno v: European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology.

Associated with considerable risk of morbidity, Total Pelvic Exenteration (TPE) is a life-altering procedure involving a significant prolonged recovery. As a result, and with the view of achieving the best outcomes and lessen short and long-term morb

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eef51fbc9056298c589df5369adcd68c
https://pubmed.ncbi.nlm.nih.gov/36030135

Mycophenolate plus methylprednisolone versus methylprednisolone alone in active, moderate-to-severe Graves' orbitopathy (MINGO): a randomised, observer-masked, multicentre trial

Autor: George J Kahaly, Michaela Riedl, Jochem König, Susanne Pitz, Katharina Ponto, Tanja Diana, Elena Kampmann, Elisa Kolbe, Anja Eckstein, Lars C Moeller, Dagmar Führer, Mario Salvi, Nicola Curro, Irene Campi, Danila Covelli, Marenza Leo, Michele Marinò, Francesca Menconi, Claudio Marcocci, Luigi Bartalena, Petros Perros, Wilmar M Wiersinga, Göksun Ayvaz, Lelio Baldeschi, Kostas Boborides, Antonella Boschi, Thomas H Brix, Lucy Clarke, Colin Dayan, Chantal Daumerie, A Jane Dickinson, Nicole Fichter, Laszlo Hegedüs, Onur Konuk, Gerassimos E Krassas, Carol Lane, John Lazarus, Dan S Morris, Maarten. Mourits, Marco Nardi, Chris Neoh, Jacques Orgiazzi, Simon H S Pearce, Georg von Arx, Milos Zarkovic

Publikováno v: Kahaly, G J, Riedl, M, König, J, Pitz, S, Ponto, K, Diana, T, Kampmann, E, Kolbe, E, Eckstein, A, Moeller, L C, Führer, D, Salvi, M, Curro, N, Campi, I, Covelli, D, Leo, M, Marinò, M, Menconi, F, Marcocci, C, Bartalena, L, Perros, P, Wiersinga, W M, European Group on Graves' Orbitopathy (EUGOGO), Hegedüs, L & Brix, T 2018, ' Mycophenolate plus methylprednisolone versus methylprednisolone alone in active, moderate-to-severe Graves' orbitopathy (MINGO) : a randomised, observer-masked, multicentre trial ', The Lancet Diabetes & Endocrinology, vol. 6, no. 4, pp. 287-298 . https://doi.org/10.1016/S2213-8587(18)30020-2
Lancet. Diabetes and endocrinology, 6(4), 287-298. Elsevier BV

BACKGROUND: European guidelines recommend intravenous methylprednisolone as first-line treatment for active and severe Graves' orbitopathy; however, it is common for patients to have no response or have relapse after discontinuation of treatment. We

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edc4643f6e3fc6e4807c854403320050
https://pubmed.ncbi.nlm.nih.gov/29396246

Variation in the Vitreous Phenotype of Stickler Syndrome Can Be Caused by Different Amino Acid Substitutions in the X Position of the Type II Collagen Gly‐X‐Y Triple Helix

Autor: Allan J. Richards, David M. Baguley, John R. W. Yates, Carol Lane, Mary Nicol, Peter S. Harper, John D. Scott, Martin P. Snead

Publikováno v: The American Journal of Human Genetics. 67:1083-1094

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ef048ef52f98f3122774c410ffcb1af9
https://doi.org/10.1086/321189